1FA6
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![BU of 1fa6 by Molmil](/molmil-images/mine/1fa6) | CRYSTAL STRUCTURE OF THE CO(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI | 分子名称: | COBALT (II) ION, GLYOXALASE I | 著者 | He, M.M, Clugston, S.L, Honek, J.F, Matthews, B.W. | 登録日 | 2000-07-12 | 公開日 | 2000-09-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation. Biochemistry, 39, 2000
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3TTJ
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![BU of 3ttj by Molmil](/molmil-images/mine/3ttj) | Crystal Structure of JNK3 complexed with CC-359, a JNK inhibitor for the prevention of ischemia-reperfusion injury | 分子名称: | 9-cyclopentyl-N~8~-(2-fluorophenyl)-N~2~-(4-methoxyphenyl)-9H-purine-2,8-diamine, Mitogen-activated protein kinase 10 | 著者 | Plantevin-Krenitsky, V, Delgado, M, Nadolny, L, Sahasrabudhe, K, Ayala, S, Clareen, S, Hilgraf, R, Albers, R, Kois, A, Hughes, K, Wright, J, Nowakowski, J, Sudbeck, E, Ghosh, S, Bahmanyar, S, Chamberlain, P, Muir, J, Cathers, B.E, Giegel, D, Xu, L, Celeridad, M, Moghaddam, M, Khatsenko, O, Omholt, P, Katz, J, Pai, S, Fan, R, Tang, Y, Shirley, M.A, Benish, B, Blease, K, Raymon, H, Bhagwat, S, Bennett, B, Satoh, Y. | 登録日 | 2011-09-14 | 公開日 | 2012-01-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury. Bioorg.Med.Chem.Lett., 22, 2012
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3U1P
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![BU of 3u1p by Molmil](/molmil-images/mine/3u1p) | Crystal Structure of M. tuberculosis LD-transpeptidase type 2 with Modified Catalytic Cysteine (C354) | 分子名称: | DI(HYDROXYETHYL)ETHER, Mycobacteria Tuberculosis LD-transpeptidase type 2 | 著者 | Erdemli, S, Bianchet, M.A, Gupta, R, Lamichhane, G, Amzel, L.M. | 登録日 | 2011-09-30 | 公開日 | 2012-12-05 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2. Structure, 20, 2012
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3QPP
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![BU of 3qpp by Molmil](/molmil-images/mine/3qpp) | Structure of PDE10-inhibitor complex | 分子名称: | 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Pandit, J, Marr, E.S. | 登録日 | 2011-02-14 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J.Med.Chem., 54, 2011
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1GT9
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![BU of 1gt9 by Molmil](/molmil-images/mine/1gt9) | High resolution crystal structure of a thermostable serine-carboxyl type proteinase, kumamolisin (kscp) | 分子名称: | CALCIUM ION, KUMAMOLYSIN, SULFATE ION | 著者 | Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W. | 登録日 | 2002-01-14 | 公開日 | 2002-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase Structure, 10, 2002
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3QPO
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![BU of 3qpo by Molmil](/molmil-images/mine/3qpo) | Structure of PDE10-inhibitor complex | 分子名称: | 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline, MAGNESIUM ION, SULFATE ION, ... | 著者 | Pandit, J, Marr, E.S. | 登録日 | 2011-02-14 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J.Med.Chem., 54, 2011
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1UXN
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![BU of 1uxn by Molmil](/molmil-images/mine/1uxn) | Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Lorentzen, E, Hensel, R, Pohl, E. | 登録日 | 2004-02-27 | 公開日 | 2004-08-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
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1UTJ
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![BU of 1utj by Molmil](/molmil-images/mine/1utj) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | 分子名称: | BENZYLAMINE, CALCIUM ION, TRYPSIN I | 著者 | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | 登録日 | 2003-12-09 | 公開日 | 2004-01-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1DJ5
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1DKA
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![BU of 1dka by Molmil](/molmil-images/mine/1dka) | DIALKYLGLYCINE DECARBOXYLASE STRUCTURE: BIFUNCTIONAL ACTIVE SITE AND ALKALI METAL BINDING SITES | 分子名称: | 2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, POTASSIUM ION, ... | 著者 | Toney, M.D, Hohenester, E, Jansonius, J.N. | 登録日 | 1993-06-18 | 公開日 | 1994-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites. Science, 261, 1993
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1DMK
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![BU of 1dmk by Molmil](/molmil-images/mine/1dmk) | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 4-AMINO-6-PHENYL-TETRAHYDROPTERIDINE | 分子名称: | 2,4-DIAMINO-6-PHENYL-5,6,7,8,-TETRAHYDROPTERIDINE, ACETATE ION, CACODYLATE ION, ... | 著者 | Kotsonis, P, Frohlich, L.G, Raman, C.S, Li, H, Berg, M, Gerwig, R, Groehn, V, Kang, Y, Al-Masoudi, N, Taghavi-Moghadam, S, Mohr, D, Munch, U, Schnabel, J, Martasek, P, Masters, B.S, Strobel, H, Poulos, T, Matter, H, Pfleiderer, W, Schmidt, H.H. | 登録日 | 1999-12-14 | 公開日 | 2000-12-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin J.Biol.Chem., 276, 2001
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1S9I
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![BU of 1s9i by Molmil](/molmil-images/mine/1s9i) | X-ray structure of the human mitogen-activated protein kinase kinase 2 (MEK2)in a complex with ligand and MgATP | 分子名称: | 5-{3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]PHENYL}-N-(2-MORPHOLIN-4-YLETHYL)-1,3,4-OXADIAZOL-2-AMINE, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 2, ... | 著者 | Ohren, J.F, Chen, H, Pavlovsky, A, Whitehead, C, Yan, C, McConnell, P, Delaney, A, Dudley, D.T, Sebolt-Leopold, J, Hasemann, C.A. | 登録日 | 2004-02-04 | 公開日 | 2004-11-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat.Struct.Mol.Biol., 11, 2004
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1DJ7
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![BU of 1dj7 by Molmil](/molmil-images/mine/1dj7) | CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE | 分子名称: | FERREDOXIN THIOREDOXIN REDUCTASE: CATALYTIC CHAIN, FERREDOXIN THIOREDOXIN REDUCTASE: VARIABLE CHAIN, IRON/SULFUR CLUSTER, ... | 著者 | Dai, S, Schwendtmayer, C, Schurmann, P, Ramaswamy, S, Eklund, H. | 登録日 | 1999-12-02 | 公開日 | 2000-02-14 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Redox signaling in chloroplasts: cleavage of disulfides by an iron-sulfur cluster. Science, 287, 2000
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1GTJ
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![BU of 1gtj by Molmil](/molmil-images/mine/1gtj) | Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolisin (KSCP) - complex with Ac-Ile-Ala-Phe-cho | 分子名称: | ALDEHYDE INHIBITOR, CALCIUM ION, KUMAMOLYSIN, ... | 著者 | Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W. | 登録日 | 2002-01-15 | 公開日 | 2002-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase Structure, 10, 2002
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1H0D
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![BU of 1h0d by Molmil](/molmil-images/mine/1h0d) | Crystal structure of Human Angiogenin in complex with Fab fragment of its monoclonal antibody mAb 26-2F | 分子名称: | ANGIOGENIN, ANTIBODY FAB FRAGMENT, HEAVY CHAIN, ... | 著者 | Chavali, G.B, Papageorgiou, A.C, Acharya, K.R. | 登録日 | 2002-06-19 | 公開日 | 2003-06-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of Human Angiogenin in Complex with an Antitumor Neutralizing Antibody Structure, 11, 2003
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1GTG
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![BU of 1gtg by Molmil](/molmil-images/mine/1gtg) | Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolysin (kscp) | 分子名称: | CALCIUM ION, KUMAMOLYSIN | 著者 | Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W. | 登録日 | 2002-01-15 | 公開日 | 2002-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase Structure, 10, 2002
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3TX4
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![BU of 3tx4 by Molmil](/molmil-images/mine/3tx4) | Crystal Structure of Mutant (C354A) M. tuberculosis LD-transpeptidase type 2 | 分子名称: | Mycobacterium Tuberculosis LD-transpeptidase type 2 | 著者 | Erdemli, S, Bianchet, M.A, Gupta, R, Lamichhane, G, Amzel, L.M. | 登録日 | 2011-09-22 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2. Structure, 20, 2012
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7OVO
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![BU of 7ovo by Molmil](/molmil-images/mine/7ovo) | Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine | 分子名称: | 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Queuine tRNA-ribosyltransferase accessory subunit 2, ... | 著者 | Sebastiani, M, Heine, A, Reuter, K. | 登録日 | 2021-06-15 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
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7OV9
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![BU of 7ov9 by Molmil](/molmil-images/mine/7ov9) | Heterodimeric tRNA-Guanine Transglycosylase from mouse, apo-structure | 分子名称: | HEXAETHYLENE GLYCOL, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ... | 著者 | Sebastiani, M, Heine, A, Reuter, K. | 登録日 | 2021-06-14 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
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7OVS
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![BU of 7ovs by Molmil](/molmil-images/mine/7ovs) | Heterodimeric murine tRNA-guanine transglycosylase in the presence of Anderson-Evans type (TEW) and Strandberg type polyoxometalate (POM) | 分子名称: | 6-tungstotellurate(VI), Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ... | 著者 | Sebastiani, M, Heine, A, Reuter, K. | 登録日 | 2021-06-15 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
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1X06
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![BU of 1x06 by Molmil](/molmil-images/mine/1x06) | Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg, IPP and Fspp | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | 著者 | Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H. | 登録日 | 2005-03-15 | 公開日 | 2005-03-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. J.Biol.Chem., 280, 2005
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1WCI
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![BU of 1wci by Molmil](/molmil-images/mine/1wci) | Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-BUTYL-THIAMIN, ... | 著者 | Machius, M, Wynn, R.M, Chuang, J.L, Tomchick, D.R, Brautigam, C.A, Chuang, D.T. | 登録日 | 2004-11-16 | 公開日 | 2006-02-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure, 14, 2006
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7SL6
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7SL7
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7SL2
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