PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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6A5Z	Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC180 and 9cRA and SRC1 分子名称: (9cis)-retinoic acid, 2-[(1R,5S)-9-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-3-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, ... 著者 Wang, N, Liu, J. 登録日 2018-06-25 公開日 2018-10-10 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
5WQ7	CryoEM structure of type II secretion system secretin GspD in E.coli K12 分子名称: Putative type II secretion system protein D 著者 Yan, Z, Yin, M, Li, X. 登録日 2016-11-23 公開日 2016-12-28 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structural insights into the secretin translocation channel in the type II secretion system Nat. Struct. Mol. Biol., 24, 2017
2DUF	crystal structure of a green fluorescent protein variant S65T/H148D at pH 5.6 分子名称: Green fluorescent protein 著者 Shu, X, Remington, S.J. 登録日 2006-07-23 公開日 2007-07-10 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Ultrafast excited-state dynamics in the green fluorescent protein variant S65T/H148D. 1. Mutagenesis and structural studies. Biochemistry, 46, 2007
5WTQ	Crystal structure of human proteasome-assembling chaperone PAC4 分子名称: CHLORIDE ION, NICKEL (II) ION, Proteasome assembly chaperone 4 著者 Kurimoto, E, Satoh, T, Ito, Y, Ishihara, E, Tanaka, K, Kato, K. 登録日 2016-12-13 公開日 2017-03-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human proteasome assembly chaperone PAC4 involved in proteasome formation Protein Sci., 26, 2017
5W9O	MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 分子名称: G4 VH, G4 VL, Spike glycoprotein 著者 Pallesen, J, Ward, A.B. 登録日 2017-06-23 公開日 2017-08-16 最終更新日 2020-01-01 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ZRF	Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA and etoposide in space group p21 分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, ... 著者 Chen, S.F, Wang, Y.R, Wu, C.C, Chan, N.L. 登録日 2018-04-24 公開日 2018-08-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate. Nat Commun, 9, 2018
5WUA	Structure of a Pancreatic ATP-sensitive Potassium Channel 分子名称: ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1 著者 Li, N, Wu, J.-X, Chen, L, Gao, N. 登録日 2016-12-16 公開日 2017-01-25 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Structure of a Pancreatic ATP-Sensitive Potassium Channel Cell, 168, 2017
5WYQ	Crystal Structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa 分子名称: S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase 著者 Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W, McBee, M.E, Maenpuen, S, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M, Chaiyen, P. 登録日 2017-01-15 公開日 2017-12-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa. Rna, 2019
5B2Y	Crystal Structure of P450BM3 with N-perfluorodecanoyl-L-tryptophan 分子名称: (2~{S})-3-(1~{H}-indol-3-yl)-2-[2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecakis(fluoranyl)decanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Cong, Z, Shoji, O, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y. 登録日 2016-02-07 公開日 2017-02-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal Structure of P450BM3 with decoy molecules to be published
2MPH	Solution Structure of human FK506 binding Protein 25 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP3 著者 Shin, J, Prakash, A, Yoon, H. 登録日 2014-05-18 公開日 2015-05-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin. Nucleic Acids Res., 44, 2016
5WEM	GluA2 bound to GSG1L in digitonin, state 1 分子名称: Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein 著者 Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. 登録日 2017-07-10 公開日 2017-08-02 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
5W9I	MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ... 著者 Pallesen, J, Ward, A.B. 登録日 2017-06-23 公開日 2017-08-16 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6A5N	Crystal structure of Arabidopsis thaliana SUVH6 in complex with methylated DNA 分子名称: DNA (5'-D(*CP*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, ... 著者 Li, X, Du, J. 登録日 2018-06-24 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5WBX	Structural insights into the potency of SK/IK channel positive modulators 分子名称: (3Z)-6-bromo-3-(hydroxyimino)-5-methyl-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ... 著者 Nam, Y.W, Zhang, M. 登録日 2017-06-29 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the potency of SK channel positive modulators. Sci Rep, 7, 2017
5WC5	Structural insights into the potency of SK/IK channel positive modulators 分子名称: 7-fluoro-3-(hydroxyamino)-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ... 著者 Nam, Y.W, Zhang, M. 登録日 2017-06-29 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the potency of SK channel positive modulators. Sci Rep, 7, 2017
2MT8	Solution structure MTAbl13, a grafted MCoTI-II 分子名称: MTAbl13 of grafted MCoTI-II 著者 Huang, Y, Wang, C, Craik, D. 登録日 2014-08-15 公開日 2015-10-14 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Sci Rep, 5, 2015
5WI4	CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2 分子名称: Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION 著者 Balan, M, Ishiyama, N, Marshall, C.B, Ikura, M. 登録日 2017-07-18 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity. Sci Signal, 10, 2017
5WK7	P450cam mutant R186A 分子名称: 5-EXO-HYDROXYCAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Batabyal, D, Poulos, T.L. 登録日 2017-07-24 公開日 2017-09-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.983 Å) 主引用文献 Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics. J. Am. Chem. Soc., 139, 2017
5WKA	Crystal structure of a GH1 beta-glucosidase retrieved from microbial metagenome of Poraque Amazon lake 分子名称: Beta-glucosidase, DI(HYDROXYETHYL)ETHER, GLYCEROL 著者 Morais, M.A.B, Toyama, D, Ramos, F.C, Zanphorlin, L.M, Tonoli, C.C.C, Miranda, F.P, Ruller, R, Henrique-Silva, F, Murakami, M.T. 登録日 2017-07-24 公開日 2018-03-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 A novel beta-glucosidase isolated from the microbial metagenome of Lake Poraque (Amazon, Brazil). Biochim. Biophys. Acta, 1866, 2018
2N1W	Solution structure of human SUMO2 分子名称: Small ubiquitin-related modifier 2 著者 Naik, M.T, Naik, N, Shih, H, Huang, T. 登録日 2015-04-24 公開日 2016-04-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structures of human SUMO To Be Published
2MWT	NMR structure of crotalicidin in DPC micelles 分子名称: Cathelicidin-like peptide 著者 Jimenez, M, Zamora-Carreras, H. 登録日 2014-11-24 公開日 2015-11-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. J.Med.Chem., 58, 2015
6ALG	CryoEM structure of HK022 Nun - E.coli RNA polymerase elongation complex 分子名称: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Kang, J.Y, Darst, S.A. 登録日 2017-08-07 公開日 2017-08-16 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of transcription arrest by coliphage HK022 Nun in anEscherichia coliRNA polymerase elongation complex. Elife, 6, 2017
5WQ9	CryoEM structure of type II secretion system secretin GspD G453A mutant in Vibrio cholerae 分子名称: Type II secretion system protein D 著者 Yan, Z, Yin, M, Li, X. 登録日 2016-11-23 公開日 2016-12-28 最終更新日 2017-02-22 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 Structural insights into the secretin translocation channel in the type II secretion system Nat. Struct. Mol. Biol., 24, 2017
5B2U	Crystal Structure of P450BM3 with N-perfluorohexanoyl -L-tryptophan 分子名称: (2~{S})-3-(1~{H}-indol-3-yl)-2-[2,2,3,3,4,4,5,5,6,6,6-undecakis(fluoranyl)hexanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, ... 著者 Cong, Z, Shoji, O, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y. 登録日 2016-02-03 公開日 2017-02-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of P450BM3 with decoy molecules to be published
5W7M	Crystal structure of RoqN 分子名称: Glandicoline B O-methyltransferase roqN, S-ADENOSYL-L-HOMOCYSTEINE 著者 Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H. 登録日 2017-06-20 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Org. Biomol. Chem., 16, 2018

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