7JG8

Cryo-EM structure of bedaquiline-saturated Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model)

Summary for 7JG8

Entry DOI	10.2210/pdb7jg8/pdb
EMDB information	22311 22312 22313 22314 22315 22316 22317 22318 22319 22320 22321 22322
Descriptor	ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase gamma chain, ... (9 entities in total)
Functional Keywords	bedaquiline, sirturo, tmc207, t207910, atp synthase, mycobacteria, tuberculosis, hydrolase
Biological source	Mycolicibacterium smegmatis More
Total number of polymer chains	20
Total formula weight	552563.60
Authors	Guo, H.,Courbon, G.M.,Rubinstein, J.L. (deposition date: 2020-07-18, release date: 2020-08-19, Last modification date: 2024-03-06)
Primary citation	Guo, H.,Courbon, G.M.,Bueler, S.A.,Mai, J.,Liu, J.,Rubinstein, J.L. Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589:143-147, 2021 Cited by PubMed: 33299175 DOI: 10.1038/s41586-020-3004-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation