PDB: 8717 件ウェブページステータス検索Chemie searchBIRD

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4P36	Crystal structure of DJ-1 With Zn(II) bound (crystal 2) 分子名称: 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Protein DJ-1, ZINC ION 著者 Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. 登録日 2014-03-05 公開日 2014-04-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.182 Å) 主引用文献 Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
4P35	Crystal structure of DJ-1 with Zinc(II) bound (crystal I) 分子名称: CHLORIDE ION, GLYCEROL, Protein DJ-1, ... 著者 Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. 登録日 2014-03-05 公開日 2014-04-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
7ICJ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CUCL2 (0.1 MILLIMOLAR) 分子名称: COPPER (II) ION, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*G)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
7TO2	Cryo-EM structure of RIG-I bound to the internal sites of p3SLR30 (+ATP) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2022-01-22 公開日 2022-11-02 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
6FBE	KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the third primer nucleotide. 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*GP*GP*TP*GP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2017-12-19 公開日 2018-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.589 Å) 主引用文献 Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1TQE	Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2 分子名称: Histone deacetylase 9, MEF2 binding site of nur77 promoter, Myocyte-specific enhancer factor 2B 著者 Chen, L, Han, A, He, J, Wu, Y, Liu, J.O. 登録日 2004-06-17 公開日 2004-12-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of Recruitment of Class II Histone Deacetylases by Myocyte Enhancer Factor-2. J.Mol.Biol., 345, 2005
5DDY	Binary complex of human Polymerase lambda with dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, MAGNESIUM ION, ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-08-25 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
5OXJ	Crystal structure of KlenTaq mutant M747K in a closed ternary complex with a O6-MeG:BenziTP base pair 分子名称: ACETATE ION, DNA polymerase I, thermostable, ... 著者 Betz, K, Diederichs, K, Marx, A. 登録日 2017-09-06 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase. Chem. Commun. (Camb.), 53, 2017
2N0Y	NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH 分子名称: Non-structural protein NS-S, RNA polymerase II transcription factor B subunit 1 著者 Cyr, N, de la Fuente, C, Lecoq, L, Guendel, I, Chabot, P.R, Kehn-Hall, K, Omichinski, J.G. 登録日 2015-03-18 公開日 2015-04-22 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A Omega XaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence. Proc.Natl.Acad.Sci.USA, 112, 2015
1O0B	CRYSTAL STRUCTURE OF L-GLUTAMINE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE 分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl tRNA, ... 著者 Bullock, T.L, Perona, J.J. 登録日 2003-02-20 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants J.Mol.Biol., 328, 2003
1O0C	CRYSTAL STRUCTURE OF L-GLUTAMATE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE 分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMIC ACID, Glutaminyl tRNA, ... 著者 Bullock, T.L, Perona, J.J. 登録日 2003-02-20 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants J.Mol.Biol., 328, 2003
7OA4	Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001 分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ... 著者 Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K. 登録日 2021-04-19 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001 To Be Published
3FWC	Sac3:Sus1:Cdc31 complex 分子名称: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1, ... 著者 Stewart, M, Jani, D. 登録日 2009-01-17 公開日 2009-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
3FWB	Sac3:Sus1:Cdc31 complex 分子名称: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1 著者 Stewart, M, Jani, D. 登録日 2009-01-17 公開日 2009-04-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
4N56	Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA 分子名称: 5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3', DNA polymerase I, ... 著者 Wu, E.Y. 登録日 2013-10-09 公開日 2015-01-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
6Q4T	KOD DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), DNA (5'-D(P*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2018-12-06 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl., 58, 2019
2HOJ	Crystal structure of an E. coli thi-box riboswitch bound to thiamine pyrophosphate, manganese ions 分子名称: MAGNESIUM ION, MANGANESE (II) ION, THIAMINE DIPHOSPHATE, ... 著者 Edwards, T.E, Ferre-D'Amare, A.R. 登録日 2006-07-14 公開日 2006-09-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of the Thi-Box Riboswitch Bound to Thiamine Pyrophosphate Analogs Reveal Adaptive RNA-Small Molecule Recognition Structure, 14, 2006
2LBR	Conformation Effects of Base Modification on the Anticodon Stem-loop of Bacillus subtilis tRNATYR 分子名称: RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*UP*AP*(6IA)P*AP*(PSU)P*CP*CP*CP*C)-3') 著者 Denmon, A.P, Wang, J, Nikonowicz, E.P. 登録日 2011-04-05 公開日 2011-08-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Conformation Effects of Base Modification on the Anticodon Stem-Loop of Bacillus subtilis tRNA(Tyr). J.Mol.Biol., 412, 2011
3PY8	Crystal structure of a mutant of the large fragment of DNA polymerase I from thermus aquaticus in a closed ternary complex with DNA and ddCTP 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Schnur, A, Marx, A, Welte, W, Diederichs, K. 登録日 2010-12-12 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity. Chembiochem, 12, 2011
6Q4U	KlenTaq DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*(DOC))-3'), ... 著者 Kropp, H.M, Diederichs, K, Marx, A. 登録日 2018-12-06 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl., 58, 2019
6CYT	HIV-1 TAR loop in complex with Tat:AFF4:P-TEFb 分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... 著者 Schulze Gahmen, U, Hurley, J.H. 登録日 2018-04-06 公開日 2018-12-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4Q8E	Human DNA polymerase eta inserting dCMPNPP opposite a phenanthriplatin adducted G 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3', 5'-D(*CP*AP*TP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3', ... 著者 Gregory, M.T, Yang, W. 登録日 2014-04-26 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.549 Å) 主引用文献 Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage. Proc.Natl.Acad.Sci.USA, 111, 2014
4Q8F	Human DNA polymerase eta extending primer immediately after a phenanthriplatin adducted G 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', ... 著者 Gregory, M.T, Yang, W. 登録日 2014-04-26 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.797 Å) 主引用文献 Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage. Proc.Natl.Acad.Sci.USA, 111, 2014
2PFQ	Manganese promotes catalysis in a DNA polymerase lambda-DNA crystal 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
2PFO	DNA Polymerase lambda in complex with DNA and dUPNPP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007

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