7B1C

Cryo-EM of Aedes Aegypti Toll5A trimer bound to Spz1C

Summary for 7B1C

• Entry DOI: 10.2210/pdb7b1c/pdb
• EMDB information: 11982 11983 11984
• Descriptor: Toll-like receptor, AAEL013433-PA, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: mosquito vector biology, toll receptor, lrr, cystine knot domain, immune system
• Biological source: Aedes aegypti (yellow fever mosquito); More
• Total number of polymer chains: 5
• Total formula weight: 296177.19

Authors

Gangloff, M.,Hardwick, S.W.,Chirgadze, D.Y. (deposition date: 2020-11-24, release date: 2022-07-13, Last modification date: 2023-01-25)

• Primary citation: Saucereau, Y.,Wilson, T.H.,Tang, M.C.K.,Moncrieffe, M.C.,Hardwick, S.W.,Chirgadze, D.Y.,Soares, S.G.,Marcaida, M.J.,Gay, N.J.,Gangloff, M.; Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.; Nat Commun, 13:5110-5110, 2022; PubMed: 36042238; DOI: 10.1038/s41467-022-32690-6

Experimental method

ELECTRON MICROSCOPY (3.74 Å)