PDB: 594 件ウェブページステータス検索Chemie searchBIRD

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1SHA	CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES 分子名称: PHOSPHOPEPTIDE A, V-SRC SH2 DOMAIN 著者 Waksman, G, Kuriyan, J. 登録日 1992-08-18 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature, 358, 1992
3US4	Crystal structure of a SH2 domain of a megakaryocyte-associated tyrosine kinase (MATK) from Homo sapiens at 1.50 A resolution 分子名称: Megakaryocyte-associated tyrosine-protein kinase, SULFATE ION 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-11-22 公開日 2011-12-28 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a SH2 domain of a megakaryocyte-associated tyrosine kinase (MATK) from Homo sapiens at 1.50 A resolution To be published
3PQZ	Grb7 SH2 with peptide 分子名称: Growth factor receptor-bound protein 7, cyclic peptide 著者 Wilce, J.A. 登録日 2010-11-29 公開日 2011-07-20 最終更新日 2011-09-21 実験手法 X-RAY DIFFRACTION (2.413 Å) 主引用文献 Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression J.Mol.Biol., 412, 2011
4K44	Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 著者 Hajicek, N, Sondek, J. 登録日 2013-04-11 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes. Biochemistry, 52, 2013
1RJA	Solution Structure and Backbone Dynamics of the Nonreceptor Tyrosine Kinase PTK6/Brk SH2 Domain 分子名称: Tyrosine-protein kinase 6 著者 Hong, E, Shin, J, Lee, W. 登録日 2003-11-18 公開日 2004-07-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Backbone Dynamics of the Non-receptor Protein-tyrosine Kinase-6 Src Homology 2 Domain J.Biol.Chem., 279, 2004
1R1P	Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads 分子名称: GRB2-related adaptor protein 2, LAT pY171 peptide, SULFATE ION 著者 Cho, S, Mariuzza, R.A. 登録日 2003-09-24 公開日 2004-09-28 最終更新日 2020-01-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads. Embo J., 23, 2004
3S8N	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide 分子名称: CHLORIDE ION, GLYCEROL, Growth factor receptor-bound protein 2, ... 著者 Clements, J.H, Stephen, F.M. 登録日 2011-05-29 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
1SHB	CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES 分子名称: PHOSPHOPEPTIDE B, V-SRC SH2 DOMAIN 著者 Waksman, G, Kuriyan, J. 登録日 1992-08-18 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature, 358, 1992
3UYO	Crystal structure of monobody SH13/ABL1 SH2 domain complex 分子名称: Monobody SH13, SULFATE ION, Tyrosine-protein kinase ABL1 著者 Wojcik, J.B, Koide, A, Koide, S. 登録日 2011-12-06 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold. J.Mol.Biol., 415, 2012
3PSJ	Crystal Structure of the Spt6 Tandem SH2 Domain from Saccharomyces cerevisiae, Form Se-Spt6 (1247-1451) 分子名称: SULFATE ION, Transcription elongation factor SPT6 著者 Close, D, Hill, C.P. 登録日 2010-12-01 公開日 2011-03-30 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
4K45	Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, short peptide 著者 Sondek, J, Hajicek, N. 登録日 2013-04-11 公開日 2013-06-26 最終更新日 2014-01-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes. Biochemistry, 52, 2013
1RPY	CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS 分子名称: SULFATE ION, adaptor protein APS 著者 Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R. 登録日 2003-12-03 公開日 2003-12-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol.Cell, 12, 2003
1SHD	PEPTIDE INHIBITORS OF SRC SH3-SH2-PHOSPHOPROTEIN INTERACTIONS 分子名称: C-SRC TYROSINE KINASE SH2 DOMAIN, TRKA RECEPTOR 著者 Gilmer, T, Jordan, S. 登録日 1994-11-10 公開日 1995-01-26 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Peptide inhibitors of src SH3-SH2-phosphoprotein interactions. J.Biol.Chem., 269, 1994
1TZE	SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2) 分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 著者 Rahuel, J, Grutter, M.G. 登録日 1996-06-06 公開日 1997-07-07 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode. Nat.Struct.Biol., 3, 1996
3PSK	Crystal Structure of the Spt6 Tandem SH2 Domain from Saccharomyces cerevisiae, Form Native Spt6 (1247-1451) 分子名称: SULFATE ION, Transcription elongation factor SPT6 著者 Close, D, Hill, C.P. 登録日 2010-12-01 公開日 2011-03-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
3T04	Crystal structure of monobody 7c12/abl1 sh2 domain complex 分子名称: GLYCEROL, MONOBODY 7C12, SULFATE ION, ... 著者 Wojcik, J.B, Wyrzucki, A.M, Koide, S. 登録日 2011-07-19 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis. Cell(Cambridge,Mass.), 147, 2011
3WA4	Grb2 SH2 domain/CD28-derived peptide complex 分子名称: ACETIC ACID, CADMIUM ION, Growth factor receptor-bound protein 2, ... 著者 Higo, K, Oda, M, Ito, N. 登録日 2013-04-23 公開日 2014-02-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 High Resolution Crystal Structure of the Grb2 SH2 Domain with a Phosphopeptide Derived from CD28 Plos One, 8, 2013
3S9K	Crystal structure of the Itk SH2 domain. 分子名称: CITRIC ACID, Tyrosine-protein kinase ITK/TSK 著者 Joseph, R.E, Ginder, N.D, Hoy, J.A, Nix, J.C, Fulton, B.D, Honzatko, R.B, Andreotti, A.H. 登録日 2011-06-01 公開日 2012-02-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.354 Å) 主引用文献 Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures. Acta Crystallogr.,Sect.F, 68, 2012
3S8L	Protein-Ligand Interactions: Thermodynamic Effects Associated with Increasing Hydrophobic Surface Area 分子名称: CHLORIDE ION, GLYCEROL, Growth factor receptor-bound protein 2, ... 著者 Clements, J.H, Stephen, F.M. 登録日 2011-05-29 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
3S8O	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide 分子名称: CHLORIDE ION, Growth factor receptor-bound protein 2, SODIUM ION, ... 著者 Clements, J.H, Stephen, F.M. 登録日 2011-05-29 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
3TKZ	Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide 分子名称: PROTEIN (RVIpYFVPLNR peptide), Tyrosine-protein phosphatase non-receptor type 11 著者 Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. 登録日 2011-08-29 公開日 2011-10-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
3TL0	Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide 分子名称: RLNpYAQLWHR peptide, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 著者 Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. 登録日 2011-08-29 公開日 2011-09-28 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
2L6K	Solution Structure of a Nonphosphorylated Peptide Recognizing Domain 分子名称: Tensin-like C1 domain-containing phosphatase 著者 Dai, K, Liao, S, Zhang, J, Zhang, X, Tu, X. 登録日 2010-11-22 公開日 2011-10-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of Tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1 Plos One, 6, 2011
2LNW	Identification and structural basis for a novel interaction between Vav2 and Arap3 分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
2LCT	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Gorenstein, N, Post, C. 登録日 2011-05-09 公開日 2011-06-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. Mol.Cell.Biol., 31, 2011

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