PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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3NBB	Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha 分子名称: COPPER (II) ION, Peroxisomal primary amine oxidase 著者 Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. 登録日 2010-06-03 公開日 2010-08-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity. Biochemistry, 49, 2010
3ZBX	X-ray Structure of c-Met kinase in complex with inhibitor 6-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl) quinoline. 分子名称: 6-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline, HEPATOCYTE GROWTH FACTOR RECEPTOR 著者 McTigue, M, Wickersham, J, Ryan, K. 登録日 2012-11-13 公開日 2013-11-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Lessons from (S)-6-(1-(6-(1-Methyl-1H-Pyrazol-4-Yl)-[1,2, 4]Triazolo[4,3-B]Pyridazin-3-Yl)Ethyl)Quinoline (Pf-04254644), an Inhibitor of Receptor Tyrosine Kinase C-met with High Protein Kinase Selectivity But Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats. J.Med.Chem., 56, 2013
3ZFG	Human enterovirus 71 in complex with capsid binding inhibitor WIN51711 分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ... 著者 Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G. 登録日 2012-12-11 公開日 2013-03-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor. Proc.Natl.Acad.Sci.USA, 110, 2013
3PM1	Structure of QacR E90Q bound to Ethidium 分子名称: ETHIDIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Schumacher, M.A. 登録日 2010-11-15 公開日 2011-07-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity. Plos One, 6, 2011
3PMG	STRUCTURE OF RABBIT MUSCLE PHOSPHOGLUCOMUTASE AT 2.4 ANGSTROMS RESOLUTION. USE OF FREEZING POINT DEPRESSANT AND REDUCED TEMPERATURE TO ENHANCE DIFFRACTIVITY 分子名称: MAGNESIUM ION, Phosphoglucomutase-1 著者 Ray Junior, W.J, Liu, Y, Baranidharan, S. 登録日 1995-03-02 公開日 1995-12-07 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution. Acta Crystallogr.,Sect.D, 53, 1997
2UZA	CRYSTAL STRUCTURE OF THE FREE RADICAL INTERMEDIATE OF PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM DESULFOVIBRIO AFRICANUS 分子名称: 2-ACETYL-THIAMINE DIPHOSPHATE, CALCIUM ION, CARBON DIOXIDE, ... 著者 Chabriere, E, Cavazza, C, Contreras-Martel, C, Fontecilla-Camps, J.C. 登録日 2007-04-27 公開日 2008-05-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate. Structure, 14, 2006
3ZC5	X-ray Structure of c-Met kinase in complex with inhibitor (S)-6-(1-(6- (1-methyl-1H-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)ethyl) quinoline. 分子名称: 6-{(1S)-1-[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]ethyl}quinoline, HEPATOCYTE GROWTH FACTOR RECEPTOR 著者 McTigue, M, Grodsky, N, Ryan, K. 登録日 2012-11-15 公開日 2013-11-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Lessons from (S)-6-(1-(6-(1-Methyl-1H-Pyrazol-4-Yl)-[1,2, 4]Triazolo[4,3-B]Pyridazin-3-Yl)Ethyl)Quinoline (Pf-04254644), an Inhibitor of Receptor Tyrosine Kinase C-met with High Protein Kinase Selectivity But Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats. J.Med.Chem., 56, 2013
3ZCL	X-ray Structure of c-Met kinase in complex with inhibitor (S)-3-(1-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-N-isopropyl-(1,2,4)triazolo(4,3- b)pyridazin-6-amine 分子名称: (S)-3-(1-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-N-isopropyl-(1,2,4)triazolo(4,3-b)pyridazin-6-amine, HEPATOCYTE GROWTH FACTOR RECEPTOR 著者 McTigue, M, Grodsky, N, Ryan, K. 登録日 2012-11-20 公開日 2013-11-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Lessons from (S)-6-(1-(6-(1-Methyl-1H-Pyrazol-4-Yl)-[1,2, 4]Triazolo[4,3-B]Pyridazin-3-Yl)Ethyl)Quinoline (Pf-04254644), an Inhibitor of Receptor Tyrosine Kinase C-met with High Protein Kinase Selectivity But Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats. J.Med.Chem., 56, 2013
3ZQQ	Crystal structure of the full-length small terminase from a SPP1-like bacteriophage 分子名称: TERMINASE SMALL SUBUNIT 著者 Buttner, C.R, Chechik, M, Ortiz-Lombardia, M, Smits, C, Chechik, V, Jeschke, G, Dykeman, E, Benini, S, Alonso, J.C, Antson, A.A. 登録日 2011-06-10 公開日 2011-12-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural Basis for DNA Recognition and Loading Into a Viral Packaging Motor. Proc.Natl.Acad.Sci.USA, 109, 2012
3PTE	THE REFINED CRYSTALLOGRAPHIC STRUCTURE OF A DD-PEPTIDASE PENICILLIN-TARGET ENZYME AT 1.6 A RESOLUTION 分子名称: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRANSPEPTIDASE 著者 Kelly, J.A, Kuzin, A.P. 登録日 1994-08-05 公開日 1995-08-15 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The refined crystallographic structure of a DD-peptidase penicillin-target enzyme at 1.6 A resolution. J.Mol.Biol., 254, 1995
3PW4	Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1, CALCIUM ION, ... 著者 Banerjee, S. 登録日 2010-12-07 公開日 2011-08-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
3PTD	PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D274S 分子名称: PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C 著者 Heinz, D.W. 登録日 1997-07-17 公開日 1998-01-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis. Biochemistry, 36, 1997
3PRC	PHOTOSYNTHETIC REACTION CENTER FROM RHODOPSEUDOMONAS VIRIDIS (QB-DEPLETED) 分子名称: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ... 著者 Lancaster, C.R.D, Michel, H. 登録日 1997-07-29 公開日 1998-11-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The coupling of light-induced electron transfer and proton uptake as derived from crystal structures of reaction centres from Rhodopseudomonas viridis modified at the binding site of the secondary quinone, QB. Structure, 5, 1997
3ZQC	Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal beta-hairpin conformation 分子名称: MRE-1, MYB3 著者 Wei, S.-Y, Lou, Y.-C, Tsai, J.-Y, Hsu, H.-M, Tai, J.-H, Hsiao, C.-D, Chen, C. 登録日 2011-06-09 公開日 2012-04-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the Trichomonas Vaginalis Myb3 DNA-Binding Domain Bound to a Promoter Sequence Reveals a Unique C-Terminal Beta-Hairpin Conformation. Nucleic Acids Res., 40, 2012
3Q8W	A b-aminoacyl containing thiazolidine derivative and DPPIV complex 分子名称: Dipeptidyl peptidase 4, N-(4-{[({(2R)-3-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,3-thiazolidin-2-yl}carbonyl)amino]methyl}phenyl)-D-valine 著者 Lee, J.O, Song, D.H. 登録日 2011-01-07 公開日 2011-03-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.64 Å) 主引用文献 Discovery of b-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors To be Published
3QCF	Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization 分子名称: 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION 著者 Sheriff, S. 登録日 2011-01-16 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop J.Med.Chem., 54, 2011
3FGM	Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2008-12-06 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393, 2009
3F4K	Crystal structure of a probable methyltransferase from Bacteroides thetaiotaomicron. Northeast Structural Genomics target BtR309. 分子名称: Putative methyltransferase 著者 Seetharaman, J, Lew, S, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2008-10-31 公開日 2008-11-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a probable methyltransferase from Bacteroides thetaiotaomicron. Northeast Structural Genomics target BtR309. To be Published
3QHM	Crystal analysis of the complex structure, E342A-cellotetraose, of endocellulase from pyrococcus horikoshii 分子名称: 458aa long hypothetical endo-1,4-beta-glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Kim, H.-W, Ishikawa, K. 登録日 2011-01-26 公開日 2012-02-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Functional analysis of hyperthermophilic endocellulase from Pyrococcus horikoshii by crystallographic snapshots Biochem.J., 437, 2011
3QCG	Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid 分子名称: 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, ACETIC ACID, Receptor-type tyrosine-protein phosphatase gamma 著者 Sheriff, S. 登録日 2011-01-16 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop J.Med.Chem., 54, 2011
409D	CRYSTAL STRUCTURE OF AN RNA R(CCCIUGGG) WITH THREE INDEPENDENT DUPLEXES INCORPORATING TANDEM I.U WOBBLES 分子名称: RNA (5'-R(*CP*CP*CP*IP*UP*GP*GP*G)-3') 著者 Pan, B, Mitra, S.N, Sun, L, Hart, D, Sundaralingam, M. 登録日 1998-06-26 公開日 1999-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of an RNA octamer duplex r(CCCIUGGG)2 incorporating tandem I.U wobbles. Nucleic Acids Res., 26, 1998
3OBQ	Crystal Structure of the Tsg101 UEV domain in complex with a human HRS PSAP peptide 分子名称: Hepatocyte growth factor-regulated tyrosine kinase substrate, Tumor susceptibility gene 101 protein 著者 Im, Y.J, Hurley, J.H. 登録日 2010-08-09 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction. Structure, 18, 2010
418D	5'-R(*GP*UP*GP*CP*AP*CP*A)-D(P*C)-3' 分子名称: RNA (5'-R(*GP*UP*GP*CP*AP*CP*AP*C)-3') 著者 Mitra, S.N, Biswas, R, Shi, K, Sundaralingam, M. 登録日 1998-08-12 公開日 2003-06-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of an RNA duplex [r(gugcaca)dC]2 with 3'-dinucleoside overhangs forming a superhelix. J.Biomol.Struct.Dyn., 11, 2000
43CA	CRYSTALLOGRAPHIC STRUCTURE OF THE ESTEROLYTIC AND AMIDOLYTIC 43C9 ANTIBODY WITH BOUND P-NITROPHENOL 分子名称: P-NITROPHENOL, PROTEIN (IMMUNOGLOBULIN (HEAVY CHAIN)), PROTEIN (IMMUNOGLOBULIN (LIGHT CHAIN)) 著者 Thayer, M.M, Getzoff, E.D, Roberts, V.A. 登録日 1999-03-10 公開日 1999-08-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for amide hydrolysis catalyzed by the 43C9 antibody. J.Mol.Biol., 291, 1999
3OBX	Crystal structure of the Tsg101 UEV domain in complex with a HIV-1 Gag P7A mutant peptide 分子名称: Gag polyprotein, Tumor susceptibility gene 101 protein 著者 Im, Y.J, Hurley, J.H. 登録日 2010-08-09 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction. Structure, 18, 2010

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