7AA4
 
 | Structure of ClpC1-NTD bound to a CymA analogue | 分子名称: | Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue | 著者 | Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. | 登録日 | 2020-09-03 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
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3TV6
 
 | Human B-Raf Kinase Domain in Complex with a Methoxypyrazolopyridinyl Benzamide Inhibitor | 分子名称: | 2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide, Serine/threonine-protein kinase B-raf | 著者 | Voegtli, W.C, Sturgis, H.L, Wu, W.-I. | 登録日 | 2011-09-19 | 公開日 | 2011-10-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors. ACS Med Chem Lett, 2, 2011
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1E0E
 
 | N-terminal zinc-binding HHCC domain of HIV-2 integrase | 分子名称: | HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 INTEGRASE, ZINC ION | 著者 | Eijkelenboom, A.P.A.M, Van Den ent, F.M.I, Plasterk, R.H.A, Kaptein, R, Boelens, R. | 登録日 | 2000-03-25 | 公開日 | 2001-03-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Refined Solution Structure of the Dimeric N-Terminal Hhcc Domain of HIV-2 Integrase J.Biomol.NMR, 18, 2000
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3FD7
 
 | Crystal structure of Onconase C87A/C104A-ONC | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein P-30, ... | 著者 | Neumann, P, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Stubbs, M.T. | 登録日 | 2008-11-25 | 公開日 | 2009-12-08 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.531 Å) | 主引用文献 | Impact of the C-terminal disulfide bond on the folding and stability of onconase. Chembiochem, 11, 2010
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9ATV
 
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9ARJ
 
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9ARK
 
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9ARL
 
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7Y43
 
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4EIG
 
 | CA1698 camel antibody fragment in complex with DHFR | 分子名称: | CA1698 camel antibody fragment, Dihydrofolate reductase | 著者 | Oyen, D, Srinivasan, V. | 登録日 | 2012-04-05 | 公開日 | 2013-04-24 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
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4EIZ
 
 | Structure of Nb113 bound to apoDHFR | 分子名称: | Dihydrofolate reductase, Nb113 Camel antibody fragment | 著者 | Oyen, D, Srinivasan, V. | 登録日 | 2012-04-06 | 公開日 | 2013-04-24 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
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5O8D
 
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4EJ1
 
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1O58
 
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4FGV
 
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1O2D
 
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4FHB
 
 | Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Oyen, D. | 登録日 | 2012-06-06 | 公開日 | 2013-04-24 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
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5O9Z
 
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5O86
 
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2KB6
 
 | Solution structure of onconase C87A/C104A | 分子名称: | Protein P-30 | 著者 | Weininger, U, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Balbach, J. | 登録日 | 2008-11-21 | 公開日 | 2009-11-24 | 最終更新日 | 2024-10-30 | 実験手法 | SOLUTION NMR | 主引用文献 | Impact of the C-terminal disulfide bond on the folding and stability of onconase. Chembiochem, 11, 2010
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2LFJ
 
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7BL6
 
 | 50S-ObgE-GMPPNP particle | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | 登録日 | 2021-01-18 | 公開日 | 2021-05-12 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL2
 
 | pre-50S-ObgE particle state 1 | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | 著者 | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | 登録日 | 2021-01-18 | 公開日 | 2021-05-12 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL3
 
 | pre-50S-ObgE particle state 2 | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T. | 登録日 | 2021-01-18 | 公開日 | 2021-05-12 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL5
 
 | pre-50S-ObgE particle | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T, Schmidt, S. | 登録日 | 2021-01-18 | 公開日 | 2021-05-12 | 最終更新日 | 2025-04-09 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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