2W72

DEOXYGENATED STRUCTURE OF A DISTAL SITE HEMOGLOBIN MUTANT PLUS XE

Summary for 2W72

Related1XZV 1FN3 1Y4P 1LFL 1HBA 1Y4F 1LFZ 1O1L 2HBF 1O1N 1CBM 1BAB 1A3O 1DKE 1DXT 1A9W 2HHD 1J7Y 1J3Y 1BIJ 2DN2 1HGB 2HBD 1AJ9 1XXT 1HBS 1ABY 1ABW 1LFT 1YEV 1JY7 1R1Y 1YHR 1YEQ 1RVW 1HAB 1GBV 1YEN 1J40 1HCO 1NEJ 1Y45 1GLI 1CLS 1Y0D 1YG5 1YE1 2DN3 1BZ0 2HBC 1SDL 1Y85 1A01 1GZX 1C7C 1QI8 1RPS 1YIE 1XY0 1LFV 1A0Z 1O1I 1IRD 2D60 1Y46 1XZ4 1HAC 1XZ7 1DXU 1J7S 1O1K 1Y2Z 1KD2 1XZ2 1HGC 2HBS 1MKO 1RQ4 1A3N 1HBB 1BUW 1Y01 2HCO 1CBL 1YFF 1HHO 1XZ5 1Y7G 1YH9 1YE2 1YZI 1B86 1YHE 1Y7C 1QSH 1Y4Q 1CH4 1YGF 1Y09 1C7B 1Y5J 2D5Z 2HHE 1QXE 1VWT 1COH 1J41 1Y4G 1Y35 1O1O 2W6V 2W6W 2W6X 2W6Y 1Y0T 1SHR 1O1P 1M9P 1RQA 1XZU 1UIW 1YGD 1YVQ 1LFY 1HGA 1LFQ 1Y83 1Y22 1BBB 1Y4B 1GBU 1K0Y 1Y7Z 1LJW 1YEO 1Y31 1QXD 1Y0A 1BZ1 1Y0C 1YIH 1Z8U 1SDK 1A00 1Y7D 2DN1 1NQP 1K1K 6HBW 1XYE 1YE0 1NIH 4HHB 1Y4V 1C7D 1Y8W 1Y0W 1A0U 1G9V 1BZZ 1HDB 1FDH 1YDZ 1THB 1CMY 1Y5F 1YEU 1R1X 1QSI 1SI4 1Y4R 1J7W 2HBE 1O1M 1YVT 1J3Z 1Y5K 1RQ3 1DXV 1O1J
DescriptorHUMAN HEMOGLOBIN A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (9 entities in total)
Functional Keywordsiron, heme, glycation, transport, acetylation, phosphoprotein, packing defects, disease mutation, distal site point mutation, oxygen transport, hydrophobic cavities, polymorphism, glycoprotein, metal-binding
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight67753.41
Authors
Miele, A.E.,Draghi, F.,Sciara, G.,Johnson, K.A.,Renzi, F.,Vallone, B.,Brunori, M.,Savino, C. (deposition date: 2008-12-19, release date: 2009-04-28, Last modification date: 2011-08-17)
Primary citation
Savino, C.,Miele, A.E.,Draghi, F.,Johnson, K.A.,Sciara, G.,Brunori, M.,Vallone, B.
Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Biopolymers, 91:1097-, 2009
PubMed: 19365817 (PDB entries with the same primary citation)
DOI: 10.1002/BIP.21201
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.07 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1942301.9%61.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2w72
no rotation
Molmil generated image of 2w72
rotated about x axis by 90°
Molmil generated image of 2w72
rotated about y axis by 90°