PDB: 317 件ウェブページステータス検索Chemie searchBIRD

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6FI7	E.coli Sigma factor S (RpoS) Region 4 分子名称: RNA polymerase sigma factor RpoS 著者 Liu, B, Matthews, S.J. 登録日 2018-01-17 公開日 2018-06-06 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 T7 phage factor required for managing RpoS inEscherichia coli. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CA0	Cryo-EM structure of E. coli RNAP sigma70 open complex 分子名称: DNA (35-MER), DNA (45-MER), DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*CP*AP*GP*A)-3'), ... 著者 Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yernool, D, Jiang, W, Murakami, K.S. 登録日 2018-01-29 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.75 Å) 主引用文献 Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
6C9Y	Cryo-EM structure of E. coli RNAP sigma70 holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S. 登録日 2018-01-29 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.25 Å) 主引用文献 Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
6CCE	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A 分子名称: 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2018-02-07 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
6CCV	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2018-02-07 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
6CUX	Escherichia coli RpoB S531L mutant RNA polymerase holoenzyme in complex with Kanglemycin A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-03-26 公開日 2018-07-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (4.104 Å) 主引用文献 Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
6CUU	Thermus thermophiles RNA polymerase in complex with promoter DNA and antibiotic Kanglemycin A 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*A)-3'), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-03-26 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.994 Å) 主引用文献 Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
6DCF	Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase and bound to kanglemycin A 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2018-05-06 公開日 2018-09-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
6DVB	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6DV9	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6DVC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6DVE	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*GP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2019-02-27 実験手法 X-RAY DIFFRACTION (3.812 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6DVD	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.899 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6EDT	Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter 分子名称: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-10 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6EEC	Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin 分子名称: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-13 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6EE8	Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter 分子名称: DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-13 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.92 Å) 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6M7J	Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin 分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-20 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6IDO	Crystal structure of Klebsiella pneumoniae sigma4 of sigmaS fusing with the RNA polymerase beta-flap-tip-helix in complex with -35 element DNA 分子名称: DNA (5'-D(P*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*AP*AP*TP*CP*G)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*C)-3'), RNA polymerase sigma factor RpoS,RNA polymerase beta-flap-tip-helix 著者 Lou, Y.C, Chien, C.Y, Chen, C, Hsu, C.H. 登録日 2018-09-10 公開日 2019-09-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.748 Å) 主引用文献 Structural basis for -35 element recognition by sigma4chimera proteins and their interactions with PmrA response regulator. Proteins, 88, 2020
6N4C	EM structure of the DNA wrapping in bacterial open transcription initiation complex 分子名称: DNA (94-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Florez-Ariza, A, Cassago, A, de Oliveira, P.S.L, Guerra, D.G, Portugal, R.V. 登録日 2018-11-19 公開日 2020-05-27 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation Biorxiv, 2020
6N57	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6N58	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6N60	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-23 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N62	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.803 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N61	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.253 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6JNX	Cryo-EM structure of a Q-engaged arrested complex 分子名称: Antiterminator Q protein, DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Feng, Y, Shi, J. 登録日 2019-03-18 公開日 2019-06-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.08 Å) 主引用文献 Structural basis of Q-dependent transcription antitermination. Nat Commun, 10, 2019

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