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3D81

Sir2-S-alkylamidate complex crystal structure

Summary for 3D81
Entry DOI10.2210/pdb3d81/pdb
Related3D4B
DescriptorNAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION, ... (4 entities in total)
Functional Keywordsrossmann fold, nad dependent deacetylase, cytoplasm, hydrolase, metal-binding, nad, zinc
Biological sourceThermotoga maritima
Cellular locationCytoplasm : Q9WYW0
Total number of polymer chains2
Total formula weight29283.92
Authors
Hawse, W.F.,Hoff, K.G.,Fatkins, D.,Daines, A.,Zubkova, O.V.,Schramm, V.L.,Zheng, W.,Wolberger, C. (deposition date: 2008-05-22, release date: 2008-09-30, Last modification date: 2023-11-15)
Primary citationHawse, W.F.,Hoff, K.G.,Fatkins, D.G.,Daines, A.,Zubkova, O.V.,Schramm, V.L.,Zheng, W.,Wolberger, C.
Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16:1368-1377, 2008
Cited by
PubMed: 18786399
DOI: 10.1016/j.str.2008.05.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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