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6N3Y

Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Guanosine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histidine triad nucleotide-binding protein 1polymer12914096.22UniProt (P49773)
Pfam (PF01230)
Homo sapiens (Human)Adenosine 5'-monophosphoramidase,Protein kinase C inhibitor 1,Protein kinase C-interacting protein 1,PKCI-1
2C
(A)
5'-O-{[2-(1H-indol-3-yl)ethyl]carbamoyl}guanosinenon-polymer469.51Chemie (HHJ)
3D, E
(B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4F, G
(A, B)
waterwater18.055Chemie (HOH)
Sequence modifications
A, B: 1 - 126 (UniProt: P49773)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28192.4
Non-Polymers*Number of molecules3
Total formula weight540.4
All*Total formula weight28732.7
*Water molecules are not included.

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PDB entries from 2025-07-02

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