3N85
Crystallographic trimer of HER2 extracellular regions in complex with tryptophan-rich antibody fragment
Summary for 3N85
Entry DOI | 10.2210/pdb3n85/pdb |
Related | 1IVO 1MOX 1N8Z 1S78 1ZA3 3I2T |
Descriptor | Receptor tyrosine-protein kinase erbB-2, Fab37 Light Chain, Fab37 Heavy Chain, ... (7 entities in total) |
Functional Keywords | her2, erbb2, trp/ser library, phage display, transferase-immune system complex, transferase/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 119434.93 |
Authors | Eigenbrot, C. (deposition date: 2010-05-27, release date: 2010-07-28, Last modification date: 2023-09-06) |
Primary citation | Fisher, R.D.,Ultsch, M.,Lingel, A.,Schaefer, G.,Shao, L.,Birtalan, S.,Sidhu, S.S.,Eigenbrot, C. Structure of the complex between HER2 and an antibody paratope formed by side chains from tryptophan and serine. J.Mol.Biol., 402:217-229, 2010 Cited by PubMed: 20654626DOI: 10.1016/j.jmb.2010.07.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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