3N85
Crystallographic trimer of HER2 extracellular regions in complex with tryptophan-rich antibody fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Receptor tyrosine-protein kinase erbB-2 | polymer | 624 | 68794.1 | 1 | UniProt (P04626) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) In PDB | Homo sapiens (human) | p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, Tyrosine kinase-type cell surface receptor HER2, Metastatic lymph node gene 19 protein, MLN 19 |
| 2 | L | Fab37 Light Chain | polymer | 217 | 23897.5 | 1 | Homo sapiens | ||
| 3 | H | Fab37 Heavy Chain | polymer | 224 | 23851.7 | 1 | Homo sapiens | ||
| 4 | B | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 5 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | A, L, H | SULFATE ION | non-polymer | 96.1 | 16 | Chemie (SO4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 116543.2 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1319.2 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1572.5 | |
| All* | Total formula weight | 119434.9 |
