PDB: 31311 件ウェブページステータス検索Chemie searchBIRD

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6NBT	CRISPR Complex Subunit Csm3 from Staphylococcus epidermidis RP62a 分子名称: CALCIUM ION, CRISPR-associated protein, SAMARIUM (III) ION 著者 Dorsey, B.W, Mondragon, A. 登録日 2018-12-10 公開日 2019-02-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural organization of a Type III-A CRISPR effector subcomplex determined by X-ray crystallography and cryo-EM. Nucleic Acids Res., 47, 2019
7ZOG	Crystal structure of Cryptosporidium parvum -Plasmodium falciparum mutant lysyl tRNA synthetase in complex with inhibitor 分子名称: 8-[[4-[2-[2-[2-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]sulfonylamino]-~{N}-(cyclohexylmethyl)-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, GLYCEROL, LYSINE, ... 著者 Dawson, A, Wyllie, S. 登録日 2022-04-25 公開日 2022-09-07 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase. Acs Infect Dis., 8, 2022
7ZGN	Plant/insect N-glycan active PNGase 分子名称: Glpgli family protein 著者 Basle, A, Crouch, L, Bolam, D. 登録日 2022-04-04 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Plant N -glycan breakdown by human gut Bacteroides. Proc.Natl.Acad.Sci.USA, 119, 2022
7WGP	X-ray structure of human PPAR gamma ligand binding domain-fenofibric acid co-crystals obtained by co-crystallization 分子名称: 15-meric peptide from Nuclear receptor coactivator 1, 2-[4-(4-chlorobenzene-1-carbonyl)phenoxy]-2-methylpropanoic acid, Isoform 1 of Peroxisome proliferator-activated receptor gamma 著者 Kamata, S, Honda, A, Akahane, M, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I. 登録日 2021-12-28 公開日 2022-05-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate. Int J Mol Sci, 23, 2022
7ZML	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001 分子名称: ATP-dependent DNA helicase Q5, Gluebody G1-001, SULFATE ION, ... 著者 Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. 登録日 2022-04-19 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
5FNM	Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination 分子名称: (~{E})-3-(4-methoxyphenyl)but-2-enoic acid, CARBONIC ANHYDRASE 2, ZINC ION 著者 Woods, L.A, Dolezal, O, Ren, B, Ryan, J.H, Peat, T.S, Poulsen, S.A. 登録日 2015-11-15 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59, 2016
8PEA	OXA-48_F72L. Epistasis Arises from Shifting the Rate-Limiting Step during Enzyme Evolution 分子名称: Beta-lactamase, CHLORIDE ION 著者 Leiros, H.-K.S, Frohlich, C. 登録日 2023-06-13 公開日 2024-02-14 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Epistasis arises from shifting the rate-limiting step during enzyme evolution of a beta-lactamase. Nat Catal, 7, 2024
6NC4	FtsY-NG high-resolution 分子名称: ACETATE ION, AMMONIUM ION, GLYCEROL, ... 著者 Ataide, S.F, Faoro, C. 登録日 2018-12-10 公開日 2019-10-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into the G-loop dynamics of E. coli FtsY NG domain. J.Struct.Biol., 208, 2019
7ZLU	Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-2-deoxy-2-fluoro-D-glucose 分子名称: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Roversi, P, Zitzmann, N, Bayo, Y, Ibba, R. 登録日 2022-04-15 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint. Iscience, 26, 2023
8PEB	OXA-48_Q5. Epistasis Arises from Shifting the Rate-Limiting Step during Enzyme Evolution 分子名称: Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Leiros, H.-K.S, Frohlich, C. 登録日 2023-06-13 公開日 2024-02-14 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Epistasis arises from shifting the rate-limiting step during enzyme evolution of a beta-lactamase. Nat Catal, 7, 2024
6NCH	Crystal structure of CDP-Chase: Raster data collection 分子名称: D-ribose, PHOSPHATE ION, Phosphohydrolase (MutT/nudix family protein), ... 著者 Miller, M.S, Shi, W, Gabelli, S.B. 登録日 2018-12-11 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
8W4D	Crystal structure of the sigma-1 receptor from Xenopus laevis in the absence of known ligands 分子名称: Sigma non-opioid intracellular receptor 1 著者 Xiao, Y, Fu, C, Sun, Z, Zhou, X. 登録日 2023-08-23 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.173 Å) 主引用文献 Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor. Nat Commun, 15, 2024
7O4U	Structure of the alpha subunit of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide 分子名称: 3-hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Dalwani, S, Wierenga, R.K, Venkatesan, R. 登録日 2021-04-07 公開日 2021-08-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
7OCZ	Crystal Structure of the PID-3 RRM domain 分子名称: CHLORIDE ION, Protein pid-3 著者 Basquin, J, Ketting, R.F, Falk, S. 登録日 2021-04-28 公開日 2021-08-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans . Genes Dev., 35, 2021
7WGO	X-ray structure of human PPAR gamma ligand binding domain-bezafibrate co-rystals obtained by co-crystallization 分子名称: 15-meric peptide from Nuclear receptor coactivator 1, 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, Isoform 1 of Peroxisome proliferator-activated receptor gamma 著者 Kamata, S, Honda, A, Akahane, M, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I. 登録日 2021-12-28 公開日 2022-05-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate. Int J Mol Sci, 23, 2022
5FIW	CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE AT 1.7 ANGSTROMS RESOLUTION 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Bonnefond, L, Cavarelli, J. 登録日 2015-10-02 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Human Myeloperoxidase at 1.7 Angstroms Resolution To be Published
7O6N	Crystal structure of C. elegans ERH-2 PID-3 complex 分子名称: Enhancer of rudimentary homolog 2, FORMIC ACID, Protein pid-3 著者 Falk, S, Ketting, R.F. 登録日 2021-04-11 公開日 2021-08-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans . Genes Dev., 35, 2021
5FJY	Crystal structure of mouse kinesin light chain 2 (residues 161-480) 分子名称: KINESIN LIGHT CHAIN 2, UNKNOWN PEPTIDE 著者 Pernigo, S, Yip, Y.Y, Sanger, A, Xu, M, Dodding, M.P, Steiner, R.A. 登録日 2015-10-14 公開日 2016-02-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 The Light Chains of Kinesin-1 are Autoinhibited. Proc.Natl.Acad.Sci.USA, 113, 2016
8SKB	Crystal Structure of GDP-mannose 3,5 epimerase de Myrciaria dubia in complex with NAD 分子名称: GDP-mannose 3,5 epimerase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C. 登録日 2023-04-19 公開日 2024-03-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural insights into the Smirnoff-Wheeler pathway for vitamin C production in the Amazon fruit camu-camu. J.Exp.Bot., 75, 2024
7WGN	X-ray structure of human PPAR delta ligand binding domain-pemafibrate co-crystals obtained by co-crystallization 分子名称: (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, Peroxisome proliferator-activated receptor delta, octyl beta-D-glucopyranoside 著者 Kamata, S, Honda, A, Akahane, M, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I. 登録日 2021-12-28 公開日 2022-05-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.813 Å) 主引用文献 Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate. Int J Mol Sci, 23, 2022
7OCX	Crystal Structure of the PID-3 TOFU-6 RRM domain complex 分子名称: Embryonic developmental protein tofu-6, Protein pid-3 著者 Basquin, J, Ketting, R.F, Falk, S. 登録日 2021-04-28 公開日 2021-08-25 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans . Genes Dev., 35, 2021
5D5U	Crystal structure of human Hsf1 with HSE DNA 分子名称: Heat shock Element DNA, Heat shock factor protein 1 著者 Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. 登録日 2015-08-11 公開日 2015-12-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
7ZHI	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor indole 分子名称: Aspartate carbamoyltransferase, INDOLE, SULFATE ION 著者 Wang, C, Zhang, B. 登録日 2022-04-06 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.946 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
8SNZ	X-ray Crystal Structure of FMN-bound long-chain flavodoxin from Rhodopseudomonas palustris 分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin 著者 Ansari, A, Khan, S.A, Miller, A.F. 登録日 2023-04-28 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structure, dynamics, and redox reactivity of an all-purpose flavodoxin. J.Biol.Chem., 300, 2024
5VDO	Human cyclic GMP-AMP synthase (cGAS) in complex with 2',2'-cGAMP 分子名称: 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, Cyclic GMP-AMP synthase, ZINC ION 著者 Byrnes, L.J, Hall, J.D. 登録日 2017-04-03 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.218 Å) 主引用文献 The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017

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