5KSR
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![BU of 5ksr by Molmil](/molmil-images/mine/5ksr) | Stationary phase survival protein E (SurE) from Xylella fastidiosa - XFSurE-TB (Tetramer Bigger). | 分子名称: | 5'-nucleotidase SurE, CHLORIDE ION, IODIDE ION, ... | 著者 | Machado, A.T.P, Fonseca, E.M.B, Dos Reis, M.A, Saraiva, A.M, Dos Santos, C.A, De Toledo, M.A, Polikarpov, I, De Souza, A.P, De Aparicio, R, Iulek, J. | 登録日 | 2016-07-09 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X-ray scattering studies, and normal mode analysis. Proteins, 85, 2017
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6EPL
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![BU of 6epl by Molmil](/molmil-images/mine/6epl) | Ras guanine exchange factor SOS1 (Rem-cdc25) in complex with KRAS(G12C) | 分子名称: | GLYCEROL, GTPase KRas, Son of sevenless homolog 1 | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Bader, B, Schroeder, J, Wortmann, L, Sautier, B, Briem, H, Petersen, K, Badock, V. | 登録日 | 2017-10-12 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6EPO
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![BU of 6epo by Molmil](/molmil-images/mine/6epo) | RAS GUANINE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH KRAS(G12C) AND FRAGMENT SCREENING HIT F3 | 分子名称: | 3-(4-chlorophenyl)propan-1-amine, GLYCEROL, GTPase KRas, ... | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Bader, B, Schroeder, J, Wortmann, L, Sautier, B, Kahmann, J, Wegener, D, Briem, H, Petersen, K, Badock, V. | 登録日 | 2017-10-12 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6LN4
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![BU of 6ln4 by Molmil](/molmil-images/mine/6ln4) | Estrogen-related receptor beta(ERR2) in complex with PGC1a-2a | 分子名称: | 10-mer from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Steroid hormone receptor ERR2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2019-12-28 | 公開日 | 2020-10-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor beta. J.Mol.Biol., 432, 2020
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5A89
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![BU of 5a89 by Molmil](/molmil-images/mine/5a89) | Crystal structure of the riboflavin kinase module of FAD synthetase from Corynebacterium ammoniagenes in complex with FMN and ADP(P 21 21 21) | 分子名称: | ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... | 著者 | Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Medina, M. | 登録日 | 2015-07-13 | 公開日 | 2015-12-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights Into the Synthesis of Fmn in Prokaryotic Organisms. Acta Crystallogr.,Sect.D, 71, 2015
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6EM9
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![BU of 6em9 by Molmil](/molmil-images/mine/6em9) | S.aureus ClpC resting state, asymmetric map | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpC | 著者 | Carroni, M, Mogk, A, Bukau, B, Franke, K. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
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7AO2
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![BU of 7ao2 by Molmil](/molmil-images/mine/7ao2) | Crystal structure of CotB2 variant W288G in complex with alendronate | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, CHLORIDE ION, ... | 著者 | Dimos, N, Driller, R, Loll, B. | 登録日 | 2020-10-13 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142, 2020
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4WKM
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![BU of 4wkm by Molmil](/molmil-images/mine/4wkm) | AmpR effector binding domain from Citrobacter freundii bound to UDP-MurNAc-pentapeptide | 分子名称: | ALA-FGA-API-DAL-DAL, GLYCEROL, LysR family transcriptional regulator, ... | 著者 | Vadlamani, G, Reeve, T.M, Mark, B.L. | 登録日 | 2014-10-02 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The beta-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP-N-acetylmuramic Acid (MurNAc)-pentapeptide. J.Biol.Chem., 290, 2015
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6E67
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![BU of 6e67 by Molmil](/molmil-images/mine/6e67) | Structure of beta2 adrenergic receptor fused to a Gs peptide | 分子名称: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera | 著者 | Liu, X, Xu, X, Hilger, D, Tiemann, J, Liu, H, Du, Y, Hirata, K, Sun, X, Guixa-Gonzalez, R, Mathiesen, J, Hildebrand, P, Kobilka, B. | 登録日 | 2018-07-24 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural Insights into the Process of GPCR-G Protein Complex Formation. Cell, 177, 2019
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1B7A
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![BU of 1b7a by Molmil](/molmil-images/mine/1b7a) | STRUCTURE OF THE PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN FROM BOVINE BRAIN | 分子名称: | PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER | 著者 | Serre, L, Vallee, B, Bureaud, N, Schoentgen, F, Zelwer, C. | 登録日 | 1999-01-21 | 公開日 | 1999-01-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of the phosphatidylethanolamine-binding protein from bovine brain: a novel structural class of phospholipid-binding proteins. Structure, 6, 1998
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5E0T
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![BU of 5e0t by Molmil](/molmil-images/mine/5e0t) | |
8PB5
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![BU of 8pb5 by Molmil](/molmil-images/mine/8pb5) | PsiM in complex with sinefungin and norbaeocystin | 分子名称: | CHLORIDE ION, Norbaeocystin, Psilocybin synthase, ... | 著者 | Werten, S, Hudspeth, J, Rupp, B. | 登録日 | 2023-06-08 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | Methyl transfer in psilocybin biosynthesis. Nat Commun, 15, 2024
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8PB4
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![BU of 8pb4 by Molmil](/molmil-images/mine/8pb4) | PsiM in complex with SAH and norbaeocystin, orthorhombic crystal form | 分子名称: | CHLORIDE ION, Norbaeocystin, Psilocybin synthase, ... | 著者 | Werten, S, Hudspeth, J, Rupp, B. | 登録日 | 2023-06-08 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (0.91 Å) | 主引用文献 | Methyl transfer in psilocybin biosynthesis. Nat Commun, 15, 2024
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8PB6
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![BU of 8pb6 by Molmil](/molmil-images/mine/8pb6) | PsiM in complex with SAH and baeocystin | 分子名称: | Baeocystin, CHLORIDE ION, Psilocybin synthase, ... | 著者 | Werten, S, Hudspeth, J, Rupp, B. | 登録日 | 2023-06-08 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (0.93 Å) | 主引用文献 | Methyl transfer in psilocybin biosynthesis. Nat Commun, 15, 2024
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7AO5
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![BU of 7ao5 by Molmil](/molmil-images/mine/7ao5) | Crystal structure of CotB2 variant W288F | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION | 著者 | Dimos, N, Driller, R, Loll, B. | 登録日 | 2020-10-13 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142, 2020
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4PGP
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![BU of 4pgp by Molmil](/molmil-images/mine/4pgp) | CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM DESULFOVIBRIO ALASKENSIS G20 (Dde_0634, TARGET EFI-510120) WITH BOUND 3-INDOLE ACETIC ACID | 分子名称: | 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, Extracellular solute-binding protein, ... | 著者 | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-05-02 | 公開日 | 2014-06-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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7JT5
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7AHH
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![BU of 7ahh by Molmil](/molmil-images/mine/7ahh) | OpuA inhibited inward-facing, SBD docked | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ... | 著者 | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | 登録日 | 2020-09-24 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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7AO3
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![BU of 7ao3 by Molmil](/molmil-images/mine/7ao3) | Crystal structure of CotB2 variant F149L in complex with alendronate | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, CHLORIDE ION, ... | 著者 | Dimos, N, Driller, R, Loll, B. | 登録日 | 2020-10-13 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142, 2020
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8PB7
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![BU of 8pb7 by Molmil](/molmil-images/mine/8pb7) | PsiM in complex with sinefungin and baeocystin | 分子名称: | Baeocystin, CHLORIDE ION, Psilocybin synthase, ... | 著者 | Werten, S, Hudspeth, J, Rupp, B. | 登録日 | 2023-06-08 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | 主引用文献 | Methyl transfer in psilocybin biosynthesis. Nat Commun, 15, 2024
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5E9D
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8ENR
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![BU of 8enr by Molmil](/molmil-images/mine/8enr) | |
5I2E
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![BU of 5i2e by Molmil](/molmil-images/mine/5i2e) | Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound Sulfamate Inhibitor 3a:3-(5-O-{[3-(1H-indol-3-yl)propanoyl]sulfamoyl}-beta-D-ribofuranosyl)-3H-imidazo[2,1-i]purine | 分子名称: | 3-(5-O-{[3-(1H-indol-3-yl)propanoyl]sulfamoyl}-beta-D-ribofuranosyl)-3H-imidazo[2,1-i]purine, GLYCEROL, Histidine triad nucleotide-binding protein 1 | 著者 | Strom, A.M, Finzel, B.C, Wagner, C.R. | 登録日 | 2016-02-08 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. Acs Med.Chem.Lett., 7, 2016
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3HJI
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7AHE
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![BU of 7ahe by Molmil](/molmil-images/mine/7ahe) | OpuA inhibited inward facing | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component | 著者 | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | 登録日 | 2020-09-24 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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