5EPL

Crystal Structure of chromodomain of CBX4 in complex with inhibitor UNC3866

Summary for 5EPL

Entry DOI	10.2210/pdb5epl/pdb
Related	5EPJ 5EPK 5EQ0
Related PRD ID	PRD_002208
Descriptor	E3 SUMO-protein ligase CBX4, unc3866, UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywords	structural genomics, structural genomics consortium, sgc, transcription-transcription inhibitor complex, transcription/transcription inhibitor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	16298.69
Authors	Liu, Y.,Tempel, W.,Walker, J.R.,Stuckey, J.I.,Dickson, B.M.,James, L.I.,Frye, S.V.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2015-11-11, release date: 2015-12-23, Last modification date: 2019-11-27)
Primary citation	Stuckey, J.I.,Dickson, B.M.,Cheng, N.,Liu, Y.,Norris, J.L.,Cholensky, S.H.,Tempel, W.,Qin, S.,Huber, K.G.,Sagum, C.,Black, K.,Li, F.,Huang, X.P.,Roth, B.L.,Baughman, B.M.,Senisterra, G.,Pattenden, S.G.,Vedadi, M.,Brown, P.J.,Bedford, M.T.,Min, J.,Arrowsmith, C.H.,James, L.I.,Frye, S.V. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat.Chem.Biol., 12:180-187, 2016 Cited by PubMed: 26807715 DOI: 10.1038/nchembio.2007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation