PDB: 73050 件ウェブページステータス検索Chemie searchBIRD

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4E8U	Crystal structure of Arabidopsis IDN2 XS domain along with a small segment of adjacent coiled-coil region 分子名称: Putative uncharacterized protein T8P19.180, SULFATE ION 著者 Simanshu, D.K, Patel, D.J. 登録日 2012-03-20 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis. Proc.Natl.Acad.Sci.USA, 109, 2012
3QIO	Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor 分子名称: 3-hydroxy-6-(phenylsulfonyl)quinazoline-2,4(1H,3H)-dione, Gag-Pol polyprotein,Ribonuclease HI,Gag-Pol polyprotein, MANGANESE (II) ION, ... 著者 Lansdon, E.B, Liu, Q. 登録日 2011-01-27 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4011 Å) 主引用文献 Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors. Antimicrob.Agents Chemother., 55, 2011
4KPN	Plant nucleoside hydrolase - PpNRh1 enzyme 分子名称: CALCIUM ION, Nucleoside N-ribohydrolase 1 著者 Morera, S, Vigouroux, A, Kopecny, D. 登録日 2013-05-14 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structure and Function of Nucleoside Hydrolases from Physcomitrella patens and Maize Catalyzing the Hydrolysis of Purine, Pyrimidine, and Cytokinin Ribosides. Plant Physiol., 163, 2013
4K6U	Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386 分子名称: 3,3',3''-[nitrilotris(methanediyl-1H-1,2,3-triazole-4,1-diyl)]tripropan-1-ol, ACETATE ION, Fiber protein, ... 著者 Stehle, T, Bauer, J. 登録日 2013-04-16 公開日 2014-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells. Org.Biomol.Chem., 13, 2015
4EJX	Structure of ceruloplasmin-myeloperoxidase complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Ceruloplasmin, ... 著者 Samygina, V.R, Sokolov, A.V, Bourenkov, G, Vasilyev, V.B, Bartunik, H. 登録日 2012-04-07 公開日 2013-04-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.69 Å) 主引用文献 Ceruloplasmin: macromolecular assemblies with iron-containing acute phase proteins. Plos One, 8, 2013
3QQ8	Crystal structure of p97-N in complex with FAF1-UBX 分子名称: CHLORIDE ION, FAS-associated factor 1, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2011-02-15 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Hierarchical Binding of Cofactors to the AAA ATPase p97. Structure, 19, 2011
3Q61	3'-Fluoro Hexitol Nucleic Acid DNA Structure 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(F3H)P*AP*CP*GP*C)-3') 著者 Seth, P.R, Allerson, C.R, Prakash, T.P, Siwkowski, A, Berdeja, A, Yu, J, Pallan, P.S, Watt, A.T, Gaus, H, Bhat, B, Egli, M, Swayze, E.E. 登録日 2010-12-30 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides. J.Am.Chem.Soc., 133, 2011
4K9B	Structure of Ternary Complex of cGAS with dsDNA and Bound c[G(2 ,5 )pA(3 ,5 )p] 分子名称: ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
4ERF	crystal structure of MDM2 (17-111) in complex with compound 29 (AM-8553) 分子名称: E3 ubiquitin-protein ligase Mdm2, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl}acetic acid 著者 Huang, X. 登録日 2012-04-20 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design of novel inhibitors of the MDM2-p53 interaction. J.Med.Chem., 55, 2012
4KDD	Structure of Mycobacterium tuberculosis ribosome recycling factor in presence of detergent 分子名称: CADMIUM ION, DECYL-BETA-D-MALTOPYRANOSIDE, Ribosome-recycling factor 著者 Selvaraj, M, Govindan, A, Seshadri, A, Dubey, B, Varshney, U, Vijayan, M. 登録日 2013-04-24 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular flexibility of Mycobacterium tuberculosis ribosome recycling factor and its functional consequences: an exploration involving mutants. J.Biosci., 38, 2013
4EGJ	Crystal structure of D-alanine-D-alanine ligase from Burkholderia xenovorans 分子名称: D-alanine--D-alanine ligase 著者 SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-31 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3RTM	Structure of Bace-1 (Beta-Secretase) in Complex with 3-(2-Aminoquinolin-3-yl)-N-cyclohexyl-N-methylpropanamide 分子名称: 3-(2-aminoquinolin-3-yl)-N-cyclohexyl-N-methylpropanamide, Beta-secretase 1, GLYCEROL, ... 著者 Sickmier, E.A. 登録日 2011-05-03 公開日 2011-08-31 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1). J.Med.Chem., 54, 2011
3R2B	MK2 kinase bound to Compound 5b 分子名称: 2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one, MAP kinase-activated protein kinase 2 著者 Oubrie, A, van Zeeland, M, Versteegh, J. 登録日 2011-03-14 公開日 2011-05-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-based lead identification of ATP-competitive MK2 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3RU1	Structure of Bace-1 (Beta-Secretase) in Complex with 3-(2-Aminoquinolin-3-yl)-N-(cyclohexylmethyl)propanamide 分子名称: 3-(2-aminoquinolin-3-yl)-N-(cyclohexylmethyl)propanamide, Beta-secretase 1, GLYCEROL, ... 著者 Sickmier, E.A. 登録日 2011-05-04 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1). J.Med.Chem., 54, 2011
4LQC	The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry. 分子名称: TcpB 著者 Snyder, G.A, Smith, P, Fresquez, T, Cirl, C, Jiang, J, Snyder, N, Luchetti, T, Miethke, T, Xiao, T.S. 登録日 2013-07-17 公開日 2013-12-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. J.Biol.Chem., 289, 2014
3U6C	MutM set 1 ApGo 分子名称: DNA (5'-D(*GP*GP*TP*AP*GP*AP*TP*CP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*CP*AP*(8OG)P*GP*AP*(TX)P*CP*TP*AP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... 著者 Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. 登録日 2011-10-12 公開日 2012-04-25 最終更新日 2013-09-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
4GMX	Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-08-16 公開日 2012-10-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood, 120, 2012
4LOW	Structure and identification of a pterin dehydratase-like protein as a RuBisCO assembly factor in the alpha-carboxysome 分子名称: FORMIC ACID, NICKEL (II) ION, acRAF 著者 Wheatley, N.M, Gidaniyan, S.D, Cascio, D, Yeates, T.O. 登録日 2013-07-13 公開日 2013-09-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure and Identification of a Pterin Dehydratase-like Protein as a Ribulose-bisphosphate Carboxylase/Oxygenase (RuBisCO) Assembly Factor in the alpha-Carboxysome. J.Biol.Chem., 289, 2014
3TRR	Crystal structure of a probable enoyl-CoA hydratase/isomerase from Mycobacterium abscessus 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3TLS	The GLIC pentameric Ligand-Gated Ion Channel E19'P mutant in a locally-closed conformation (LC2 subtype) 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-08-30 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3RBS	Crystal structure of the myomesin domains 10 and 11 分子名称: BETA-MERCAPTOETHANOL, Myomesin-1, NITRATE ION 著者 Chatziefthimiou, S.D, Pinotsis, N, Wilmanns, M. 登録日 2011-03-29 公開日 2012-03-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Superhelical architecture of the Myosin filament-linking protein myomesin with unusual elastic properties. Plos Biol., 10, 2012
4K6V	Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407 分子名称: 3,3',3''-[nitrilotris(methanediyl-1H-1,2,3-triazole-4,1-diyl)]tripropan-1-ol, 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ACETATE ION, ... 著者 Stehle, T, Bauer, J. 登録日 2013-04-16 公開日 2014-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells. Org.Biomol.Chem., 13, 2015
3U6P	MutM set 1 GpG 分子名称: DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*CP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*GP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... 著者 Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. 登録日 2011-10-12 公開日 2012-04-25 最終更新日 2013-09-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
3RKQ	NKX2.5 Homeodomain dimer bound to ANF-242 DNA 分子名称: ANF-242 DNA, Homeobox protein Nkx-2.5, MAGNESIUM ION 著者 Genis, C, Scone, P, Kasahara, H, Nam, H.-J. 登録日 2011-04-18 公開日 2012-05-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the human NKX2.5 homeodomain in complex with DNA target. Biochemistry, 51, 2012
4K8O	CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Antigen peptide transporter 1, CITRIC ACID, ... 著者 Vakkasoglu, A.S, Grossmann, N, Hulpke, S, Abele, R, Tampe, R, Gaudet, R. 登録日 2013-04-18 公開日 2014-09-03 最終更新日 2014-12-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Nat Commun, 5, 2014

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