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2Y3K
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Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 1
分子名称: AMYLOID BETA A4 PROTEIN
著者Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D.
登録日2010-12-21
公開日2011-11-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
3HC5
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FXR with SRC1 and GSK826
分子名称: 3-(6-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1-benzothiophen-2-yl)benzoic acid, Bile acid receptor, Nuclear receptor coactivator 1, ...
著者Williams, S.P, Madauss, K.P.
登録日2009-05-05
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献FXR agonist activity of conformationally constrained analogs of GW 4064.
Bioorg.Med.Chem.Lett., 19, 2009
3CSH
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Crystal Structure of Glutathione Transferase Pi in complex with the Chlorambucil-Glutathione Conjugate
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Parker, L.J.
登録日2008-04-09
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants.
J.Mol.Biol., 380, 2008
3CT1
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Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Morphogenesis protein 1
著者Xiang, Y, Rossmann, M.G.
登録日2008-04-11
公開日2008-07-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CV8
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Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84F mutant)
分子名称: Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE
著者Hayashi, K, Sugimoto, H, Shinkyo, R, Yamada, M, Ikeda, S, Ikushiro, S, Kamakura, M, Shiro, Y, Sakaki, T.
登録日2008-04-18
公開日2008-11-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1
Biochemistry, 47, 2008
3CWL
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Crystal structure of alpha-1-antitrypsin, crystal form B
分子名称: Alpha-1-antitrypsin, CHLORIDE ION
著者Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W.
登録日2008-04-22
公開日2008-09-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
3CYF
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Crystal Structure of E18N DJ-1
分子名称: Protein DJ-1
著者Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A.
登録日2008-04-25
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Biochemistry, 47, 2008
3CZ9
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Crystal Structure of E18L DJ-1
分子名称: O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Protein DJ-1
著者Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A.
登録日2008-04-28
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Biochemistry, 47, 2008
3D81
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Sir2-S-alkylamidate complex crystal structure
分子名称: NAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION
著者Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C.
登録日2008-05-22
公開日2008-09-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16, 2008
1OH5
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THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A C:A MISMATCH
分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*CP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP *CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*AP*TP*GP*GP *CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K.
登録日2003-05-23
公開日2003-08-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1OH6
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THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN A:A MISMATCH
分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*AP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP* CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*AP*TP*GP*GP* CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K.
登録日2003-05-23
公開日2003-08-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
3H47
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X-ray Structure of Hexameric HIV-1 CA
分子名称: Capsid protein p24
著者Pornillos, O.
登録日2009-04-18
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
1OOJ
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Structural genomics of Caenorhabditis elegans : Calmodulin
分子名称: CALCIUM ION, Calmodulin CMD-1
著者Symersky, J, Lin, G, Li, S, Qiu, S, Luan, C.-H, Luo, D, Tsao, J, Carson, M, DeLucas, L, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-03-03
公開日2003-03-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural genomics of caenorhabditis elegans: crystal structure of calmodulin.
Proteins, 53, 2003
1OH8
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THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN UNPAIRED THYMIDINE
分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP* TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*CP*TP*TP*GP*GP*CP* AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K.
登録日2003-05-23
公開日2003-08-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1OT7
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Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR
分子名称: 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile Acid Receptor, ISO-URSODEOXYCHOLIC ACID, ...
著者Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F.
登録日2003-03-21
公開日2004-03-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1OH7
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THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A G:G MISMATCH
分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP *CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*GP*TP*GP*GP *CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K.
登録日2003-05-23
公開日2003-08-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates
Nucleic Acids Res., 31, 2003
1OZF
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The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
分子名称: Acetolactate synthase, catabolic, DI(HYDROXYETHYL)ETHER, ...
著者Pang, S.S, Duggleby, R.G, Schowen, R.L, Guddat, L.W.
登録日2003-04-09
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structures of Klebsiella pneumoniae Acetolactate Synthase with Enzyme-bound Cofactor and with an Unusual Intermediate.
J.Biol.Chem., 279, 2004
3GUH
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Crystal Structure of Wild-type E.coli GS in complex with ADP and DGM
分子名称: (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, 1,5-anhydro-D-glucitol, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
著者Sheng, F, Geiger, J.
登録日2009-03-30
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase.
J.Biol.Chem., 284, 2009
3CZA
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Crystal Structure of E18D DJ-1
分子名称: MALONIC ACID, Protein DJ-1
著者Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hashim, S, Pozharski, E, Wilson, M.A.
登録日2008-04-28
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Biochemistry, 47, 2008
1P7H
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Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element
分子名称: 5'-D(*AP*AP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*A)-3', 5'-D(*TP*TP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*A)-3', Nuclear factor of activated T-cells, ...
著者Giffin, M.J, Stroud, J.C, Bates, D.L, von Koenig, K.D, Hardin, J, Chen, L.
登録日2003-05-01
公開日2003-09-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element
Nat.Struct.Biol., 10, 2003
3GJX
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Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP
分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ...
著者Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R.
登録日2009-03-09
公開日2009-05-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP.
Science, 2009
1OZH
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The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate.
分子名称: 2-HYDROXYETHYL DIHYDROTHIACHROME DIPHOSPHATE, Acetolactate synthase, catabolic, ...
著者Pang, S.S, Duggleby, R.G, Schowen, R.L, Guddat, L.W.
登録日2003-04-09
公開日2003-11-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structures of Klebsiella pneumoniae Acetolactate Synthase with Enzyme-bound Cofactor and with an Unusual Intermediate.
J.Biol.Chem., 279, 2004
1Q81
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Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit.
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Insights into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
3GQ7
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Crystal Structure of the Bacteriophage Phi29 Gene Product 12 N-terminal Fragment
分子名称: CALCIUM ION, CARBONATE ION, MAGNESIUM ION, ...
著者Xiang, Y, Rossmann, M.G.
登録日2009-03-24
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystallographic insights into the autocatalytic assembly mechanism of a bacteriophage tail spike.
Mol.Cell, 34, 2009
3GKE
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Crystal Structure of Dicamba Monooxygenase
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DdmC, ...
著者Wilson, M.A, Dumitru, R, Jiang, W.Z, Weeks, D.P.
登録日2009-03-10
公開日2009-07-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation.
J.Mol.Biol., 392, 2009

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