6Q4U
KlenTaq DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA polymerase I, thermostable | polymer | 541 | 61068.2 | 1 | UniProt (P19821) Pfam (PF09281) Pfam (PF00476) In PDB | Thermus aquaticus | Taq polymerase 1 |
| 2 | B | DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*(DOC))-3') | polymer | 12 | 3601.4 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3') | polymer | 16 | 4930.2 | 1 | synthetic construct | ||
| 4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 6 | A | [[(2~{R},3~{S},5~{R})-5-[4-azanyl-5-[3-[2-(2-hydroxyethyloxy)ethanoylamino]prop-1-ynyl]pyrrolo[2,3-d]pyrimidin-7-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 645.3 | 1 | Chemie (HHZ) | |||
| 7 | A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 8 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A: 293 - 832 (UniProt: P19821)
| PDB | External Database | Details |
|---|---|---|
| Met 292 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69599.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 965.1 | |
| All* | Total formula weight | 70564.8 |
