PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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4DJU	Structure of BACE Bound to 2-imino-3-methyl-5,5-diphenylimidazolidin-4-one 分子名称: (2E)-2-imino-3-methyl-5,5-diphenylimidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Strickland, C, Cumming, J. 登録日 2012-02-02 公開日 2012-03-21 最終更新日 2012-04-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
6GEO	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 10j 分子名称: 2-chloranyl-3-[4-(imidazol-1-ylmethyl)-1-phenyl-pyrazol-3-yl]-1~{H}-indole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C.W. 登録日 2018-04-27 公開日 2019-08-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
6GC5	Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM 分子名称: AU-rich RNA, ELAV-like protein 1 著者 Ripin, N, Allain, F.H. 登録日 2018-04-17 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4DLV	H-Ras Set 2 CaCl2/DTT, ordered off 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.572 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
6GD6	Cytochrome c in complex with Sulfonato-calix[8]arene, H3 form with ammonium sulfate 分子名称: Cytochrome c iso-1, HEME C, SULFATE ION, ... 著者 Rennie, M.L, Fox, G.C, Crowley, P.B. 登録日 2018-04-23 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Auto-regulated Protein Assembly on a Supramolecular Scaffold. Angew. Chem. Int. Ed. Engl., 57, 2018
4DX1	Crystal structure of the human TRPV4 ankyrin repeat domain 分子名称: GLYCEROL, PHOSPHATE ION, Transient receptor potential cation channel subfamily V member 4 著者 Inada, H, Gaudet, R. 登録日 2012-02-27 公開日 2012-07-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry, 51, 2012
6GEQ	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 14a 分子名称: 1-phenyl-3-pyridin-4-yl-~{N}-(pyridin-4-ylmethyl)pyrazole-4-carboxamide, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C.W. 登録日 2018-04-27 公開日 2019-08-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
3MFJ	Bovine trypsin at 0.8 A resolution, restrained refinement 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Brzuszkiewicz, A, Dauter, M, Dauter, Z. 登録日 2010-04-02 公開日 2010-04-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (0.8 Å) 主引用文献 Bovine trypsin at 0.8 A and role of restraints at ultra-high resolution To be Published
4DUC	cytochrome P450 BM3h-2G9 MRI sensor, no ligand 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 2G9 著者 Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. 登録日 2012-02-21 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
3M7T	Crystal Structure of Alpha-Lytic Protease SB2+3 E8A/R105S Mutant 分子名称: Alpha-lytic protease, GLYCEROL, SULFATE ION 著者 Agard, D.A, Erciyas Bailey, F.P, Waddling, C.A. 登録日 2010-03-17 公開日 2011-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Quantifying protein unfolding cooperativity with acid sensitive probes: Interdomain salt bridge contributions to unfolding cooperativity are combined efficiently in alpha-Lytic Protease To be Published
6FVC	Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants 分子名称: Segmentation polarity homeobox protein engrailed 著者 Trosanova, Z, Zachrdla, M, Jansen, S, Srb, P, Zidek, L, Kozelka, J. 登録日 2018-03-02 公開日 2019-04-03 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants. Phys Chem Chem Phys, 20, 2018
7DVO	Structure of Reaction Intermediate of Cytochrome P450 NO Reductase (P450nor) Determined by XFEL 分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ... 著者 Nomura, T, Kimura, T, Kanematsu, Y, Yamashita, K, Hirata, K, Ueno, G, Murakami, H, Hisano, T, Yamagiwa, R, Takeda, H, Gopalasingam, C, Yuki, K, Kousaka, R, Yanagasawa, S, Shoji, O, Kumasaka, T, Takano, Y, Ago, H, Yamamoto, M, Sugimoto, H, Tosha, T, Kubo, M, Shiro, Y. 登録日 2021-01-14 公開日 2021-05-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Short-lived intermediate in N 2 O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography. Proc.Natl.Acad.Sci.USA, 118, 2021
4DW2	The crystal structure of uPA in complex with the Fab fragment of mAb-112 分子名称: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator 著者 Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. 登録日 2012-02-24 公開日 2013-01-16 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
6GCH	STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS 分子名称: 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), GAMMA-CHYMOTRYPSIN A 著者 Brady, K, Wei, A, Ringe, D, Abeles, R.H. 登録日 1990-04-06 公開日 1990-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. Biochemistry, 29, 1990
6GHH	Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin 分子名称: Beta-lactoglobulin, N-TRIDECANOIC ACID 著者 Kontopidis, G, Rovoli, M. 登録日 2018-05-07 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Thermodynamic, crystallographic and computational studies of non-mammalian fatty acid binding to bovine beta-Lactoglobulin. Int. J. Biol. Macromol., 118, 2018
3MJU	Crystal structure determination of pigeon (columba livia) haemoglobin at 3.5 angstrom resolution 分子名称: Hemoglobin subunit alpha-A, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Sathya Moorthy, P, Balasubramanian, M, Thenmozhi, M, Ponnuswamy, M.N. 登録日 2010-04-13 公開日 2010-12-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure determination of pigeon (columba livia) haemoglobin at 3.5 angstrom resolution To be Published
6GF0	Lysozyme structure determined from SFX data using a Sheet-on-Sheet chipless chip 分子名称: Lysozyme C 著者 Doak, R.B, Gorel, A, Foucar, L, Gruenbein, M.L, Hilpert, M, Kloos, M, Nass Kovacs, G, Roome, C, Shoeman, R.L, Stricker, M, Tono, K, You, D, Ueda, K, Sherrel, D, Owen, R, Barends, T.R.M, Schlichting, I. 登録日 2018-04-27 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Crystallography on a chip - without the chip: sheet-on-sheet sandwich. Acta Crystallogr D Struct Biol, 74, 2018
3MFP	Atomic model of F-actin based on a 6.6 angstrom resolution cryoEM map 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle 著者 Fujii, T, Iwane, A.H, Yanagida, T, Namba, K. 登録日 2010-04-03 公開日 2010-09-29 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Direct visualization of secondary structures of F-actin by electron cryomicroscopy Nature, 467, 2010
3MMN	Crystal structure of the receiver domain of the histidine kinase CKI1 from Arabidopsis thaliana complexed with Mg2+ 分子名称: Histidine kinase homolog, MAGNESIUM ION 著者 Marek, J, Klumpler, T, Pekarova, B, Triskova, O, Horak, J, Zidek, L, Dopitova, R, Hejatko, J, Janda, L. 登録日 2010-04-20 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and binding specificity of the receiver domain of sensor histidine kinase CKI1 from Arabidopsis thaliana. Plant J., 67, 2011
3MI4	Bovine trypsin at 0.8 A resolution, non-restrained refinement 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Brzuszkiewicz, A, Dauter, M, Dauter, Z. 登録日 2010-04-09 公開日 2010-04-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (0.8 Å) 主引用文献 Bovine trypsin at 0.8 A and role of restraints at ultra-high resolution To be Published
7DEQ	Lysozyme-sugar complex in D2O 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... 著者 Tanaka, I, Chatake, T. 登録日 2020-11-04 公開日 2021-03-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Recent structural insights into the mechanism of lysozyme hydrolysis. Acta Crystallogr D Struct Biol, 77, 2021
6GOE	KRAS full length G12V GPPNHP 分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER 著者 Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H. 登録日 2018-06-01 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3MKG	Low pH as-isolated tomato chloroplast superoxide dismutase 分子名称: Superoxide dismutase [Cu-Zn], chloroplastic, ZINC ION 著者 Galaleldeen, A, Taylor, A.B, Hart, P.J. 登録日 2010-04-14 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biophysical properties of tomato chloroplast sod To be Published
7DER	Lysozyme alone in H2O 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION 著者 Tanaka, I, Chatake, T. 登録日 2020-11-04 公開日 2021-03-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Recent structural insights into the mechanism of lysozyme hydrolysis. Acta Crystallogr D Struct Biol, 77, 2021
3MMV	Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... 著者 Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. 登録日 2010-04-20 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010

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