6Q4U

KlenTaq DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP

Summary for 6Q4U

DescriptorDNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*(DOC))-3'), DNA (5'-D(*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (9 entities in total)
Functional Keywordsdna polymerase archaeal b-family modified nucleotide next-generation sequencing, dna binding protein
Biological sourceThermus aquaticus
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Total number of polymer chains3
Total molecular weight70564.84
Authors
Kropp, H.M.,Diederichs, K.,Marx, A. (deposition date: 2018-12-06, release date: 2019-02-27, Last modification date: 2019-08-14)
Primary citation
Kropp, H.M.,Diederichs, K.,Marx, A.
The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide.
Angew.Chem.Int.Ed.Engl., 58:5457-5461, 2019
PubMed: 30761722 (PDB entries with the same primary citation)
DOI: 10.1002/anie.201900315
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.005 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2202 0.2% 1.4% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report