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1Z2N
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Inositol 1,3,4-trisphosphate 5/6-kinase complexed Mg2+/ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, inositol 1,3,4-trisphosphate 5/6-kinase
著者Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H.
登録日2005-03-08
公開日2005-04-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.
Mol.Cell, 18, 2005
4A7L
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Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1)
分子名称: ACTIN, ALPHA SKELETON MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S.
登録日2011-11-14
公開日2012-08-01
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
4E0T
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Crystal structure of CdpNPT in its unbound state
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cyclic dipeptide N-prenyltransferase, ...
著者Schuller, J.M, Zocher, G, Stehle, T.
登録日2012-03-05
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity.
J.Mol.Biol., 422, 2012
2OIP
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BU of 2oip by Molmil
Crystal Structure of the S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Chain A, ...
著者Martucci, W.E, Vargo, M.A.
登録日2007-01-11
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis
Biochemistry, 46, 2007
4E0U
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Crystal structure of CdpNPT in complex with thiolodiphosphate and (S)-benzodiazependione
分子名称: (3S)-3-(1H-indol-3-ylmethyl)-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 1,2-ETHANEDIOL, Cyclic dipeptide N-prenyltransferase, ...
著者Schuller, J.M, Zocher, G, Stehle, T.
登録日2012-03-05
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity.
J.Mol.Biol., 422, 2012
4ZXT
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Complex of ERK2 with catechol
分子名称: AMMONIUM ION, CATECHOL, Mitogen-activated protein kinase 1, ...
著者Kurinov, I, Malakhova, M.
登録日2015-05-20
公開日2016-05-25
最終更新日2016-10-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer.
Oncotarget, 7, 2016
4A7N
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Structure of bare F-actin filaments obtained from the same sample as the Actin-Tropomyosin-Myosin Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, F-ACTIN
著者Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S.
登録日2011-11-14
公開日2012-08-01
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
4N9L
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crystal structure of beta-lactamse PenP_E166S in complex with meropenem
分子名称: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase
著者Pan, X, Wong, W, Zhao, Y.
登録日2013-10-21
公開日2014-09-10
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
1GWZ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1
分子名称: SHP-1
著者Yang, J, Liang, X, Niu, T, Meng, W, Zhao, Z, Zhou, G.W.
登録日1998-08-22
公開日1999-08-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 273, 1998
1ADG
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CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN
分子名称: ALCOHOL DEHYDROGENASE, BETA-METHYLENE-SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ZINC ION
著者Li, H, Hallows, W.A, Punzi, J.S, Marquez, V.E, Carrell, H.L, Pankiewicz, K.W, Watanabe, K.A, Goldstein, B.M.
登録日1993-10-18
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
Biochemistry, 33, 1994
1ZIG
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BU of 1zig by Molmil
GAGA RNA TETRALOOP, NMR, 10 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*GP*CP*GP*AP*GP*AP*GP*CP*CP*U)-3')
著者Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
登録日1996-07-27
公開日1997-03-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
1ZIH
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GCAA RNA TETRALOOP, NMR, 10 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*GP*CP*GP*CP*AP*AP*GP*CP*CP*U)-3')
著者Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
登録日1996-07-27
公開日1997-03-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
5E9Y
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BU of 5e9y by Molmil
Crystal Structure of BAZ2B bromodomain in complex with MPD
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B
著者Lolli, G, Caflisch, A.
登録日2015-10-15
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography.
Acs Chem.Biol., 11, 2016
4A7H
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BU of 4a7h by Molmil
Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)
分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S.
登録日2011-11-14
公開日2012-08-01
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
5DYU
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BU of 5dyu by Molmil
Crystal Structure of BAZ2B bromodomain in complex with fragment F39
分子名称: 1H-imidazol-5-ylmethanol, Bromodomain adjacent to zinc finger domain protein 2B
著者Lolli, G, Caflisch, A.
登録日2015-09-25
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography.
Acs Chem.Biol., 11, 2016
6WN0
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BU of 6wn0 by Molmil
The structure of a CoA-dependent acyl-homoserine lactone synthase, RpaI, with the adduct of SAH and p-coumaroyl CoA
分子名称: (2S)-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)-2-{[(2E)-3-(cis-4-hydroxycyclohexa-2,5-dien-1-yl)prop-2-enoyl]amino}butanoic acid, 4-coumaroyl-homoserine lactone synthase, COENZYME A
著者Dong, S.-H, Nair, S.K.
登録日2020-04-22
公開日2020-05-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-Guided Biochemical Analysis of Quorum Signal Synthase Specificities.
Acs Chem.Biol., 15, 2020
4ZPE
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BU of 4zpe by Molmil
BACE1 in complex with 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
分子名称: 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-[3-(propan-2-yloxy)benzyl]-1,3,8-triazaspiro[4.5]dec-3-en-2-one, Beta-secretase 1
著者Orth, P.
登録日2015-05-07
公開日2015-08-05
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Methyl-substitution of an iminohydantoin spiropiperidine beta-secretase (BACE-1) inhibitor has a profound effect on its potency.
Bioorg.Med.Chem.Lett., 25, 2015
3N85
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BU of 3n85 by Molmil
Crystallographic trimer of HER2 extracellular regions in complex with tryptophan-rich antibody fragment
分子名称: CHLORIDE ION, Fab37 Heavy Chain, Fab37 Light Chain, ...
著者Eigenbrot, C.
登録日2010-05-27
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the complex between HER2 and an antibody paratope formed by side chains from tryptophan and serine.
J.Mol.Biol., 402, 2010
4DRJ
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BU of 4drj by Molmil
o-crystal structure of the PPIase domain of FKBP52, Rapamycin and the FRB fragment of mTOR
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP4, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, SULFATE ION, ...
著者Maerz, A.M, Bracher, A, Hausch, F.
登録日2012-02-17
公開日2013-02-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
Mol.Cell.Biol., 33, 2013
1Z2P
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Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with Mg2+/AMP-PCP/Ins(1,3,4)P3
分子名称: (1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H.
登録日2005-03-08
公開日2005-04-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.
Mol.Cell, 18, 2005
4JH4
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Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin
分子名称: FOSFOMYCIN, Metallothiol transferase FosB, NICKEL (II) ION
著者Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N.
登録日2013-03-04
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus.
Biochemistry, 52, 2013
4JH3
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Crystal Structure of FosB from Bacillus cereus with Zinc and Fosfomycin
分子名称: FORMIC ACID, FOSFOMYCIN, GLYCEROL, ...
著者Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N.
登録日2013-03-04
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus.
Biochemistry, 52, 2013
7Y8R
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BU of 7y8r by Molmil
The nucleosome-bound human PBAF complex
分子名称: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2, ...
著者Wang, L, Yu, J, Yu, Z, Wang, Q, He, S, Xu, Y.
登録日2022-06-24
公開日2022-12-07
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure of nucleosome-bound human PBAF complex.
Nat Commun, 13, 2022
1ZIF
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BU of 1zif by Molmil
GAAA RNA TETRALOOP, NMR, 10 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*GP*CP*GP*AP*AP*AP*GP*CP*CP*U)-3')
著者Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
登録日1996-07-27
公開日1997-03-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
3CMW
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BU of 3cmw by Molmil
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), MAGNESIUM ION, ...
著者Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008

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