1IVO

Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains.

Summary for 1IVO

Related1JL9
DescriptorEpidermal Growth Factor Receptor, Epidermal growth factor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordstransmembrane, glycoprotein, receptor, riken structural genomics/proteomics initiative, rsgi, structural genomics, transferase-signaling protein complex, transferase/signaling protein
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight152212.78
Authors
Ogiso, H.,Ishitani, R.,Nureki, O.,Fukai, S.,Yamanaka, M.,Kim, J.H.,Saito, K.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2002-03-28, release date: 2002-10-16, Last modification date: 2020-07-29)
Primary citation
Ogiso, H.,Ishitani, R.,Nureki, O.,Fukai, S.,Yamanaka, M.,Kim, J.H.,Saito, K.,Inoue, M.,Shirouzu, M.,Yokoyama, S.
Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains.
Cell(Cambridge,Mass.), 110:775-787, 2002
PubMed: 12297050 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(02)00963-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers46 8.9% 9.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02