PDB: 2862 件ウェブページステータス検索Chemie searchBIRD

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6XOH	Structure of SUMO1-ML00789344 adduct bound to SAE 分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... 著者 Sintchak, M, Lane, W, Bump, N. 登録日 2020-07-07 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.226 Å) 主引用文献 Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J.Med.Chem., 64, 2021
6XOI	Structure of SUMO1-ML00752641 adduct bound to SAE 分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... 著者 Sintchak, M, Lane, W, Bump, N. 登録日 2020-07-07 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J.Med.Chem., 64, 2021
1KSZ	ENTRAPMENT OF 6-THIOPHOSPHORYL-IMP IN THE ACTIVE SITE OF CRYSTALLINE ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI, DATA COLLECTED AT 298K 分子名称: 2-DEAZO-6-THIOPHOSPHATE GUANOSINE-5'-MONOPHOSPHATE, ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Poland, B.W, Bruns, C.A, Fromm, H.J, Honzatko, R.B. 登録日 1997-01-14 公開日 1997-10-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Entrapment of 6-thiophosphoryl-IMP in the active site of crystalline adenylosuccinate synthetase from Escherichia coli. J.Biol.Chem., 272, 1997
4V8P	T.thermophila 60S ribosomal subunit in complex with initiation factor 6. 分子名称: 26S RRNA, 5.8S RRNA, 5S RRNA, ... 著者 Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N. 登録日 2011-09-14 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6. Science, 334, 2011
6ENY	Structure of the human PLC editing module 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ... 著者 Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R. 登録日 2017-10-07 公開日 2017-11-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structure of the human MHC-I peptide-loading complex. Nature, 551, 2017
6Z6L	Cryo-EM structure of human CCDC124 bound to 80S ribosomes 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6ZM7	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-01 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZME	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-02 公開日 2020-08-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6Z6N	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6Z6M	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6ZMI	SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-02 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZMO	SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-03 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
4W5V	Crystal structure of Human SUMO E2-conjugating enzyme (Ubc9) in complex with E1-activating enzyme (Uba2) ubiquitin fold domain (Ufd) 分子名称: FORMIC ACID, GLYCEROL, POTASSIUM ION, ... 著者 Boucher, L.E, Reiter, K.H, Matunis, M.J, Bosch, J. 登録日 2014-08-19 公開日 2015-09-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human SUMO complex To Be Published
4UG0	STRUCTURE OF THE HUMAN 80S RIBOSOME 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... 著者 Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. 登録日 2015-03-20 公開日 2015-06-10 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the human 80S ribosome NATURE, 520, 2015
6O83	S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, ... 著者 Hann, Z.S, Lima, C.D. 登録日 2019-03-08 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Structural basis for adenylation and thioester bond formation in the ubiquitin E1. Proc.Natl.Acad.Sci.USA, 116, 2019
6Y57	Structure of human ribosome in hybrid-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-25 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
6Y2L	Structure of human ribosome in POST state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-16 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
6Y0G	Structure of human ribosome in classical-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-07 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
4V8Y	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex 分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... 著者 Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. 登録日 2013-07-20 公開日 2014-07-09 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
2E18	Crystal structure of project PH0182 from Pyrococcus horikoshii OT3 分子名称: IMIDAZOLE, NH(3)-dependent NAD(+) synthetase, ZINC ION 著者 Shimizu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-10-18 公開日 2007-04-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of project PH0182 from Pyrococcus horikoshii OT3 To be Published
6OPC	Cdc48 Hexamer in a complex with substrate and Shp1(Ubx Domain) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... 著者 Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. 登録日 2019-04-24 公開日 2019-07-10 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
6EPC	Ground state 26S proteasome (GS2) 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... 著者 Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (12.3 Å) 主引用文献 In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6EPD	Substrate processing state 26S proteasome (SPS1) 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... 著者 Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (15.4 Å) 主引用文献 In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
5AZF	Crystal structure of LGG-1 complexed with a WEEL peptide 分子名称: CADMIUM ION, Protein lgg-1, SULFATE ION, ... 著者 Watanabe, Y, Noda, N.N. 登録日 2015-10-05 公開日 2015-12-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
6LSR	Cryo-EM structure of a pre-60S ribosomal subunit - state B 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. 登録日 2020-01-20 公開日 2020-08-26 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020

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