6KMT
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![BU of 6kmt by Molmil](/molmil-images/mine/6kmt) | P32 of caspase-11 mutant C254A | 分子名称: | Caspase-4 | 著者 | Ding, J, Sun, Q. | 登録日 | 2019-08-01 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020
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6KMO
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6KMU
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5WRE
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![BU of 5wre by Molmil](/molmil-images/mine/5wre) | Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01) | 分子名称: | (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ... | 著者 | Zhou, Z, Xu, Z.H. | 登録日 | 2016-12-01 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.946 Å) | 主引用文献 | Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms. Sci Rep, 7, 2017
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6KI0
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![BU of 6ki0 by Molmil](/molmil-images/mine/6ki0) | Crystal Structure of Human ASC-CARD | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Xu, Z.H, Jin, T.C. | 登録日 | 2019-07-16 | 公開日 | 2020-07-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome. Cell Death Dis, 12, 2021
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6KMV
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7NBG
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![BU of 7nbg by Molmil](/molmil-images/mine/7nbg) | Crystal structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen. | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, ... | 著者 | Koulouris, C.R, Roe, S.M. | 登録日 | 2021-01-26 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7NBH
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![BU of 7nbh by Molmil](/molmil-images/mine/7nbh) | Crystal structure of human serine racemase in complex with DSiP fragment Z26781964, XChem fragment screen. | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Koulouris, C.R, Roe, S.M. | 登録日 | 2021-01-26 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7NBD
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![BU of 7nbd by Molmil](/molmil-images/mine/7nbd) | Crystal structure of human serine racemase in complex with DSiP fragment Z235449082, XChem fragment screen. | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | 著者 | Koulouris, C.R, Roe, S.M. | 登録日 | 2021-01-26 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.865 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7NBC
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![BU of 7nbc by Molmil](/molmil-images/mine/7nbc) | Crystal structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen. | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, ... | 著者 | Koulouris, C.R, Roe, S.M. | 登録日 | 2021-01-26 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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7NBF
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![BU of 7nbf by Molmil](/molmil-images/mine/7nbf) | Crystal structure of human serine racemase in complex with DSiP fragment Z126932614, XChem fragment screen. | 分子名称: | 1,2-ETHANEDIOL, 2-[(methylsulfonyl)methyl]-1H-benzimidazole, CALCIUM ION, ... | 著者 | Koulouris, C.R, Roe, S.M. | 登録日 | 2021-01-26 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
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6RBF
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![BU of 6rbf by Molmil](/molmil-images/mine/6rbf) | Mucin 2 D3 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2019-04-10 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains. J.Mol.Biol., 431, 2019
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7NBI
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8OOL
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5IBP
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![BU of 5ibp by Molmil](/molmil-images/mine/5ibp) | Caspase 3 V266M | 分子名称: | ACE-ASP-GLU-VAL-ASK, AZIDE ION, Caspase-3 | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-22 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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1NHA
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![BU of 1nha by Molmil](/molmil-images/mine/1nha) | Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP-Binding Sites of RAP74 and CTD of RAP74, the subunit of Human TFIIF | 分子名称: | Transcription initiation factor IIF, alpha subunit | 著者 | Nguyen, B.D, Chen, H.T, Kobor, M.S, Greenblatt, J, Legault, P, Omichinski, J.G. | 登録日 | 2002-12-19 | 公開日 | 2003-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB. Biochemistry, 42, 2003
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5I9B
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![BU of 5i9b by Molmil](/molmil-images/mine/5i9b) | Caspase 3 V266A | 分子名称: | ACE-ASP-GLU-VAL-ASK, Caspase-3, SODIUM ION | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-19 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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5EPP
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![BU of 5epp by Molmil](/molmil-images/mine/5epp) | Structural Insights into the Interaction of p97 N-terminus Domain and VBM Motif in Rhomboid Protease, RHBDL4 | 分子名称: | Rhomboid-related protein 4, Transitional endoplasmic reticulum ATPase | 著者 | Lim, J.J, Lee, Y, Ly, T.T, Kang, J.Y, Lee, J.-G, An, J.Y, Youn, H.-S, Park, K.R, Kim, T.G, Yang, J.K, Jun, Y, Eom, S.H. | 登録日 | 2015-11-12 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4. Biochem.J., 473, 2016
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5IBC
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![BU of 5ibc by Molmil](/molmil-images/mine/5ibc) | Caspase 3 V266I | 分子名称: | ACE-ASP-GLU-VAL-ASK, Caspase-3, SODIUM ION | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-22 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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5EFR
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6I3M
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![BU of 6i3m by Molmil](/molmil-images/mine/6i3m) | eIF2B:eIF2 complex, phosphorylated on eIF2 alpha serine 52. | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | 著者 | Adomavicius, T, Roseman, A.M, Pavitt, G.D. | 登録日 | 2018-11-06 | 公開日 | 2019-05-22 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | The structural basis of translational control by eIF2 phosphorylation. Nat Commun, 10, 2019
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5BMU
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5IAR
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![BU of 5iar by Molmil](/molmil-images/mine/5iar) | Caspase 3 V266W | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACE-ASP-GLU-VAL-ASK, Caspase-3, ... | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-21 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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5I9T
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![BU of 5i9t by Molmil](/molmil-images/mine/5i9t) | Caspase 3 V266C | 分子名称: | ACE-ASP-GLU-VAL-ASK, ACETATE ION, Caspase-3 | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-20 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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5IAE
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![BU of 5iae by Molmil](/molmil-images/mine/5iae) | Caspase 3 V266F | 分子名称: | ACE-ASP-GLU-VAL-ASK, ACETATE ION, CHLORIDE ION, ... | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-21 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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