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8G6R
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Porcine epidemic diarrhea virus core polymerase complex
分子名称: RNA (5'-R(P*AP*AP*GP*AP*AP*GP*CP*UP*AP*UP*UP*AP*AP*AP*AP*UP*CP*AP*CP*A)-3'), RNA (5'-R(P*GP*GP*UP*UP*GP*UP*GP*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*U)-3'), ZINC ION, ...
著者Anderson, T.K, Kirchdoerfer, R.N.
登録日2023-02-15
公開日2023-03-29
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Biorxiv, 2023
8CI5
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Structure of the SNV L protein bound to 5' RNA
分子名称: RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L
著者Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-02-08
公開日2023-07-19
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional characterization of the Sin Nombre virus L protein.
Plos Pathog., 19, 2023
8CEN
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Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Schilbach, S, Cramer, P.
登録日2023-02-02
公開日2023-03-22
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Cramer, P.
登録日2023-02-02
公開日2023-03-08
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FWL
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Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone
分子名称: DI(HYDROXYETHYL)ETHER, Phosphoprotein,Nucleoprotein
著者Donnelly, C.M, Stewart, M, Forwood, J.K.
登録日2023-01-23
公開日2023-03-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex.
Viruses, 16, 2023
8FUQ
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Crystal structure of rabies virus (strain CVS-11) P3 dimerization domain
分子名称: Phosphoprotein
著者Donnelly, C.M, Cross, E.M, Forwood, J.K.
登録日2023-01-18
公開日2023-01-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of rabies virus (strain CVS-11) P3 dimerization domain
To Be Published
8FU3
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Structure Of Respiratory Syncytial Virus Polymerase with Novel Non-Nucleoside Inhibitor
分子名称: 8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L
著者Yu, X, Abeywickrema, P, Bonneux, B, Behera, I, Jacoby, E, Fung, A, Adhikary, S, Bhaumik, A, Carbajo, R.J, Bruyn, S.D, Miller, R, Patrick, A, Pham, Q, Piassek, M, Verheyen, N, Shareef, A, Sutto-Ortiz, P, Ysebaert, N, Vlijmen, H.V, Jonckers, T.H.M, Herschke, F, McLellan, J.S, Decroly, E, Fearns, R, Grosse, S, Roymans, D, Sharma, S, Rigaux, P, Jin, Z.
登録日2023-01-16
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.
Commun Biol, 6, 2023
8C4T
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Hantaan virus polymerase bound to its 5' viral RNA
分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4U
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Hantaan virus polymerase in replication pre-initiation state
分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*GP*CP*GP*GP*AP*GP*UP*AP*CP*UP*AP*CP*UP*A)-3'), ...
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4S
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Apo Hantaan virus polymerase core
分子名称: RNA-directed RNA polymerase L
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4V
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BU of 8c4v by Molmil
Hantaan virus polymerase in replication elongation state
分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*CP*UP*AP*CP*UP*A)-3'), RNA (5'-R(P*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), ...
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8FPJ
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BU of 8fpj by Molmil
Co-structure of the Human Metapneunomovirus RNA-dependent RNA polymerase with MRK-1
分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L
著者Fischmann, T.O.
登録日2023-01-04
公開日2023-06-14
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.
Commun Biol, 6, 2023
8FPI
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Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1
分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L
著者Fischmann, T.O.
登録日2023-01-04
公開日2023-06-14
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.
Commun Biol, 6, 2023
8FM9
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BU of 8fm9 by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FMB
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Nodavirus RNA replication protein A polymerase domain, local refinement
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FMA
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BU of 8fma by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8C2P
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BU of 8c2p by Molmil
FMDV 3D polymerase in complex with 3B3
分子名称: Protein 3B-3, RNA-directed RNA polymerase 3D-POL
著者Ferrer-Orta, C, Veraguer, N.
登録日2022-12-22
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Plos Pathog., 19, 2023
8C1N
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BU of 8c1n by Molmil
FMDV 3D polymerase in complex with 3B1 protein solved in P212121 space group
分子名称: ACETATE ION, GLYCEROL, Protein 3B-1, ...
著者Ferrer-Orta, C, Veraguer, N.
登録日2022-12-20
公開日2023-04-26
最終更新日2023-05-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Plos Pathog., 19, 2023
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-20
公開日2023-05-03
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8FJL
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Golden Shiner Reovirus Core Tropical Vertex
分子名称: Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ...
著者Stevens, A.S, Zhou, Z.H.
登録日2022-12-19
公開日2023-03-08
最終更新日2023-07-12
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
Protein Cell, 14, 2023
8FJK
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Golden Shiner Reovirus Core Polar Vertex
分子名称: Clamp protein VP6, Major inner capsid protein VP3, Microtubule-associated protein VP5, ...
著者Stevens, A.S, Zhou, Z.H.
登録日2022-12-19
公開日2023-03-22
最終更新日2023-07-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation.
Protein Cell, 14, 2023
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-14
公開日2023-05-03
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BZ1
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RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-14
公開日2023-05-03
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BWS
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Structure of yeast RNA Polymerase III elongation complex at 3.3 A
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-12-07
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
8HE5
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RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome
分子名称: DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ...
著者Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H.
登録日2022-11-07
公開日2023-07-05
実験手法ELECTRON MICROSCOPY (6.95 Å)
主引用文献Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023

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件を2024-06-12に公開中

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