3SYZ
 
 | | Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dNaM as templating nucleobase | | 分子名称: | (5'-D(*AP*AP*AP*(BMN)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA polymerase I, ... | | 著者 | Betz, K, Diederichs, K, Marx, A. | | 登録日 | 2011-07-18 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
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4FXJ
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4KE8
 | | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with monopalmitoyl glycerol analogue | | 分子名称: | Thermostable monoacylglycerol lipase, tetradecyl hydrogen (R)-(3-azidopropyl)phosphonate | | 著者 | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | | 登録日 | 2013-04-25 | | 公開日 | 2013-09-18 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase.
J.Biol.Chem., 288, 2013
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3SZ2
 | | Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dG as templating nucleobase | | 分子名称: | (5'-D(*AP*AP*AP*GP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3'), DNA polymerase I, ... | | 著者 | Betz, K, Marx, A, Diederichs, K. | | 登録日 | 2011-07-18 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
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4KEA
 | | Crystal structure of D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in space group P212121 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase | | 著者 | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | | 登録日 | 2013-04-25 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase.
J.Biol.Chem., 288, 2013
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4K82
 | | Crystal structure of lv-ranaspumin (Lv-RSN-1) from the foam nest of Leptodactylus vastus, monoclinic crystal form | | 分子名称: | Lv-ranaspumin (Lv-RSN-1) | | 著者 | Hissa, D.C, Bezerra, G.A, Melo, V.M.M, Gruber, K. | | 登録日 | 2013-04-17 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Unique Crystal Structure of a Novel Surfactant Protein from the Foam Nest of the Frog Leptodactylus vastus.
Chembiochem, 15, 2014
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3SV4
 | | Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dT as templating nucleobase | | 分子名称: | (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA polymerase I, ... | | 著者 | Betz, K, Diederichs, K, Marx, A. | | 登録日 | 2011-07-12 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
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4FQ1
 | | Crystal Structure of PGT121 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2012-06-24 | | 公開日 | 2012-11-14 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3R1R
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4PBG
 | | 6-PHOSPHO-BETA-GALACTOSIDASE FORM-CST | | 分子名称: | 6-O-phosphono-beta-D-galactopyranose, 6-PHOSPHO-BETA-D-GALACTOSIDASE | | 著者 | Wiesmann, C, Schulz, G.E. | | 登録日 | 1997-02-21 | | 公開日 | 1997-07-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures and mechanism of 6-phospho-beta-galactosidase from Lactococcus lactis.
J.Mol.Biol., 269, 1997
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4FQC
 | | Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan | | 分子名称: | Fab heavy chain, Fab light chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2012-06-25 | | 公開日 | 2012-11-14 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FQQ
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4N7E
 | | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with AF38469 | | 分子名称: | 2-[(6-methylpyridin-2-yl)carbamoyl]-5-(trifluoromethyl)benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, ... | | 著者 | Andersen, J.L, Strandbygaard, D, Thirup, S. | | 登録日 | 2013-10-15 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin.
Bioorg.Med.Chem.Lett., 24, 2014
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3UXF
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4QC3
 | | Crystal structure of human BAZ2B bromodomain in complex with a diacetylated histone 4 peptide (H4K8acK12ac) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B, diacetylated histone 4 peptide (H4K8acK12ac) | | 著者 | Tallant, C, Jose, B, Picaud, S, Chaikuad, A, Filippakopoulos, P, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-05-09 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
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4QC1
 | | Crystal structure of human BAZ2B bromodomain in complex with an acetylated histone 3 peptide (H3K14ac) | | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2B, SULFATE ION, ZINC ION, ... | | 著者 | Tallant, C, Jose, B, Picaud, S, Chaikuad, A, Filippakopoulos, P, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-05-09 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
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4Q6F
 | | Crystal structure of human BAZ2A PHD zinc finger in complex with unmodified H3K4 histone peptide | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2A, ZINC ION, ... | | 著者 | Tallant, C, Overvoorde, L, Krojer, T, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ciulli, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-04-22 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
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4QBM
 | | Crystal structure of human BAZ2A bromodomain in complex with a diacetylated histone 4 peptide (H4K16acK20ac) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2A, histone H4 peptide with sequence Gly-Ala-Lys(ac)-Arg-His-Arg-Lys(ac)-Val-Leu | | 著者 | Tallant, C, Nunez-Alonso, G, Picaud, S, Filippakopoulos, P, Krojer, T, Williams, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-05-08 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
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4JKP
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3UF5
 | | Crystal structure of the mouse Colony-Stimulating Factor 1 (mCSF-1) cytokine | | 分子名称: | CALCIUM ION, Macrophage colony-stimulating factor 1 | | 著者 | Elegheert, J, Bracke, N, Bekaert, A, Savvides, S.N. | | 登録日 | 2011-10-31 | | 公開日 | 2012-08-22 | | 最終更新日 | 2013-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1
Nat.Struct.Mol.Biol., 19, 2012
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3UEZ
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4KE7
 | | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with an 1-myristoyl glycerol analogue | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase, dodecyl hydrogen (S)-(3-azidopropyl)phosphonate | | 著者 | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | | 登録日 | 2013-04-25 | | 公開日 | 2013-09-18 | | 最終更新日 | 2013-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase.
J.Biol.Chem., 288, 2013
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4KTL
 | | Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4,4'-(3-((4-hydroxyphenyl)amino)-1H-pyrazole-4,5-diyl)diphenol | | 分子名称: | 4,4'-{3-[(4-hydroxyphenyl)amino]-1H-pyrazole-4,5-diyl}diphenol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Hudson, S.A. | | 登録日 | 2013-05-20 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121.
Chemmedchem, 8, 2013
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4FQ2
 | | Crystal Structure of 10-1074 Fab | | 分子名称: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2012-06-24 | | 公開日 | 2012-11-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4P0Z
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