6N3Y

Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Guanosine

Summary for 6N3Y

• Entry DOI: 10.2210/pdb6n3y/pdb
• Descriptor: Histidine triad nucleotide-binding protein 1, 5'-O-{[2-(1H-indol-3-yl)ethyl]carbamoyl}guanosine, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: hint, histidine triad, hit, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 28732.73

Authors

Strom, A.M.,Finzel, B.C. (deposition date: 2018-11-16, release date: 2019-09-18, Last modification date: 2023-10-11)

• Primary citation: Shah, R.M.,Peterson, C.,Strom, A.,Dillenburg, M.,Finzel, B.,Kitto, K.F.,Fairbanks, C.,Wilcox, G.,Wagner, C.R.; Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice.; Acs Chem Neurosci, 10:4385-4393, 2019; PubMed: 31503445; DOI: 10.1021/acschemneuro.9b00432

Experimental method

X-RAY DIFFRACTION (1.8 Å)