3SYZ

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dNaM as templating nucleobase

Summary for 3SYZ

• Entry DOI: 10.2210/pdb3syz/pdb
• Related: 3SV3 3SV4 3SVN 3SVO 3SZ2
• Descriptor: DNA polymerase I, thermostable, (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), (5'-D(*AP*AP*AP*(BMN)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase, artificial base, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 3
• Total formula weight: 70771.32

Authors

Betz, K.,Diederichs, K.,Marx, A. (deposition date: 2011-07-18, release date: 2012-06-06, Last modification date: 2023-09-13)

• Primary citation: Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Dwyer, T.J.,Ordoukhanian, P.,Romesberg, F.E.,Marx, A.; KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.; Nat.Chem.Biol., 8:612-614, 2012; PubMed: 22660438; DOI: 10.1038/nchembio.966

Experimental method

X-RAY DIFFRACTION (1.952 Å)