4K6V

Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407

Summary for 4K6V

Entry DOI	10.2210/pdb4k6v/pdb
Related	1UXE 3N0I 3QND 4K6T 4K6U 4K6W
Descriptor	Fiber protein, ZINC ION, 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ... (8 entities in total)
Functional Keywords	adenovirus, fiber knob, protein carbohydrate interaction, carbohydrate mimic, multivalent ligand, viral protein
Biological source	Human adenovirus 37
Total number of polymer chains	3
Total formula weight	67115.74
Authors	Stehle, T.,Bauer, J. (deposition date: 2013-04-16, release date: 2014-10-22, Last modification date: 2024-04-03)
Primary citation	Caraballo, R.,Saleeb, M.,Bauer, J.,Liaci, A.M.,Chandra, N.,Storm, R.J.,Frangsmyr, L.,Qian, W.,Stehle, T.,Arnberg, N.,Elofsson, M. Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells. Org.Biomol.Chem., 13:9194-9205, 2015 Cited by PubMed: 26177934 DOI: 10.1039/c5ob01025j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation