1C2X
 
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7U0R
 | | Crystal structure of Methanomethylophilus alvus PylRS(N166A/V168A) complexed with meta-trifluoromethyl-2-benzylmalonate and AMP-PNP | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Swenson, C.V, Roe, L.T, Fricke, R.C.B, Smaga, S.S, Gee, C.L, Schepartz, A. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-alpha-amino acids in vitro and in vivo.
Nat.Chem., 15, 2023
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4XFO
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7D79
 | | The structure of DcsB complex with its substrate analogue | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DltD domain-containing protein, ... | | 著者 | Tang, Y, Zhou, J.H, Wang, G.Q. | | 登録日 | 2020-10-03 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.10411429 Å) | | 主引用文献 | A Polyketide Cyclase That Forms Medium-Ring Lactones.
J.Am.Chem.Soc., 143, 2021
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2XVU
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4XCK
 | | Vibrio cholerae O395 Ribokinase complexed with ADP, Ribose and Cesium ion. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CESIUM ION, Ribokinase, ... | | 著者 | Paul, R, Patra, M.D, Sen, U. | | 登録日 | 2014-12-18 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Crystal Structure of Apo and Ligand Bound Vibrio cholerae Ribokinase (Vc-RK): Role of Monovalent Cation Induced Activation and Structural Flexibility in Sugar Phosphorylation.
Adv. Exp. Med. Biol., 842, 2015
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7TDF
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7TBG
 | | AtTPC1 D454N with 1 mM Ca2+ | | 分子名称: | CALCIUM ION, SODIUM ION, Two pore calcium channel protein 1 | | 著者 | Dickinson, M.S, Stroud, R.M. | | 登録日 | 2021-12-22 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Molecular basis of multistep voltage activation in plant two-pore channel 1.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4XFN
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7DQK
 | | A nicotine MATE transporter, Nicotiana tabacum MATE2 (NtMATE2) | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Tanaka, Y, Tsukazaki, T, Sasaki, A, Iwaki, S. | | 登録日 | 2020-12-24 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structures of a nicotine MATE transporter provide insight into its mechanism of substrate transport.
Febs Lett., 595, 2021
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7X4B
 | | Crystal Structure of An Anti-CRISPR Protein | | 分子名称: | Anti-CRISPR protein (AcrIIC1), SULFATE ION | | 著者 | Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J. | | 登録日 | 2022-03-02 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1.
Nat Commun, 13, 2022
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7PFO
 | | Core human replisome | | 分子名称: | Cell division control protein 45 homolog, Claspin, DNA polymerase epsilon catalytic subunit A, ... | | 著者 | Jones, M.J, Yeeles, J.T.P. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of a human replisome shows the organisation and interactions of a DNA replication machine.
Embo J., 40, 2021
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7DDE
 | | Cryo-EM structure of the Ape4 and Nbr1 complex | | 分子名称: | Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | | 著者 | Zhang, J, Ye, K. | | 登録日 | 2020-10-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
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7DD9
 | | Cryo-EM structure of the Ams1 and Nbr1 complex | | 分子名称: | Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | | 著者 | Zhang, J, Ye, K. | | 登録日 | 2020-10-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
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7XQ5
 | | Crystal structure of ScIno2p-ScIno4p bound promoter DNA | | 分子名称: | DNA (5'-D(*GP*AP*TP*TP*TP*TP*CP*AP*CP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*GP*TP*GP*AP*AP*AP*AP*T)-3'), HEXANE-1,6-DIOL, ... | | 著者 | Khan, M.H, Lu, X. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Analysis of Ino2p/Ino4p Mutual Interactions and Their Binding Interface with Promoter DNA.
Int J Mol Sci, 23, 2022
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7UG9
 | | Crystal structure of RNase AM PHP domain | | 分子名称: | 5'-3' exoribonuclease, MANGANESE (II) ION, SULFATE ION | | 著者 | Doamekpor, S.K, Tong, L. | | 登録日 | 2022-03-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Identification of a novel deFADding activity in human, yeast and bacterial 5' to 3' exoribonucleases.
Nucleic Acids Res., 50, 2022
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7UOF
 | | Dihydroorotase from M. jannaschii | | 分子名称: | Dihydroorotase, ZINC ION | | 著者 | Vitali, J, Nix, J.C, Newman, H.E, Colaneri, M.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of Methanococcus jannaschii dihydroorotase.
Proteins, 91, 2023
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2XVV
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7UMV
 | | Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((5,6-dihydropyrido[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | | 分子名称: | 1-{[(10aP)-5,6-dihydropyrido[2,3-h]quinazolin-2-yl]sulfanyl}-3,3-dimethylbutan-2-one, ACETATE ION, Dual specificity protein phosphatase 10 | | 著者 | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | | 登録日 | 2022-04-07 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
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7UN0
 | | Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-chloro-5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | | 分子名称: | 1-[(9-chlorobenzo[h]quinazolin-2-yl)sulfanyl]-3,3-dimethylbutan-2-one, Dual specificity protein phosphatase 10 | | 著者 | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | | 登録日 | 2022-04-08 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
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7UN4
 | | Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | | 分子名称: | 1-{[(9aM)-5,6-dihydrothieno[2,3-h]quinazolin-2-yl]sulfanyl}-3,3-dimethylbutan-2-one, Dual specificity protein phosphatase 10 | | 著者 | Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M. | | 登録日 | 2022-04-08 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
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7B1D
 | | Cryo-EM of Aedes Aegypti Toll5A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor | | 著者 | Gangloff, M, Hardwick, S.W, Chirgadze, D.Y. | | 登録日 | 2020-11-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.
Nat Commun, 13, 2022
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7B1C
 | | Cryo-EM of Aedes Aegypti Toll5A trimer bound to Spz1C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AAEL013433-PA, ... | | 著者 | Gangloff, M, Hardwick, S.W, Chirgadze, D.Y. | | 登録日 | 2020-11-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.
Nat Commun, 13, 2022
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7B1B
 | | Cryo-EM of Aedes Aegypti Toll5A dimer bound to Spz1C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AAEL013433-PA, ... | | 著者 | Gangloff, M, Hardwick, S.W, Chirgadze, D.Y. | | 登録日 | 2020-11-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | | 主引用文献 | Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.
Nat Commun, 13, 2022
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7V9E
 | | Crystal structure of a methyl transferase ribozyme | | 分子名称: | BARIUM ION, GUANINE, RNA (68-MER), ... | | 著者 | Deng, J, Lilley, D.M.J, Huang, L. | | 登録日 | 2021-08-25 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and mechanism of a methyltransferase ribozyme.
Nat.Chem.Biol., 18, 2022
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