5VVD
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![BU of 5vvd by Molmil](/molmil-images/mine/5vvd) | Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)benzonitrile | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-{[(2-amino-4-methylquinolin-7-yl)methyl]amino}ethyl)benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2017-05-19 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem., 60, 2017
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5EKE
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![BU of 5eke by Molmil](/molmil-images/mine/5eke) | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (F215A mutant) | 分子名称: | MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501 | 著者 | Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2015-11-03 | 公開日 | 2016-01-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun, 7, 2016
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5EPL
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![BU of 5epl by Molmil](/molmil-images/mine/5epl) | Crystal Structure of chromodomain of CBX4 in complex with inhibitor UNC3866 | 分子名称: | E3 SUMO-protein ligase CBX4, UNKNOWN ATOM OR ION, unc3866 | 著者 | Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-11-11 | 公開日 | 2015-12-23 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat.Chem.Biol., 12, 2016
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5EKP
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![BU of 5ekp by Molmil](/molmil-images/mine/5ekp) | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (WT) | 分子名称: | MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501 | 著者 | Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2015-11-03 | 公開日 | 2016-01-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.194 Å) | 主引用文献 | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun, 7, 2016
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6NZM
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![BU of 6nzm by Molmil](/molmil-images/mine/6nzm) | Brutons tyrosine kinase in complex with compound 50. | 分子名称: | 1,2-ETHANEDIOL, N-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-N'-{3-[(2R)-1-(2-hydroxyethyl)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea, Tyrosine-protein kinase BTK | 著者 | Marcotte, D.J. | 登録日 | 2019-02-14 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Optimization of novel reversible Bruton's tyrosine kinase inhibitors identified using Tethering-fragment-based screens. Bioorg.Med.Chem., 27, 2019
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5ESP
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5K6U
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![BU of 5k6u by Molmil](/molmil-images/mine/5k6u) | Sidekick-1 immunoglobulin domains 1-4, crystal form 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CESIUM ION, IODIDE ION, ... | 著者 | Jin, X, Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. | 登録日 | 2016-05-25 | 公開日 | 2016-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
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2W72
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![BU of 2w72 by Molmil](/molmil-images/mine/2w72) | DEOXYGENATED STRUCTURE OF A DISTAL SITE HEMOGLOBIN MUTANT PLUS XE | 分子名称: | HUMAN HEMOGLOBIN A, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Miele, A.E, Draghi, F, Sciara, G, Johnson, K.A, Renzi, F, Vallone, B, Brunori, M, Savino, C. | 登録日 | 2008-12-19 | 公開日 | 2009-04-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Pattern of Cavities in Globins: The Case of Human Hemoglobin. Biopolymers, 91, 2009
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5KM8
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5KSS
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![BU of 5kss by Molmil](/molmil-images/mine/5kss) | Stationary phase survival protein E (SurE) from Xylella fastidiosa - XFSurE-Ds (Dimer Smaller) | 分子名称: | 5'-nucleotidase SurE, CHLORIDE ION, IODIDE ION, ... | 著者 | Machado, A.T.P, Fonseca, E.M.B, Dos Reis, M.A, Saraiva, A.M, Dos Santos, C.A, De Toledo, A.M.S, Polikarpov, I, De Souza, A.P, Aparicio, R, Iulek, J. | 登録日 | 2016-07-09 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X-ray scattering studies, and normal mode analysis. Proteins, 85, 2017
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1ZEV
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5KUP
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![BU of 5kup by Molmil](/molmil-images/mine/5kup) | Bruton's tyrosine kinase (BTK) with pyridazinone compound 9 | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-6-oxidanylidene-5-(pyrimidin-4-ylamino)pyridin-3-yl]pyridin-2-yl]phthalazin-1-one, GLYCEROL, ... | 著者 | Eigenbrot, C, Yu, C. | 登録日 | 2016-07-13 | 公開日 | 2016-09-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.389 Å) | 主引用文献 | Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations. Acs Chem.Biol., 11, 2016
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1D3F
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1D3M
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![BU of 1d3m by Molmil](/molmil-images/mine/1d3m) | METHIONINE CORE MUTATION | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | 著者 | Gassner, N.C, Matthews, B.W. | 登録日 | 1999-09-29 | 公開日 | 1999-09-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Use of differentially substituted selenomethionine proteins in X-ray structure determination. Acta Crystallogr.,Sect.D, 55, 1999
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7KMI
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![BU of 7kmi by Molmil](/molmil-images/mine/7kmi) | LY-CoV481 neutralizing antibody against SARS-CoV-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV481 Fab heavy chain, ... | 著者 | Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. | 登録日 | 2020-11-02 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
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6EGY
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![BU of 6egy by Molmil](/molmil-images/mine/6egy) | Crystal structure of cytochrome c in complex with mono-PEGylated sulfonatocalix[4]arene | 分子名称: | Cytochrome c iso-1, HEME C, SULFATE ION, ... | 著者 | Mummidivarapu, V.V.S, Rennie, M.L, Crowley, P.B. | 登録日 | 2017-09-12 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Noncovalent PEGylation via Sulfonatocalix[4]arene-A Crystallographic Proof. Bioconjug.Chem., 29, 2018
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1D8W
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![BU of 1d8w by Molmil](/molmil-images/mine/1d8w) | L-RHAMNOSE ISOMERASE | 分子名称: | L-RHAMNOSE ISOMERASE, ZINC ION | 著者 | Korndorfer, I.P, Matthews, B.W. | 登録日 | 1999-10-26 | 公開日 | 2000-09-27 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution. J.Mol.Biol., 300, 2000
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6N3Y
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1PX3
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![BU of 1px3 by Molmil](/molmil-images/mine/1px3) | E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) | 分子名称: | DIMETHYL SULFOXIDE, MAGNESIUM ION, SODIUM ION, ... | 著者 | Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E. | 登録日 | 2003-07-02 | 公開日 | 2004-06-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase Biochemistry, 42, 2003
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6MIL
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![BU of 6mil by Molmil](/molmil-images/mine/6mil) | Crystal structure of AF9 YEATS domain in complex with histone H3K9bu | 分子名称: | DI(HYDROXYETHYL)ETHER, Histone H3K9bu, MALONATE ION, ... | 著者 | Vann, K.R, Klein, B.J, Kutateladze, T.G. | 登録日 | 2018-09-19 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
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6D0N
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![BU of 6d0n by Molmil](/molmil-images/mine/6d0n) | Crystal structure of a CLC-type fluoride/proton antiporter, V319G mutant | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | 登録日 | 2018-04-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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1CE8
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![BU of 1ce8 by Molmil](/molmil-images/mine/1ce8) | CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, INOSINIC ACID, ... | 著者 | Thoden, J.B, Raushel, F.M, Holden, H.M. | 登録日 | 1999-03-18 | 公開日 | 1999-07-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The binding of inosine monophosphate to Escherichia coli carbamoyl phosphate synthetase. J.Biol.Chem., 274, 1999
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6NWQ
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![BU of 6nwq by Molmil](/molmil-images/mine/6nwq) | Chronic traumatic encephalopathy Type II Tau filament | 分子名称: | Microtubule-associated protein tau | 著者 | Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W. | 登録日 | 2019-02-07 | 公開日 | 2019-03-27 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature, 568, 2019
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2X4T
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![BU of 2x4t by Molmil](/molmil-images/mine/2x4t) | Crystal structure of MHC CLass I HLA-A2.1 bound to a Peiodate- cleavable peptide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 65 KDA PHOSPHOPROTEIN, BETA-2-MICROGLOBULIN, ... | 著者 | Rodenko, B, Toebes, M, Celie, P.H.N, Perrakis, A, Schumacher, T.N.M, Ovaa, H. | 登録日 | 2010-02-02 | 公開日 | 2010-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger. J.Am.Chem.Soc., 131, 2009
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5WEG
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![BU of 5weg by Molmil](/molmil-images/mine/5weg) | Crystal Structure of UDP-glucose pyrophosphorylase from Sugarcane | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, UTP--glucose-1-phosphate uridylyltransferase | 著者 | Cotrim, C.A, Soares, J.S.M, Kobe, B, Menossi, M. | 登録日 | 2017-07-10 | 公開日 | 2018-03-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure and insights into the oligomeric state of UDP-glucose pyrophosphorylase from sugarcane. PLoS ONE, 13, 2018
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