4N56

Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA

Summary for 4N56

• Entry DOI: 10.2210/pdb4n56/pdb
• Related: 4N5S
• Descriptor: 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3', 5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', DNA polymerase I, thermostable, ... (7 entities in total)
• Functional Keywords: dna polymerase, dntp, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus
• Total number of polymer chains: 3
• Total formula weight: 71187.70

Authors

Wu, E.Y. (deposition date: 2013-10-09, release date: 2015-01-21, Last modification date: 2023-09-20)

• Primary citation: Wu, E.Y.,Walsh, A.R.,Materne, E.C.,Hiltner, E.P.,Zielinski, B.,Miller, B.R.,Mawby, L.,Modeste, E.,Parish, C.A.,Barnes, W.M.,Kermekchiev, M.B.; A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase.; Biochemistry, 54:881-889, 2015; PubMed: 25537790; DOI: 10.1021/bi501198f

Experimental method

X-RAY DIFFRACTION (2.2 Å)