4YA1
Yeast 20S proteasome beta2-H116N mutant
Summary for 4YA1
| Entry DOI | 10.2210/pdb4ya1/pdb |
| Related | 1RYP |
| Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (17 entities in total) |
| Functional Keywords | hydrolase, proteasome, mutant, binding analysis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Saccharomyces cerevisiae S288c More |
| Total number of polymer chains | 28 |
| Total formula weight | 731363.24 |
| Authors | Huber, E.M.,Groll, M. (deposition date: 2015-02-17, release date: 2015-06-17, Last modification date: 2024-01-10) |
| Primary citation | Huber, E.M.,de Bruin, G.,Heinemeyer, W.,Paniagua Soriano, G.,Overkleeft, H.S.,Groll, M. Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137:7835-7842, 2015 Cited by PubMed: 26020686DOI: 10.1021/jacs.5b03688 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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