7ZT2
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![BU of 7zt2 by Molmil](/molmil-images/mine/7zt2) | Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ... | 著者 | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | 登録日 | 2022-05-09 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT3
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![BU of 7zt3 by Molmil](/molmil-images/mine/7zt3) | Structure of E8 TCR in complex in human MR1 K43A | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ... | 著者 | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | 登録日 | 2022-05-09 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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3RWE
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![BU of 3rwe by Molmil](/molmil-images/mine/3rwe) | rhesus macaque MHC class I molecule Mamu-B*17-FW9 | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Major histocompatibility complex class I, ... | 著者 | Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. | 登録日 | 2011-05-09 | 公開日 | 2012-03-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus J.Immunol., 187, 2011
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8HT1
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![BU of 8ht1 by Molmil](/molmil-images/mine/8ht1) | |
6H6D
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![BU of 6h6d by Molmil](/molmil-images/mine/6h6d) | |
5FKA
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![BU of 5fka by Molmil](/molmil-images/mine/5fka) | Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | 分子名称: | STAPHYLOCOCCAL ENTEROTOXIN E, T CELL RECEPTOR ALPHA CHAIN, T CELL RECEPTOR BETA CHAIN, ... | 著者 | Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K. | 登録日 | 2015-10-15 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Two Common Structural Motifs for Tcr Recognition by Staphylococcal Enterotoxins. Sci.Rep., 6, 2016
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8TUB
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![BU of 8tub by Molmil](/molmil-images/mine/8tub) | HLA B7:02 with HPNGYKSLSTL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J. | 登録日 | 2023-08-16 | 公開日 | 2024-03-13 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age. Nat Commun, 15, 2024
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3MNV
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![BU of 3mnv by Molmil](/molmil-images/mine/3mnv) | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment | 分子名称: | 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ... | 著者 | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | 登録日 | 2010-04-22 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region. Nat.Struct.Mol.Biol., 17, 2010
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3S4S
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![BU of 3s4s by Molmil](/molmil-images/mine/3s4s) | Crystal structure of CD4 mutant bound to HLA-DR1 | 分子名称: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Li, Y. | 登録日 | 2011-05-20 | 公開日 | 2011-09-21 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
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2NTS
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![BU of 2nts by Molmil](/molmil-images/mine/2nts) | Crystal Structure of SEK-hVb5.1 | 分子名称: | Staphylococcal enterotoxin K, TRBC1 protein | 著者 | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | 登録日 | 2006-11-08 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel loop domain in superantigens extends their T cell receptor recognition site J.Mol.Biol., 371, 2007
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3MRH
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![BU of 3mrh by Molmil](/molmil-images/mine/3mrh) | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide N3S variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Reiser, J.-B, Chouquet, A, Le Gorrec, M, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
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2YPL
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![BU of 2ypl by Molmil](/molmil-images/mine/2ypl) | Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms | 分子名称: | AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ... | 著者 | Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M. | 登録日 | 2012-10-30 | 公開日 | 2012-11-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms. Proc.Natl.Acad.Sci.USA, 109, 2012
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1NGQ
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![BU of 1ngq by Molmil](/molmil-images/mine/1ngq) | N1G9 (IGG1-LAMBDA) FAB FRAGMENT | 分子名称: | N1G9 (IGG1-LAMBDA), SULFATE ION | 著者 | Mizutani, R, Satow, Y. | 登録日 | 1995-06-23 | 公開日 | 1996-07-11 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate. J.Mol.Biol., 254, 1995
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3WEX
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![BU of 3wex by Molmil](/molmil-images/mine/3wex) | Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | 著者 | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | 登録日 | 2013-07-16 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5 J. Mol. Biol., 426, 2014
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1KLG
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![BU of 1klg by Molmil](/molmil-images/mine/1klg) | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | 分子名称: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | 著者 | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | 登録日 | 2001-12-11 | 公開日 | 2002-08-02 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. J.Mol.Biol., 319, 2002
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7URU
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![BU of 7uru by Molmil](/molmil-images/mine/7uru) | Crystal structure of the low affinity Fc gamma receptor IIIA variant in complex with the Fc of IgG1. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, ... | 著者 | Tolbert, W.D, Pazgier, M. | 登録日 | 2022-04-22 | 公開日 | 2023-04-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the low affinity Fc gamma receptor IIIA variant in complex with the Fc of IgG1. To Be Published
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8GQV
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![BU of 8gqv by Molmil](/molmil-images/mine/8gqv) | The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus | 分子名称: | As64, MHC class I antigen, beta 2 microglobulin | 著者 | Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S. | 登録日 | 2022-08-31 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development. Cells, 11, 2022
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6BIL
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![BU of 6bil by Molmil](/molmil-images/mine/6bil) | HLA-DRB1 in complex with citrullinated fibrinogen peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 74cit69-81, HLA class II histocompatibility antigen, ... | 著者 | Ting, Y.T, Scally, S.W, Rossjohn, J. | 登録日 | 2017-11-02 | 公開日 | 2018-01-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. J. Biol. Chem., 293, 2018
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6UGV
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![BU of 6ugv by Molmil](/molmil-images/mine/6ugv) | Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C | 分子名称: | 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ... | 著者 | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | 登録日 | 2019-09-26 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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5FA4
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![BU of 5fa4 by Molmil](/molmil-images/mine/5fa4) | Structure of HLA-A2:01 with peptide Y16R | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Remesh, S.G, Zajonc, D.M. | 登録日 | 2015-12-10 | 公開日 | 2016-12-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT. J. Biol. Chem., 292, 2017
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1S7W
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![BU of 1s7w by Molmil](/molmil-images/mine/1s7w) | Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants | 分子名称: | Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ... | 著者 | Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A. | 登録日 | 2004-01-30 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol., 172, 2004
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2VLJ
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![BU of 2vlj by Molmil](/molmil-images/mine/2vlj) | The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain | 分子名称: | BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y. | 登録日 | 2008-01-15 | 公開日 | 2008-01-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain Immunity, 28, 2008
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7KP0
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![BU of 7kp0 by Molmil](/molmil-images/mine/7kp0) | CD1a-42:1 SM binary complex | 分子名称: | (4R,7S)-4-hydroxy-7-[(1S,2E)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-4,9-dioxo-3,5-dioxa-8-aza-4lambda~5~-phosphadotriacontan-1-aminium, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2020-11-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
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5C9J
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![BU of 5c9j by Molmil](/molmil-images/mine/5c9j) | Human CD1c with ligands in A' and F' channel | 分子名称: | Beta-2-microglobulin, GLYCEROL, LAURIC ACID, ... | 著者 | Tews, I, Machelett, M.M, Mansour, S, Gadola, S.D. | 登録日 | 2015-06-27 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells. Proc.Natl.Acad.Sci.USA, 113, 2016
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1SYS
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![BU of 1sys by Molmil](/molmil-images/mine/1sys) | Crystal structure of HLA, B*4403, and peptide EEPTVIKKY | 分子名称: | Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule | 著者 | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | 登録日 | 2004-04-01 | 公開日 | 2004-10-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion J.Exp.Med., 200, 2004
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