PDB: 286 件ウェブページステータス検索Chemie searchBIRD

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2YVX	Crystal structure of magnesium transporter MgtE 分子名称: MAGNESIUM ION, Mg2+ transporter MgtE 著者 Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O. 登録日 2007-04-18 公開日 2007-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the MgtE Mg(2+) transporter Nature, 448, 2007
3TDH	Structure of the regulatory fragment of sccharomyces cerevisiae AMPK in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... 著者 Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D. 登録日 2011-08-11 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
4EAI	Co-crystal structure of an AMPK core with AMP 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.285 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAK	Co-crystal structure of an AMPK core with ATP 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAJ	Co-crystal of AMPK core with AMP soaked with ATP 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.609 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAG	Co-crystal structure of an chimeric AMPK core with ATP 分子名称: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4EAL	Co-crystal of AMPK core with ATP soaked with AMP 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.506 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
2OUX	Crystal structure of the soluble part of a magnesium transporter 分子名称: MAGNESIUM ION, Magnesium transporter 著者 Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-02-12 公開日 2007-03-20 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Structural studies on cytosolic domain of magnesium transporter MgtE from Enterococcus faecalis. Proteins, 78, 2010
2OOX	Crystal structure of the adenylate sensor from AMP-activated protein kinase complexed with AMP 分子名称: ADENOSINE MONOPHOSPHATE, Hypothetical protein C1556.08c in chromosome I, SNF1-like protein kinase ssp2, ... 著者 Townley, R, Shapiro, L. 登録日 2007-01-26 公開日 2007-02-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science, 315, 2007
2OOY	Crystal structure of the adenylate sensor from AMP-activated protein kinase complexed with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CITRATE ANION, Hypothetical protein C1556.08c in chromosome I, ... 著者 Townley, R, Shapiro, L. 登録日 2007-01-26 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science, 315, 2007
2QRD	Crystal Structure of the Adenylate Sensor from AMP-activated Protein Kinase in complex with ADP and ATP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Protein C1556.08c, ... 著者 Jin, X, Townley, R, Shapiro, L. 登録日 2007-07-28 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
2QH1	Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state 分子名称: FE (II) ION, Hypothetical protein Ta0289 著者 Singer, A.U, Proudfoot, M, Brown, G, Xu, L, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) 登録日 2007-06-29 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J.Mol.Biol., 375, 2008
2QRE	Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranotide (ZMP) 分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Protein C1556.08c, SNF1-like protein kinase ssp2, ... 著者 Jin, X, Townley, R, Shapiro, L. 登録日 2007-07-28 公開日 2007-10-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
2QLV	Crystal structure of the heterotrimer core of the S. cerevisiae AMPK homolog SNF1 分子名称: Carbon catabolite derepressing protein kinase, Nuclear protein SNF4, Protein SIP2 著者 Amodeo, G.A, Rudolph, M.J, Tong, L. 登録日 2007-07-13 公開日 2007-09-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1. Nature, 449, 2007
2QR1	Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Protein C1556.08c, SNF1-like protein kinase ssp2, ... 著者 Jin, X, Townley, R, Shapiro, L. 登録日 2007-07-27 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
6XWL	Cystathionine beta-synthase from Toxoplasma gondii 分子名称: Cystathionine beta-synthase, PYRIDOXAL-5'-PHOSPHATE 著者 Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A. 登録日 2020-01-23 公開日 2021-02-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii . Comput Struct Biotechnol J, 19, 2021
5EZV	X-ray crystal structure of AMP-activated protein kinase alpha-2/alpha-1 RIM chimaera (alpha-2(1-347)/alpha-1(349-401)/alpha-2(397-end) beta-1 gamma-1) co-crystallized with C2 (5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid) 分子名称: 3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-2/alpha-1 RIM SWAP chimera, 5'-AMP-activated protein kinase subunit beta-1, ... 著者 Langendorf, C.G, Kemp, B.E. 登録日 2015-11-26 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding. Nat Commun, 7, 2016
8CGY	Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... 著者 Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Duden, R, Bourenkov, G, Schneider, T, Redecke, L. 登録日 2023-02-06 公開日 2024-02-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
1ME9	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, POTASSIUM ION 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1MEW	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
7OJ1	Bacillus subtilis IMPDH in complex with Ap4A 分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION 著者 Giammarinaro, P.I, Bange, G. 登録日 2021-05-13 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
5TSR	Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter 分子名称: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 3 著者 Kozlov, G, Zhang, H, Gehring, K. 登録日 2016-10-31 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.188 Å) 主引用文献 PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3. Sci Rep, 7, 2017
5UFU	Structure of AMPK bound to activator 分子名称: 1,4:3,6-dianhydro-2-O-(6-chloro-5-{4-[1-(hydroxymethyl)cyclopropyl]phenyl}-1H-benzimidazol-2-yl)-D-mannitol, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... 著者 Calabrese, M.F, Kurumbail, R.G. 登録日 2017-01-05 公開日 2017-05-17 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. Cell Metab., 25, 2017
7OY9	Crystal structure of GMP reductase from mycobacterium smegmatis. 分子名称: Guanosine 5'-monophosphate reductase 著者 Dolezal, M, Klima, M, Pichova, I. 登録日 2021-06-24 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-beta-synthase domain. Febs J., 289, 2022
1B3O	TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE 分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), ... 著者 Colby, T.D, Vanderveen, K, Strickler, M.D, Goldstein, B.M. 登録日 1998-12-14 公開日 1999-04-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proc.Natl.Acad.Sci.USA, 96, 1999

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