2WG6
| Proteasome-Activating Nucleotidase (PAN) N-domain (57-134) from Archaeoglobus fulgidus fused to GCN4, P61A Mutant | 分子名称: | GENERAL CONTROL PROTEIN GCN4, PROTEASOME-ACTIVATING NUCLEOTIDASE | 著者 | Hartmann, M.D, Djuranovic, S, Ursinus, A, Zeth, K, Lupas, A.N. | 登録日 | 2009-04-15 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Activity of the N-Terminal Substrate Recognition Domains in Proteasomal Atpases. Mol.Cell, 34, 2009
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4FYJ
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4Y8S
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5UH5
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-10 | 公開日 | 2017-04-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.746 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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5UHD
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA in complex with Rifampin | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.01 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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5UHC
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.796 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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4YBB
| High-resolution structure of the Escherichia coli ribosome | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D. | 登録日 | 2015-02-18 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | High-resolution structure of the Escherichia coli ribosome. Nat.Struct.Mol.Biol., 22, 2015
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4Y8I
| Yeast 20S proteasome in complex with Ac-PLL-ep | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PLL-ep, CHLORIDE ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2015-02-16 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
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5AFJ
| alpha7-AChBP in complex with lobeline and fragment 1 | 分子名称: | (3S)-6-(4-bromophenyl)-3-hydroxy-1,3-dimethyl-2,3-dihydropyridin-4(1H)-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE-BINDING PROTEIN, ... | 著者 | Spurny, R, Debaveye, S, Farinha, A, Veys, K, Gossas, T, Atack, J, Bertrand, D, Kemp, J, Vos, A, Danielson, U.H, Tresadern, G, Ulens, C. | 登録日 | 2015-01-22 | 公開日 | 2015-05-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular Blueprint of Allosteric Binding Sites in a Homologue of the Agonist-Binding Domain of the Alpha7 Nicotinic Acetylcholine Receptor. Proc.Natl.Acad.Sci.USA, 112, 2015
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4Y8R
| Yeast 20S proteasome beta2-H116D mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2015-02-16 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
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4YA9
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4G4S
| Structure of Proteasome-Pba1-Pba2 Complex | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, Proteasome assembly chaperone 2, ... | 著者 | Kish-Trier, E, Robinson, H, Stadtmueller, B.M, Hill, C.P. | 登録日 | 2012-07-16 | 公開日 | 2012-09-05 | 最終更新日 | 2013-04-10 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structure of a Proteasome Pba1-Pba2 Complex: IMPLICATIONS FOR PROTEASOME ASSEMBLY, ACTIVATION, AND BIOLOGICAL FUNCTION. J.Biol.Chem., 287, 2012
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3BX3
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5AHJ
| Yeast 20S proteasome in complex with Macyranone A | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 20S PROTEASOME, CHLORIDE ION, ... | 著者 | Etzbach, L, Plaza, A, Dubiella, C, Groll, M, Kaiser, M, Mueller, R. | 登録日 | 2015-02-06 | 公開日 | 2015-02-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome. J.Am.Chem.Soc., 137, 2015
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4IK9
| High resolution structure of GCaMP3 dimer form 2 at pH 7.5 | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, RCaMP, ... | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | 登録日 | 2012-12-25 | 公開日 | 2014-01-29 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement. Protein Cell, 4, 2013
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5AJ0
| Cryo electron microscopy of actively translating human polysomes (POST state). | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. | 登録日 | 2015-02-19 | 公開日 | 2015-05-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
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5D9Y
| Crystal structure of TET2-5fC complex | 分子名称: | DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ... | 著者 | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | 登録日 | 2015-08-19 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.971 Å) | 主引用文献 | Structural insight into substrate preference for TET-mediated oxidation. Nature, 527, 2015
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4IK8
| High resolution structure of GCaMP3 dimer form 1 at pH 7.5 | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | 登録日 | 2012-12-25 | 公開日 | 2014-02-05 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement. Protein Cell, 4, 2013
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4IQB
| High Resolution Crystal Structure of C.elegans Thymidylate Synthase | 分子名称: | SULFATE ION, Thymidylate synthase | 著者 | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | 登録日 | 2013-01-11 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
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4Y6A
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3BSA
| Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor | 分子名称: | 2-({3-[5-hydroxy-2-(3-methylbutyl)-3-oxo-6-(1,3-thiazol-5-yl)-2,3-dihydropyridazin-4-yl]-1,1-dioxido-2H-1,2,4-benzothia diazin-7-yl}oxy)acetamide, RNA-directed RNA polymerase | 著者 | Han, Q, Showalter, R.E, Zhao, Q, Kissinger, C.R. | 登録日 | 2007-12-23 | 公開日 | 2008-12-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg.Med.Chem.Lett., 18, 2008
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4Y80
| Yeast 20S proteasome in complex with Ac-LAI-ep | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAI-ep, CHLORIDE ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2015-02-16 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
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5DEI
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3CD6
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3BVN
| High resolution crystal structure of HLA-B*1402 in complex with the latent membrane protein 2 peptide (LMP2) of Epstein-Barr virus | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B*1402 alpha chain, ... | 著者 | Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A. | 登録日 | 2008-01-07 | 公開日 | 2009-02-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens J.Biol.Chem., 284, 2009
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