8SLT
 
 | | Crystal structure of human STEP (PTPN5) at physiological temperature (310 K) and ambient pressure (0.1 MPa) | | 分子名称: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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8SLS
 | | Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and ambient pressure (0.1 MPa) | | 分子名称: | GLYCEROL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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8SLQ
 | | Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-3 | | 分子名称: | Transient receptor potential cation channel subfamily M member 5 | | 著者 | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | 登録日 | 2023-04-24 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SLP
 | | Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-2 | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 5 | | 著者 | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | 登録日 | 2023-04-24 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SLO
 | | Plasmodium falciparum M1 aminopeptidase bound to selective inhibitor MIPS2673 | | 分子名称: | 2-hydroxy-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-2-methylpropanamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | McGowan, S.M, Drinkwater, N. | | 登録日 | 2023-04-24 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as a cross-species strategy to treat malaria
Elife, 2024
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8SLJ
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8SLI
 | | Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-1 | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 5 | | 著者 | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | 登録日 | 2023-04-21 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SLG
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8SLE
 | | Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-3 | | 分子名称: | Transient receptor potential cation channel subfamily M member 5 | | 著者 | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | 登録日 | 2023-04-21 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SLC
 | | High Affinity nanobodies against GFP | | 分子名称: | CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... | | 著者 | Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C. | | 登録日 | 2023-04-21 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | High Affinity nanobodies against GFP
To Be Published
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8SLB
 | | X-ray structure of CorA N-terminal domain in complex with conformation-specific synthetic antibody C12 | | 分子名称: | CHLORIDE ION, Cobalt/magnesium transport protein CorA, sAB C12 Heavy Chain, ... | | 著者 | Dominik, P.K, Erramilli, S.K, Reddy, B.G, Kossiakoff, A.A. | | 登録日 | 2023-04-21 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
J.Mol.Biol., 435, 2023
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8SLA
 | | Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-2 | | 分子名称: | Transient receptor potential cation channel subfamily M member 5 | | 著者 | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | 登録日 | 2023-04-21 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL8
 | | Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-1 | | 分子名称: | Transient receptor potential cation channel subfamily M member 5 | | 著者 | Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L. | | 登録日 | 2023-04-21 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL7
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8SL6
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8SL0
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8SKN
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8SKM
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8SKJ
 | | Crystal structure of a Nanobody bound to the V5 peptide. | | 分子名称: | NbA1, V5 Epitope Tag Peptide | | 著者 | Zaghal, M, Matte, K, Venes, A, Patel, S, Laroche, G, Sarvan, S, Joshi, M, Couture, J.F, Giguere, P.M. | | 登録日 | 2023-04-19 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signaling.
J.Biol.Chem., 299, 2023
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8SKH
 | | Co-structure of SARS-CoV-2 (COVID-19 with covalent pyrazoline based inhibitors | | 分子名称: | 2-chloro-1-[(4R,5R)-3,4,5-triphenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase nsp5 | | 著者 | Knapp, M.S, Ornelas, E. | | 登録日 | 2023-04-19 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (1.882 Å) | | 主引用文献 | Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors.
Chembiochem, 24, 2023
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8SKF
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8SK5
 | | Crystal structure of the SARS-CoV-2 neutralizing VHH 7A9 bound to the spike receptor binding domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, anti-SARS-CoV-2 receptor binding domain VHH | | 著者 | Noland, C.L, Pande, K, Zhang, L, Zhou, H, Galli, J, Eddins, M, Gomez-Llorente, Y. | | 登録日 | 2023-04-18 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | | 主引用文献 | Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.
Sci Rep, 13, 2023
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8SK4
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8SK0
 | | Crystal structure of EvdS6 decarboxylase in ligand bound state | | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Sharma, P, Frigo, L, Dulin, C.C, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2023-04-18 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | EvdS6 is a bifunctional decarboxylase from the everninomicin gene cluster.
J.Biol.Chem., 299, 2023
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8SJK
 | | Pembrolizumab Caffeine crystal | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY HEAVY CHAIN, ANTIBODY LIGHT CHAIN, ... | | 著者 | Larpent, P, Codan, L, Bothe, J.R, Stueber, D, Reichert, P, Fischmann, T, Su, Y, Pabit, S, Gupta, S, Iuzzolino, L, Cote, A. | | 登録日 | 2023-04-18 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Smaall angle X-ray scattering as powerful toolsfor phase and crystallinity assessment of monoclonal antibodies crystallites in support of batch crystallization and processing
To Be Published
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