PDB: 140 件ウェブページステータス検索Chemie searchBIRD

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4IM2	Structure of Tank-Binding Kinase 1 分子名称: CHLORIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1 著者 Tu, D, Eck, M.J. 登録日 2013-01-01 公開日 2013-03-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5001 Å) 主引用文献 Structure and ubiquitination-dependent activation of TANK-binding kinase 1. Cell Rep, 3, 2013
4IM0	Structure of Tank-Binding Kinase 1 分子名称: N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, Serine/threonine-protein kinase TBK1 著者 Tu, D, Eck, M.J. 登録日 2013-01-01 公開日 2013-03-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4001 Å) 主引用文献 Structure and ubiquitination-dependent activation of TANK-binding kinase 1. Cell Rep, 3, 2013
4KSY	Crystal structure of STING in complex with cGAMP 分子名称: Stimulator of interferon genes protein, cGAMP 著者 Zhang, X, Chen, Z.J, Zhang, X.W. 登録日 2013-05-18 公開日 2013-06-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.881 Å) 主引用文献 Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING. Mol.Cell, 51, 2013
4KBY	mSTING/c-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Stimulator of interferon genes protein 著者 Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H. 登録日 2013-04-24 公開日 2013-05-29 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING Acta Crystallogr.,Sect.D, 69, 2013
4KC0	mSTING 分子名称: Stimulator of interferon genes protein 著者 Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H. 登録日 2013-04-24 公開日 2013-05-29 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING Acta Crystallogr.,Sect.D, 69, 2013
4EFO	Crystal structure of the ubiquitin-like domain of human TBK1 分子名称: Serine/threonine-protein kinase TBK1 著者 Li, J, Li, J, Miyahira, A, Sun, J, Liu, Y, Cheng, G, Liang, H. 登録日 2012-03-30 公開日 2012-06-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.769 Å) 主引用文献 Crystal structure of the ubiquitin-like domain of human TBK1. Protein Cell, 3, 2012
4EMT	Crystal Structure of human STING bound to c-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 著者 Li, P. 登録日 2012-04-12 公開日 2012-06-13 最終更新日 2012-07-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19, 2012
4F5D	ERIS/STING in complex with ligand 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Transmembrane protein 173 著者 Huang, Y.H, Liu, X.Y, Su, X.D. 登録日 2012-05-13 公開日 2012-06-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19, 2012
4F9G	Crystal structure of STING complex with Cyclic di-GMP. 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Transmembrane protein 173 著者 Kabaleeswaran, V, Wu, H. 登録日 2012-05-18 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING. Mol.Cell, 46, 2012
4F5Y	Crystal structure of human STING CTD complex with C-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 著者 Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. 登録日 2012-05-13 公開日 2012-06-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.396 Å) 主引用文献 Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP Nat.Struct.Mol.Biol., 19, 2012
4F5W	Crystal structure of ligand free human STING CTD 分子名称: CALCIUM ION, Transmembrane protein 173 著者 Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. 登録日 2012-05-13 公開日 2012-06-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP Nat.Struct.Mol.Biol., 19, 2012
4F9E	Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING 分子名称: Transmembrane protein 173 著者 Kabaleeswaran, V, Wu, H. 登録日 2012-05-18 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING. Mol.Cell, 46, 2012
4F5E	Crystal structure of ERIS/STING 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Transmembrane protein 173 著者 Huang, Y.H, Liu, X.Y, Su, X.D. 登録日 2012-05-13 公開日 2012-06-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19, 2012
4EMU	Crystal structure of ligand free human STING 分子名称: CALCIUM ION, Transmembrane protein 173 著者 Li, P. 登録日 2012-04-12 公開日 2012-06-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19, 2012
4GHL	Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ramanan, P, Borek, D.M, Otwinowski, Z, Leung, D.W, Amarasinghe, G.K. 登録日 2012-08-07 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proc.Natl.Acad.Sci.USA, 109, 2012

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