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7ZT2
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BU of 7zt2 by Molmil
Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU
分子名称: 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ...
著者Karuppiah, V, Srikannathasan, V, Robinson, R.A.
登録日2022-05-09
公開日2023-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT3
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BU of 7zt3 by Molmil
Structure of E8 TCR in complex in human MR1 K43A
分子名称: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ...
著者Karuppiah, V, Srikannathasan, V, Robinson, R.A.
登録日2022-05-09
公開日2023-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
3RWE
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BU of 3rwe by Molmil
rhesus macaque MHC class I molecule Mamu-B*17-FW9
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Major histocompatibility complex class I, ...
著者Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F.
登録日2011-05-09
公開日2012-03-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus
J.Immunol., 187, 2011
8HT1
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BU of 8ht1 by Molmil
CRYSTAL STRUCTURE OF A MUTANT MYLU-B-67 FOR 2.4 ANGSTROM, 52M 53Q 54Q 55P 56W DELETED
分子名称: Beta-2-microglobulin, Ig-like domain-containing protein, THR-PRO-GLN-SER-ALA-PRO-HIS-GLY-VAL
著者Wang, S.Q, Zhang, N.Z.
登録日2022-12-20
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CRYSTAL STRUCTURE OF A MUTANT MYLU-B-67 FOR 2.4 ANGSTROM, 52M 53Q 54Q 55P 56W DELETED
To Be Published
6H6D
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BU of 6h6d by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with adenovirus-derived peptide Ad10
分子名称: Beta-2-microglobulin, CHLORIDE ION, Early E1A protein, ...
著者Achour, A, Sandalova, T, Han, X.
登録日2018-07-27
公開日2019-08-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of H-2Db and H-2Dbm13 with cancer-associated Ad 10 peptide reveal that subtle changes in the peptide environment impact thermostability and alloreactivity
to be published
5FKA
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BU of 5fka by Molmil
Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor
分子名称: STAPHYLOCOCCAL ENTEROTOXIN E, T CELL RECEPTOR ALPHA CHAIN, T CELL RECEPTOR BETA CHAIN, ...
著者Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K.
登録日2015-10-15
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Two Common Structural Motifs for Tcr Recognition by Staphylococcal Enterotoxins.
Sci.Rep., 6, 2016
8TUB
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BU of 8tub by Molmil
HLA B7:02 with HPNGYKSLSTL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J.
登録日2023-08-16
公開日2024-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.
Nat Commun, 15, 2024
3MNV
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BU of 3mnv by Molmil
Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment
分子名称: 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ...
著者Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F.
登録日2010-04-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.
Nat.Struct.Mol.Biol., 17, 2010
3S4S
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BU of 3s4s by Molmil
Crystal structure of CD4 mutant bound to HLA-DR1
分子名称: GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Li, Y.
登録日2011-05-20
公開日2011-09-21
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
2NTS
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BU of 2nts by Molmil
Crystal Structure of SEK-hVb5.1
分子名称: Staphylococcal enterotoxin K, TRBC1 protein
著者Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J.
登録日2006-11-08
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
3MRH
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BU of 3mrh by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide N3S variant
分子名称: 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Gras, S, Reiser, J.-B, Chouquet, A, Le Gorrec, M, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
2YPL
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BU of 2ypl by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
分子名称: AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ...
著者Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
登録日2012-10-30
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
1NGQ
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BU of 1ngq by Molmil
N1G9 (IGG1-LAMBDA) FAB FRAGMENT
分子名称: N1G9 (IGG1-LAMBDA), SULFATE ION
著者Mizutani, R, Satow, Y.
登録日1995-06-23
公開日1996-07-11
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.
J.Mol.Biol., 254, 1995
3WEX
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BU of 3wex by Molmil
Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen
著者Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S.
登録日2013-07-16
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014
1KLG
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BU of 1klg by Molmil
Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
分子名称: ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
著者Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A.
登録日2001-12-11
公開日2002-08-02
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
7URU
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BU of 7uru by Molmil
Crystal structure of the low affinity Fc gamma receptor IIIA variant in complex with the Fc of IgG1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, ...
著者Tolbert, W.D, Pazgier, M.
登録日2022-04-22
公開日2023-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the low affinity Fc gamma receptor IIIA variant in complex with the Fc of IgG1.
To Be Published
8GQV
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BU of 8gqv by Molmil
The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus
分子名称: As64, MHC class I antigen, beta 2 microglobulin
著者Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S.
登録日2022-08-31
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development.
Cells, 11, 2022
6BIL
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BU of 6bil by Molmil
HLA-DRB1 in complex with citrullinated fibrinogen peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 74cit69-81, HLA class II histocompatibility antigen, ...
著者Ting, Y.T, Scally, S.W, Rossjohn, J.
登録日2017-11-02
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6UGV
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BU of 6ugv by Molmil
Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C
分子名称: 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ...
著者Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
登録日2019-09-26
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
5FA4
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BU of 5fa4 by Molmil
Structure of HLA-A2:01 with peptide Y16R
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-12-10
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
1S7W
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BU of 1s7w by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
2VLJ
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BU of 2vlj by Molmil
The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
分子名称: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y.
登録日2008-01-15
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
7KP0
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BU of 7kp0 by Molmil
CD1a-42:1 SM binary complex
分子名称: (4R,7S)-4-hydroxy-7-[(1S,2E)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-4,9-dioxo-3,5-dioxa-8-aza-4lambda~5~-phosphadotriacontan-1-aminium, 1,2-ETHANEDIOL, Beta-2-microglobulin, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2020-11-10
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CD1a selectively captures endogenous cellular lipids that broadly block T cell response.
J.Exp.Med., 218, 2021
5C9J
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BU of 5c9j by Molmil
Human CD1c with ligands in A' and F' channel
分子名称: Beta-2-microglobulin, GLYCEROL, LAURIC ACID, ...
著者Tews, I, Machelett, M.M, Mansour, S, Gadola, S.D.
登録日2015-06-27
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.
Proc.Natl.Acad.Sci.USA, 113, 2016
1SYS
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BU of 1sys by Molmil
Crystal structure of HLA, B*4403, and peptide EEPTVIKKY
分子名称: Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule
著者Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J.
登録日2004-04-01
公開日2004-10-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200, 2004

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