3PY8
Crystal structure of a mutant of the large fragment of DNA polymerase I from thermus aquaticus in a closed ternary complex with DNA and ddCTP
Summary for 3PY8
Entry DOI | 10.2210/pdb3py8/pdb |
Descriptor | DNA polymerase I, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total) |
Functional Keywords | modified klenow fragment, transferase, polymerase, nucleoside binding, nucleic acid binding, dna binding, catalytic activity, dna-directed dna polymerase activity, 5'-3' exonuclease activity, nucleotides, modified nucleotide, artificial nucleotide, nucleotide probes, transferase-dna complex, transferase/dna |
Biological source | Thermus aquaticus |
Total number of polymer chains | 3 |
Total formula weight | 70466.90 |
Authors | Schnur, A.,Marx, A.,Welte, W.,Diederichs, K. (deposition date: 2010-12-12, release date: 2011-06-15, Last modification date: 2024-02-21) |
Primary citation | Obeid, S.,Schnur, A.,Gloeckner, C.,Blatter, N.,Welte, W.,Diederichs, K.,Marx, A. Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity. Chembiochem, 12:1574-1580, 2011 Cited by PubMed: 21480455DOI: 10.1002/cbic.201000783 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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