4YYL

Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polymerase acidic protein	polymer	191	22300.5	1	UniProt (P03433)	Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)	RNA-directed RNA polymerase subunit P2
2	B, C, D (A)	2-(4-fluorophenoxy)-1-(2,3,4-trihydroxyphenyl)ethanone	non-polymer		278.2	3	Chemie (4KN)
3	E, F (A)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
4	G (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	H (A)	water	water		18.0	170	Chemie (HOH)

Sequence modifications

A: 1 - 50 (UniProt: P03433)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

A: 73 - 197 (UniProt: P03433)

PDB	External Database	Details
Ala 51	-	linker
Ser 52	-	linker
Ala 198	-	expression tag
Ala 199	-	expression tag
Glu 200	-	expression tag
Leu 201	-	expression tag
Ala 202	-	expression tag
Leu 203	-	expression tag
Val 204	-	expression tag
Pro 205	-	expression tag
Arg 206	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22300.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1040.6
All*	Total formula weight	23341.1

*Water molecules are not included.