PDB: 47720 件ウェブページステータス検索Chemie searchBIRD

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7KN5	Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. 登録日 2020-11-04 公開日 2021-01-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
6AXL	Crystal structure of Fab317 complex 分子名称: Fab317 heavy chain, Fab317 light chains, Peptide ACE-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-NH2 著者 Oyen, D, Wilson, I.A. 登録日 2017-09-07 公開日 2017-11-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5MZ2	Rubisco from Thalassiosira antarctica 分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Andersson, I, Valegard, K. 登録日 2017-01-30 公開日 2018-02-14 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications. J. Biol. Chem., 293, 2018
5N47	Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin 分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin 著者 Schiefner, A, Skerra, A. 登録日 2017-02-10 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen. Structure, 26, 2018
6B8C	Crystal structure of NlpC/p60 domain of peptidoglycan hydrolase SagA 分子名称: NLP/P60 著者 Kim, B, Oren, D.A, Hang, H.C. 登録日 2017-10-06 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Enterococcus faeciumsecreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis. Elife, 8, 2019
5N5E	Crystal structure of encapsulated ferritin domain from Pyrococcus furiosus PFC_05175 分子名称: FE (III) ION, PFC_05175 著者 Marles-Wright, J, He, D. 登録日 2017-02-13 公開日 2018-01-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.026 Å) 主引用文献 Conservation of the structural and functional architecture of encapsulated ferritins in bacteria and archaea. Biochem.J., 476, 2019
2PG7	Crystal Structure of Human Microsomal P450 2A6 N297Q/I300V 分子名称: Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE 著者 Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F. 登録日 2007-04-06 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch.Biochem.Biophys., 464, 2007
6BFT	Structure of Bevacizumab Fab mutant in complex with VEGF 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Avastin Heavy Chain Fab fragment mutant, Avastin Light Chain Fab fragment mutant, ... 著者 Christie, M, Christ, D. 登録日 2017-10-27 公開日 2018-10-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Stable human IgG antibody therapeutics with native framework structure To Be Published
2PFF	Structural Insights of Yeast Fatty Acid Synthase 分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Tail protein 著者 Xiong, Y, Lomakin, I.B, Steitz, T.A. 登録日 2007-04-04 公開日 2007-07-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural Insights of Yeast Fatty Acid Synthase Cell(Cambridge,Mass.), 129, 2007
2PI4	T7RNAP complexed with a phi10 protein and initiating GTPs. 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*CP*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', ... 著者 Kennedy, W.P, Momand, J.R, Yin, Y.W. 登録日 2007-04-12 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase. J.Mol.Biol., 370, 2007
5N3F	cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule N-[3-(aminomethyl)phenyl]acetamide 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, N-[3-(aminomethyl)phenyl]acetamide, cAMP dependent protein kinase inhibitor alpha-like protein, ... 著者 Siefker, C, Heine, A, Klebe, G. 登録日 2017-02-08 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 A crystallographic fragment study with cAMP-dependent protein kinase A To Be Published
2PWL	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome. 分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION 著者 Chen, H, Mohammadi, M. 登録日 2007-05-11 公開日 2007-09-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. 登録日 2017-10-02 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of bacterial transcription activation. Science, 358, 2017
2PGQ	Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... 著者 Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. 登録日 2007-04-10 公開日 2007-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282, 2007
5MYU	VipA-N2/VipB contracted sheath of type VI secretion system 分子名称: Type VI secretion system protein ImpC, Uncharacterized protein 著者 Wang, J, Brackmann, B, Castano-Diez, D, Kudryashev, M, Goldie, D, Maier, T, Stahlberg, H, Basler, M. 登録日 2017-01-27 公開日 2017-08-02 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of the extended type VI secretion system sheath-tube complex. Nat Microbiol, 2, 2017
2PZV	Crystal Structure of Ketosteroid Isomerase D40N from Pseudomonas Putida (pksi) with bound Phenol 分子名称: PHENOL, Steroid Delta-isomerase 著者 Pybus, B, Caaveiro, J.M.M, Petsko, G.A, Ringe, D. 登録日 2007-05-18 公開日 2007-06-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Testing Electrostatic complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole PLoS Biol., 4, 2006
2PVF	Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide 分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Chen, H, Mohammadi, M. 登録日 2007-05-09 公開日 2007-09-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PNH	Escherichia coli PriB E39A variant 分子名称: Primosomal replication protein n 著者 Lopper, M.E, Keck, J.L. 登録日 2007-04-24 公開日 2007-08-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A hand-off mechanism for primosome assembly in replication restart. Mol.Cell, 26, 2007
7JG8	Cryo-EM structure of bedaquiline-saturated Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model) 分子名称: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... 著者 Guo, H, Courbon, G.M, Rubinstein, J.L. 登録日 2020-07-18 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589, 2021
7ICK	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF MGCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
7ICG	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CDCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
7ICQ	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
3FFW	Crystal Structure of CheY triple mutant F14Q, N59K, E89Y complexed with BeF3- and Mn2+ 分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein cheY, GLYCEROL, ... 著者 Pazy, Y, Collins, E.J, Bourret, R.B. 登録日 2008-12-04 公開日 2009-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Matching Biochemical Reaction Kinetics to the Timescales of Life: Structural Determinants That Influence the Autodephosphorylation Rate of Response Regulator Proteins. J.Mol.Biol., 392, 2009
2PY7	Crystal structure of E. coli phosphoenolpyruvate carboxykinase mutant Lys213Ser complexed with ATP-Mg2+-Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Delbaere, L.T.J, Cotelesage, J.J.H, Goldie, H. 登録日 2007-05-15 公開日 2008-04-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of E. coli phosphoenolpyruvate carboxykinase mutant Lys213Ser To be Published
7JGA	Cryo-EM structure of bedaquiline-saturated Mycobacterium smegmatis ATP synthase rotational state 3 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Guo, H, Courbon, G.M, Rubinstein, J.L. 登録日 2020-07-18 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589, 2021

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