4YYL
Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease
Summary for 4YYL
Entry DOI | 10.2210/pdb4yyl/pdb |
Descriptor | Polymerase acidic protein, 2-(4-fluorophenoxy)-1-(2,3,4-trihydroxyphenyl)ethanone, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) More |
Total number of polymer chains | 1 |
Total formula weight | 23341.13 |
Authors | Fudo, S.,Yamamoto, N.,Nukaga, M.,Odagiri, T.,Tashiro, M.,Neya, S.,Hoshino, T. (deposition date: 2015-03-24, release date: 2015-04-29, Last modification date: 2023-11-08) |
Primary citation | Fudo, S.,Yamamoto, N.,Nukaga, M.,Odagiri, T.,Tashiro, M.,Neya, S.,Hoshino, T. Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase Bioorg.Med.Chem., 23:5466-5475, 2015 Cited by PubMed: 26252962DOI: 10.1016/j.bmc.2015.07.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.905 Å) |
Structure validation
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