PDB: 10097 件ウェブページステータス検索Chemie searchBIRD

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7O6B	Cooperation between the intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly 分子名称: Transcription elongation factor SPT6 著者 Kasiliauskaite, A, Kubicek, K, Klumpler, T, Zanova, M, Zapletal, D, Novacek, J, Stefl, R. 登録日 2021-04-09 公開日 2022-04-20 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Cooperation between intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly. Nucleic Acids Res., 50, 2022
4YYL	Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease 分子名称: 2-(4-fluorophenoxy)-1-(2,3,4-trihydroxyphenyl)ethanone, MANGANESE (II) ION, Polymerase acidic protein, ... 著者 Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Neya, S, Hoshino, T. 登録日 2015-03-24 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.905 Å) 主引用文献 Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase Bioorg.Med.Chem., 23, 2015
4ZI0	Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region without a chelation to the metal ions in the active site 分子名称: 4-{(E)-[2-(4-chlorophenyl)hydrazinylidene]methyl}benzene-1,2,3-triol, MANGANESE (II) ION, Polymerase acidic protein, ... 著者 Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Neya, S, Hoshino, T. 登録日 2015-04-27 公開日 2015-05-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit Biochemistry, 55, 2016
4ZHZ	Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region with expelling one of the metal ions in the active site 分子名称: 5-(2-chlorobenzyl)-2-hydroxy-3-nitrobenzaldehyde, MANGANESE (II) ION, Polymerase acidic protein, ... 著者 Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Neya, S, Hoshino, T. 登録日 2015-04-27 公開日 2015-05-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit Biochemistry, 55, 2016
5JS2	Human Argonaute-2 Bound to a Modified siRNA 分子名称: MAGNESIUM ION, PHENOL, PHOSPHATE ION, ... 著者 Schirle, N.T, MacRae, I.J. 登録日 2016-05-07 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.954 Å) 主引用文献 Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide. J.Am.Chem.Soc., 138, 2016
2Q66	Structure of Yeast Poly(A) Polymerase with ATP and oligo(A) 分子名称: 1,2-ETHANEDIOL, 5'-R(P*AP*AP*AP*AP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Bohm, A, Balbo, P. 登録日 2007-06-04 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mechanism of poly(A) polymerase: structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis. Structure, 15, 2007
5JS1	Human Argonaute2 Bound to an siRNA 分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ... 著者 Schirle, N.T, MacRae, I.J. 登録日 2016-05-07 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.499 Å) 主引用文献 Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide. J.Am.Chem.Soc., 138, 2016
8GW1	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: Helicase, MANGANESE (II) ION, Non-structural protein 7, ... 著者 Yan, L, Rao, Z, Lou, Z. 登録日 2022-09-16 公開日 2023-10-25 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
5ZAL	Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate 分子名称: Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) 著者 Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. 登録日 2018-02-07 公開日 2018-05-09 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
8P7D	CryoEM structure of METTL6 tRNA SerRS complex in a 1:1:2 stoichiometry 分子名称: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Serine tRNA, ... 著者 Throll, P, Dolce, L.G, Kowalinski, E. 登録日 2023-05-30 公開日 2024-06-12 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 31, 2024
8P7C	CryoEM structure of METTL6 tRNA SerRS complex in a 2:2:2 stoichiometry 分子名称: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Serine tRNA, ... 著者 Throll, P, Dolce, L.G, Kowalinski, E. 登録日 2023-05-30 公開日 2024-06-12 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 31, 2024
8P7B	CryoEM structure of METTL6 tRNA SerRS complex in a 1:2:2 stoichiometry 分子名称: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Serine tRNA, ... 著者 Throll, P, Dolce, L.G, Kowalinski, E. 登録日 2023-05-30 公開日 2024-06-12 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (2.42 Å) 主引用文献 Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 31, 2024
6YJ6	Structure of the TFIIIC subcomplex tauA 分子名称: Transcription factor tau 131 kDa subunit, Transcription factor tau 55 kDa subunit, Transcription factor tau 95 kDa subunit,Transcription factor tau 95 kDa subunit 著者 Vorlaender, M.K, Muller, C.W. 登録日 2020-04-02 公開日 2020-09-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the TFIIIC subcomplex tau A provides insights into RNA polymerase III pre-initiation complex formation. Nat Commun, 11, 2020
7ML8	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ001023038 分子名称: 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide, GLUTAMIC ACID, Hexa Vinylpyrrolidone K15, ... 著者 Cuypers, M.G, Slavish, P.J, Yun, M.K, Dubois, R, Rankovic, Z, White, S.W. 登録日 2021-04-27 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with St Jude compound AC067-19 To Be Published
7MX0	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988558 分子名称: 2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-05-17 公開日 2022-05-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988558 To Be Published
3VU7	Crystal structure of REV1-REV7-REV3 ternary complex 分子名称: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Kikuchi, S, Hara, K, Shimizu, T, Sato, M, Hashimoto, H. 登録日 2012-06-20 公開日 2012-08-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of recruitment of DNA polymerase [zeta] by interaction between REV1 and REV7 proteins J.Biol.Chem., 287, 2012
3K59	Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3K5N	Crystal structure of E.coli Pol II-abasic DNA binary complex 分子名称: DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
3K58	Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex 分子名称: DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3K5L	Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
3K57	Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3K5O	Crystal structure of E.coli Pol II 分子名称: DNA polymerase II 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
5FDD	Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0 分子名称: 5-(2-chlorobenzyl)-2-hydroxy-3-nitrobenzaldehyde, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein, ... 著者 Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Hoshino, T. 登録日 2015-12-16 公開日 2015-12-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.506 Å) 主引用文献 Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit Biochemistry, 55, 2016
5OMF	Closed, ternary structure of KOD DNA polymerase 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), ... 著者 Kropp, H.M, Betz, K, Wirth, J, Diederichs, K, Marx, A. 登録日 2017-07-31 公開日 2017-12-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
8E1Q	The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044 分子名称: 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-08-11 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044 To Be Published

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