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3PY8

Crystal structure of a mutant of the large fragment of DNA polymerase I from thermus aquaticus in a closed ternary complex with DNA and ddCTP

Summary for 3PY8
Entry DOI10.2210/pdb3py8/pdb
DescriptorDNA polymerase I, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total)
Functional Keywordsmodified klenow fragment, transferase, polymerase, nucleoside binding, nucleic acid binding, dna binding, catalytic activity, dna-directed dna polymerase activity, 5'-3' exonuclease activity, nucleotides, modified nucleotide, artificial nucleotide, nucleotide probes, transferase-dna complex, transferase/dna
Biological sourceThermus aquaticus
Total number of polymer chains3
Total formula weight70466.90
Authors
Schnur, A.,Marx, A.,Welte, W.,Diederichs, K. (deposition date: 2010-12-12, release date: 2011-06-15, Last modification date: 2024-02-21)
Primary citationObeid, S.,Schnur, A.,Gloeckner, C.,Blatter, N.,Welte, W.,Diederichs, K.,Marx, A.
Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity.
Chembiochem, 12:1574-1580, 2011
Cited by
PubMed: 21480455
DOI: 10.1002/cbic.201000783
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.74 Å)
Structure validation

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