3RKQ
NKX2.5 Homeodomain dimer bound to ANF-242 DNA
Summary for 3RKQ
Entry DOI | 10.2210/pdb3rkq/pdb |
Descriptor | Homeobox protein Nkx-2.5, ANF-242 DNA, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | helix-turn-helix, dna binding, nucleus, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Probable): P52952 |
Total number of polymer chains | 4 |
Total formula weight | 25934.38 |
Authors | Genis, C.,Scone, P.,Kasahara, H.,Nam, H.-J. (deposition date: 2011-04-18, release date: 2012-05-09, Last modification date: 2024-02-28) |
Primary citation | Pradhan, L.,Genis, C.,Scone, P.,Weinberg, E.O.,Kasahara, H.,Nam, H.J. Crystal structure of the human NKX2.5 homeodomain in complex with DNA target. Biochemistry, 51:6312-6319, 2012 Cited by PubMed: 22849347DOI: 10.1021/bi300849c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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