2OCC
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6CRI
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | 分子名称: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | 著者 | Morris, K.L, Buffalo, C.Z, Hurley, J.H. | 登録日 | 2018-03-18 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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5BNP
| Crystal structure of human enterovirus D68 in complex with 3'SLN | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G. | 登録日 | 2015-05-26 | 公開日 | 2015-11-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Sialic acid-dependent cell entry of human enterovirus D68. Nat Commun, 6, 2015
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5BOY
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6BGL
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2C36
| Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry | 分子名称: | CHLORIDE ION, GLYCOPROTEIN D HSV-1, ZINC ION, ... | 著者 | Krummenacher, C, Supekar, V.M, Whitbeck, J.C, Lazear, E, Connolly, S.A, Eisenberg, R.J, Cohen, G.H, Wiley, D.C, Carfi, A. | 登録日 | 2005-10-04 | 公開日 | 2005-11-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry. EMBO J., 24, 2005
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6BGO
| Singly PafE-capped 20S CP in Mycobacterium tuberculosis | 分子名称: | Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta | 著者 | Li, H, Hu, K. | 登録日 | 2017-10-29 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Proteasome substrate capture and gate opening by the accessory factor PafE fromMycobacterium tuberculosis. J. Biol. Chem., 293, 2018
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2BMY
| Banana Lectin | 分子名称: | CADMIUM ION, RIPENING-ASSOCIATED PROTEIN, SULFATE ION | 著者 | Meagher, J.L, Winter, H.C, Ezell, P, Goldstein, I.J, Stuckey, J.A. | 登録日 | 2005-03-17 | 公開日 | 2005-06-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Banana Lectin Reveals a Novel Second Sugar Binding Site. Glycobiology, 15, 2005
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2PGQ
| Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... | 著者 | Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. | 登録日 | 2007-04-10 | 公開日 | 2007-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282, 2007
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2PZV
| Crystal Structure of Ketosteroid Isomerase D40N from Pseudomonas Putida (pksi) with bound Phenol | 分子名称: | PHENOL, Steroid Delta-isomerase | 著者 | Pybus, B, Caaveiro, J.M.M, Petsko, G.A, Ringe, D. | 登録日 | 2007-05-18 | 公開日 | 2007-06-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Testing Electrostatic complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole PLoS Biol., 4, 2006
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6CKS
| Crystal Structure of BRD4 with QC4956 | 分子名称: | 4-[5-(ethylsulfonyl)-2-methoxyphenyl]-2-methyl-6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-1(2H)-one, Bromodomain-containing protein 4 | 著者 | Hosfield, D.J. | 登録日 | 2018-02-28 | 公開日 | 2018-05-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors. Bioorg. Med. Chem. Lett., 28, 2018
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5AFK
| alpha7-AChBP in complex with lobeline and fragment 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE-BINDING PROTEIN, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7, ... | 著者 | Spurny, R, Debaveye, S, Farinha, A, Veys, K, Gossas, T, Atack, J, Bertrand, D, Kemp, J, Vos, A, Danielson, U.H, Tresadern, G, Ulens, C. | 登録日 | 2015-01-22 | 公開日 | 2015-05-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | 主引用文献 | Molecular Blueprint of Allosteric Binding Sites in a Homologue of the Agonist-Binding Domain of the Alpha7 Nicotinic Acetylcholine Receptor. Proc.Natl.Acad.Sci.USA, 112, 2015
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5AGW
| Bcl-2 alpha beta-1 complex | 分子名称: | APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1, BCL-2-LIKE PROTEIN 11 | 著者 | Smith, B.J, F Lee, E, Checco, J.W, Gellman, S.H, Fairlie, W.D. | 登録日 | 2015-02-04 | 公開日 | 2015-09-09 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.695 Å) | 主引用文献 | Alpha Beta Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity on Living Cells J.Am.Chem.Soc., 137, 2015
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2PNH
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6CCE
| Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A | 分子名称: | 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2018-02-07 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
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2CKY
| Structure of the Arabidopsis thaliana thiamine pyrophosphate riboswitch with its regulatory ligand | 分子名称: | MAGNESIUM ION, NUCLEIC ACID, OSMIUM ION, ... | 著者 | Thore, S, Leibundgut, M, Ban, N. | 登録日 | 2006-04-24 | 公開日 | 2006-05-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the Eukaryotic Thiamine Pyrophosphate Riboswitch with its Regulatory Ligand. Science, 312, 2006
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6CCV
| Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin | 分子名称: | 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2018-02-07 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
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2BV6
| Crystal structure of MgrA, a global regulator and major virulence determinant in Staphylococcus aureus | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR MGRA, SULFATE ION | 著者 | Chen, P.R, Bae, T, Williams, W.A, Duguid, E.M, Rice, P.A, Schneewind, O, He, C. | 登録日 | 2005-06-22 | 公開日 | 2006-09-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An Oxidation-Sensing Mechanism is Used by the Global Regulator Mgra in Staphylococcus Aureus. Nat.Chem.Biol., 2, 2006
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2O6V
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2O4U
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2O5I
| Crystal structure of the T. thermophilus RNA polymerase elongation complex | 分子名称: | 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... | 著者 | Vassylyev, D.G, Tahirov, T.H, Vassylyeva, M.N. | 登録日 | 2006-12-06 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for transcription elongation by bacterial RNA polymerase. Nature, 448, 2007
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2BF8
| Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K | 分子名称: | UBIQUITIN-CONJUGATING ENZYME E2-25 KDA, UBIQUITIN-LIKE PROTEIN SMT3C | 著者 | Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. | 登録日 | 2004-12-06 | 公開日 | 2005-02-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K Nat.Struct.Mol.Biol., 12, 2005
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5A3X
| DYRK1A in complex with hydroxy benzothiazole fragment | 分子名称: | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A, N-(5-oxidanyl-1,3-benzothiazol-2-yl)ethanamide | 著者 | Rothweiler, U. | 登録日 | 2015-06-03 | 公開日 | 2016-06-29 | 最終更新日 | 2019-02-06 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Probing the ATP-Binding Pocket of Protein Kinase Dyrk1A with Benzothiazole Fragment Molecules J.Med.Chem., 59, 2016
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2OD3
| Human thrombin chimera with human residues 184a, 186, 186a, 186b, 186c and 222 replaced by murine thrombin equivalents. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... | 著者 | Marino, F, Chen, Z, Ergenekan, C.E, Bush, L.A, Mathews, F.S, Di Cera, E. | 登録日 | 2006-12-21 | 公開日 | 2007-04-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis of na+ activation mimicry in murine thrombin. J.Biol.Chem., 282, 2007
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2OAU
| Mechanosensitive Channel of Small Conductance (MscS) | 分子名称: | Small-conductance mechanosensitive channel | 著者 | Rees, D.C, Bass, R.B, Steinbacher, S, Strop, P, Barclay, M.T. | 登録日 | 2006-12-17 | 公開日 | 2007-01-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structures of the Prokaryotic Mechanosensitive Channels MscL and MscS CURRENT TOPICS IN MEMBRANES, 58, 2007
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