4YYL
Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 4KN A 301 |
| Chain | Residue |
| A | TYR24 |
| A | LYS134 |
| A | 4KN302 |
| A | MN304 |
| A | MN305 |
| A | HOH433 |
| A | HIS41 |
| A | GLU80 |
| A | ARG84 |
| A | PHE105 |
| A | LEU106 |
| A | ASP108 |
| A | GLU119 |
| A | ILE120 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue 4KN A 302 |
| Chain | Residue |
| A | THR20 |
| A | GLU26 |
| A | LYS34 |
| A | ALA37 |
| A | ILE38 |
| A | HIS41 |
| A | GLY121 |
| A | VAL122 |
| A | TYR130 |
| A | 4KN301 |
| A | 4KN303 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue 4KN A 303 |
| Chain | Residue |
| A | GLU31 |
| A | LYS34 |
| A | ALA37 |
| A | ARG124 |
| A | PHE150 |
| A | PHE191 |
| A | SER194 |
| A | GLU195 |
| A | 4KN302 |
| A | HOH407 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 304 |
| Chain | Residue |
| A | HIS41 |
| A | ASP108 |
| A | GLU119 |
| A | ILE120 |
| A | 4KN301 |
| A | MN305 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 305 |
| Chain | Residue |
| A | GLU80 |
| A | ASP108 |
| A | 4KN301 |
| A | MN304 |
| A | HOH433 |
| A | HOH455 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | ARG124 |
| A | ARG179 |
| A | TRP188 |
| A | ARG192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 15 |
| Details | Motif: {"description":"Nuclear localization signal 1 (NLS1)","evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8113737","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26252962","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27088785","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YYL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZQQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27088785","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YYL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZQQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
