3RKQ
NKX2.5 Homeodomain dimer bound to ANF-242 DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Homeobox protein Nkx-2.5 | polymer | 58 | 7129.3 | 2 | UniProt (P52952) Pfam (PF00046) | Homo sapiens (human) | Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E |
| 2 | C (C) | ANF-242 DNA | polymer | 19 | 5916.8 | 1 | |||
| 3 | D (D) | ANF-242 DNA | polymer | 19 | 5734.7 | 1 | |||
| 4 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, B: 138 - 194 (UniProt: P52952)
| PDB | External Database | Details |
|---|---|---|
| Gly 137 | - | expression tag |
| Ser 193 | Cys 193 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 25910.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 25934.4 |
