KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the third primer nucleotide.

Summary for 6FBE

DescriptorDNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*CP*AP*(OH3)P*CP*C)-3'), DNA (5'-D(*AP*AP*AP*CP*GP*GP*GP*TP*GP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total)
Functional Keywordsdna polymerase, modified nucleotides, klentaq, klentaq dna polymerase, dna binding protein
Biological sourceThermus aquaticus
Total number of polymer chains3
Total molecular weight70513.39
Kropp, H.M.,Diederichs, K.,Marx, A. (deposition date: 2017-12-19, release date: 2018-09-26, Last modification date: 2019-08-14)
Primary citation
Kropp, H.M.,Durr, S.L.,Peter, C.,Diederichs, K.,Marx, A.
Snapshots of a modified nucleotide moving through the confines of a DNA polymerase.
Proc. Natl. Acad. Sci. U.S.A., 115:9992-9997, 2018
PubMed: 30224478 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1811518115
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2031 0.2% 0.2% 3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report